RL37A_HUMAN
ID RL37A_HUMAN Reviewed; 92 AA.
AC P61513; P12751; Q6FGF5;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 170.
DE RecName: Full=60S ribosomal protein L37a;
DE AltName: Full=Large ribosomal subunit protein eL43 {ECO:0000303|PubMed:24524803};
GN Name=RPL37A;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Nasal polyp;
RX PubMed=1437567; DOI=10.1093/nar/20.20.5475;
RA Hoof T., Fislage R., Tuemmler B.;
RT "Primary sequence of the human ribosomal protein L37a.";
RL Nucleic Acids Res. 20:5475-5475(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8479924; DOI=10.1093/nar/21.7.1672;
RA Chu W., Presky D.H., Swerlick R.A., Burns D.K.;
RT "Human ribosomal protein S20 cDNA sequence.";
RL Nucleic Acids Res. 21:1672-1672(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8224875; DOI=10.1016/0378-1119(93)90209-l;
RA Saha D.P., Tirumalai P.S., Scala L.A., Howells R.D.;
RT "Human ribosomal protein L37a: cloning of the cDNA and analysis of
RT differential gene expression in tissues and cell lines.";
RL Gene 132:285-289(1993).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Cerebellum;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.;
RT "Cloning of human full open reading frames in Gateway(TM) system entry
RT vector (pDONR201).";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=B-cell, Brain, Skin, and Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [9]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [10]
RP NOMENCLATURE.
RX PubMed=24524803; DOI=10.1016/j.sbi.2014.01.002;
RA Ban N., Beckmann R., Cate J.H.D., Dinman J.D., Dragon F., Ellis S.R.,
RA Lafontaine D.L.J., Lindahl L., Liljas A., Lipton J.M., McAlear M.A.,
RA Moore P.B., Noller H.F., Ortega J., Panse V.G., Ramakrishnan V.,
RA Spahn C.M.T., Steitz T.A., Tchorzewski M., Tollervey D., Warren A.J.,
RA Williamson J.R., Wilson D., Yonath A., Yusupov M.;
RT "A new system for naming ribosomal proteins.";
RL Curr. Opin. Struct. Biol. 24:165-169(2014).
RN [11]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=25944712; DOI=10.1002/pmic.201400617;
RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D.,
RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT "N-terminome analysis of the human mitochondrial proteome.";
RL Proteomics 15:2519-2524(2015).
RN [12]
RP STRUCTURE BY ELECTRON MICROSCOPY (5.0 ANGSTROMS), FUNCTION, SUBUNIT, AND
RP SUBCELLULAR LOCATION.
RX PubMed=23636399; DOI=10.1038/nature12104;
RA Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M.,
RA Wilson D.N., Beckmann R.;
RT "Structures of the human and Drosophila 80S ribosome.";
RL Nature 497:80-85(2013).
RN [13] {ECO:0007744|PDB:6LQM, ECO:0007744|PDB:6LSR, ECO:0007744|PDB:6LSS, ECO:0007744|PDB:6LU8}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.09 ANGSTROMS), FUNCTION, AND SUBUNIT.
RX PubMed=32669547; DOI=10.1038/s41467-020-17237-x;
RA Liang X., Zuo M.Q., Zhang Y., Li N., Ma C., Dong M.Q., Gao N.;
RT "Structural snapshots of human pre-60S ribosomal particles before and after
RT nuclear export.";
RL Nat. Commun. 11:3542-3542(2020).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000269|PubMed:23636399,
CC ECO:0000269|PubMed:32669547}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:32669547}.
CC -!- INTERACTION:
CC P61513; P43360: MAGEA6; NbExp=6; IntAct=EBI-356793, EBI-1045155;
CC P61513; P16284: PECAM1; NbExp=3; IntAct=EBI-356793, EBI-716404;
CC P61513; P17612: PRKACA; NbExp=3; IntAct=EBI-356793, EBI-476586;
CC P61513; P50454: SERPINH1; NbExp=3; IntAct=EBI-356793, EBI-350723;
CC P61513; P37173: TGFBR2; NbExp=3; IntAct=EBI-356793, EBI-296151;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23636399}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL43 family.
CC {ECO:0000305}.
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DR EMBL; L06499; AAA60280.1; -; mRNA.
DR EMBL; X66699; CAA47244.1; -; mRNA.
DR EMBL; L22154; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK289472; BAF82161.1; -; mRNA.
DR EMBL; CR542152; CAG46949.1; -; mRNA.
DR EMBL; AC073321; AAY15078.1; -; Genomic_DNA.
DR EMBL; CH471063; EAW70569.1; -; Genomic_DNA.
DR EMBL; BC000555; AAH00555.2; -; mRNA.
DR EMBL; BC014262; AAH14262.1; -; mRNA.
DR EMBL; BC016748; AAH16748.1; -; mRNA.
DR EMBL; BC067789; AAH67789.1; -; mRNA.
DR EMBL; BC082239; AAH82239.1; -; mRNA.
DR CCDS; CCDS2404.1; -.
DR PIR; JN0875; JN0875.
DR RefSeq; NP_000989.1; NM_000998.4.
DR PDB; 4UG0; EM; -; Lp=1-92.
DR PDB; 4V6X; EM; 5.00 A; Cp=1-92.
DR PDB; 5AJ0; EM; 3.50 A; Ap=1-92.
DR PDB; 5LKS; EM; 3.60 A; Lp=1-92.
DR PDB; 5T2C; EM; 3.60 A; j=1-92.
DR PDB; 6IP5; EM; 3.90 A; 2j=1-92.
DR PDB; 6IP6; EM; 4.50 A; 2j=1-92.
DR PDB; 6IP8; EM; 3.90 A; 2j=1-92.
DR PDB; 6LQM; EM; 3.09 A; X=1-92.
DR PDB; 6LSR; EM; 3.13 A; X=1-92.
DR PDB; 6LSS; EM; 3.23 A; X=1-92.
DR PDB; 6LU8; EM; 3.13 A; X=1-92.
DR PDB; 6OLE; EM; 3.10 A; q=2-92.
DR PDB; 6OLF; EM; 3.90 A; q=2-92.
DR PDB; 6OLG; EM; 3.40 A; Ap=2-92.
DR PDB; 6OLI; EM; 3.50 A; q=2-92.
DR PDB; 6OLZ; EM; 3.90 A; Ap=2-92.
DR PDB; 6OM0; EM; 3.10 A; q=2-92.
DR PDB; 6OM7; EM; 3.70 A; q=2-92.
DR PDB; 6QZP; EM; 2.90 A; Lp=2-92.
DR PDB; 6W6L; EM; 3.84 A; q=1-92.
DR PDB; 6XA1; EM; 2.80 A; Lp=2-92.
DR PDB; 6Y0G; EM; 3.20 A; Lp=1-92.
DR PDB; 6Y2L; EM; 3.00 A; Lp=1-92.
DR PDB; 6Y57; EM; 3.50 A; Lp=1-92.
DR PDB; 6Y6X; EM; 2.80 A; Lp=2-92.
DR PDB; 6Z6L; EM; 3.00 A; Lp=1-92.
DR PDB; 6Z6M; EM; 3.10 A; Lp=1-92.
DR PDB; 6Z6N; EM; 2.90 A; Lp=1-92.
DR PDB; 6ZM7; EM; 2.70 A; Lp=1-92.
DR PDB; 6ZME; EM; 3.00 A; Lp=1-92.
DR PDB; 6ZMI; EM; 2.60 A; Lp=1-92.
DR PDB; 6ZMO; EM; 3.10 A; Lp=1-92.
DR PDB; 7BHP; EM; 3.30 A; Lp=1-92.
DR PDBsum; 4UG0; -.
DR PDBsum; 4V6X; -.
DR PDBsum; 5AJ0; -.
DR PDBsum; 5LKS; -.
DR PDBsum; 5T2C; -.
DR PDBsum; 6IP5; -.
DR PDBsum; 6IP6; -.
DR PDBsum; 6IP8; -.
DR PDBsum; 6LQM; -.
DR PDBsum; 6LSR; -.
DR PDBsum; 6LSS; -.
DR PDBsum; 6LU8; -.
DR PDBsum; 6OLE; -.
DR PDBsum; 6OLF; -.
DR PDBsum; 6OLG; -.
DR PDBsum; 6OLI; -.
DR PDBsum; 6OLZ; -.
DR PDBsum; 6OM0; -.
DR PDBsum; 6OM7; -.
DR PDBsum; 6QZP; -.
DR PDBsum; 6W6L; -.
DR PDBsum; 6XA1; -.
DR PDBsum; 6Y0G; -.
DR PDBsum; 6Y2L; -.
DR PDBsum; 6Y57; -.
DR PDBsum; 6Y6X; -.
DR PDBsum; 6Z6L; -.
DR PDBsum; 6Z6M; -.
DR PDBsum; 6Z6N; -.
DR PDBsum; 6ZM7; -.
DR PDBsum; 6ZME; -.
DR PDBsum; 6ZMI; -.
DR PDBsum; 6ZMO; -.
DR PDBsum; 7BHP; -.
DR AlphaFoldDB; P61513; -.
DR SMR; P61513; -.
DR BioGRID; 112087; 347.
DR ComplexPortal; CPX-5183; 60S cytosolic large ribosomal subunit.
DR CORUM; P61513; -.
DR IntAct; P61513; 163.
DR MINT; P61513; -.
DR STRING; 9606.ENSP00000418082; -.
DR GlyGen; P61513; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; P61513; -.
DR MetOSite; P61513; -.
DR PhosphoSitePlus; P61513; -.
DR SwissPalm; P61513; -.
DR BioMuta; RPL37A; -.
DR DMDM; 47606455; -.
DR EPD; P61513; -.
DR jPOST; P61513; -.
DR MassIVE; P61513; -.
DR MaxQB; P61513; -.
DR PaxDb; P61513; -.
DR PeptideAtlas; P61513; -.
DR PRIDE; P61513; -.
DR ProteomicsDB; 57302; -.
DR TopDownProteomics; P61513; -.
DR Antibodypedia; 35073; 96 antibodies from 24 providers.
DR DNASU; 6168; -.
DR Ensembl; ENST00000491306.6; ENSP00000418082.1; ENSG00000197756.10.
DR GeneID; 6168; -.
DR KEGG; hsa:6168; -.
DR MANE-Select; ENST00000491306.6; ENSP00000418082.1; NM_000998.5; NP_000989.1.
DR UCSC; uc002vgf.4; human.
DR CTD; 6168; -.
DR DisGeNET; 6168; -.
DR GeneCards; RPL37A; -.
DR HGNC; HGNC:10348; RPL37A.
DR HPA; ENSG00000197756; Low tissue specificity.
DR MIM; 613314; gene.
DR neXtProt; NX_P61513; -.
DR OpenTargets; ENSG00000197756; -.
DR PharmGKB; PA34737; -.
DR VEuPathDB; HostDB:ENSG00000197756; -.
DR eggNOG; KOG0402; Eukaryota.
DR GeneTree; ENSGT00390000016988; -.
DR HOGENOM; CLU_141199_1_0_1; -.
DR InParanoid; P61513; -.
DR OMA; ISTGIWQ; -.
DR OrthoDB; 1621758at2759; -.
DR PhylomeDB; P61513; -.
DR TreeFam; TF313068; -.
DR PathwayCommons; P61513; -.
DR Reactome; R-HSA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-HSA-156902; Peptide chain elongation.
DR Reactome; R-HSA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-HSA-192823; Viral mRNA Translation.
DR Reactome; R-HSA-2408557; Selenocysteine synthesis.
DR Reactome; R-HSA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-HSA-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-HSA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-HSA-72764; Eukaryotic Translation Termination.
DR Reactome; R-HSA-9010553; Regulation of expression of SLITs and ROBOs.
DR Reactome; R-HSA-9633012; Response of EIF2AK4 (GCN2) to amino acid deficiency.
DR Reactome; R-HSA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-HSA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR SignaLink; P61513; -.
DR SIGNOR; P61513; -.
DR BioGRID-ORCS; 6168; 798 hits in 1054 CRISPR screens.
DR ChiTaRS; RPL37A; human.
DR GeneWiki; RPL37A; -.
DR GenomeRNAi; 6168; -.
DR Pharos; P61513; Tbio.
DR PRO; PR:P61513; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; P61513; protein.
DR Bgee; ENSG00000197756; Expressed in upper leg skin and 207 other tissues.
DR ExpressionAtlas; P61513; baseline and differential.
DR Genevisible; P61513; HS.
DR GO; GO:0005737; C:cytoplasm; IC:ComplexPortal.
DR GO; GO:0005829; C:cytosol; TAS:Reactome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IPI:ComplexPortal.
DR GO; GO:0022626; C:cytosolic ribosome; IDA:FlyBase.
DR GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB.
DR GO; GO:0005925; C:focal adhesion; HDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; HDA:UniProtKB.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; HDA:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
DR GO; GO:0002181; P:cytoplasmic translation; IC:FlyBase.
DR GO; GO:0006412; P:translation; NAS:UniProtKB.
DR Gene3D; 2.20.25.30; -; 1.
DR HAMAP; MF_00327; Ribosomal_L37Ae; 1.
DR InterPro; IPR002674; Ribosomal_L37ae.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01780; Ribosomal_L37ae; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR TIGRFAMs; TIGR00280; eL43_euk_arch; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Metal-binding; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Zinc; Zinc-finger.
FT CHAIN 1..92
FT /note="60S ribosomal protein L37a"
FT /id="PRO_0000139817"
FT ZN_FING 39..60
FT /note="C4-type"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 42
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
SQ SEQUENCE 92 AA; 10275 MW; 7122AF87B0E24CF6 CRC64;
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC
MKTVAGGAWT YNTTSAVTVK SAIRRLKELK DQ
