RL37A_PONAB
ID RL37A_PONAB Reviewed; 92 AA.
AC Q5RBF9;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=60S ribosomal protein L37a;
GN Name=RPL37A;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Heart;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P61513}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P61513}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P61513}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL43 family.
CC {ECO:0000305}.
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DR EMBL; CR858690; CAH90901.1; -; mRNA.
DR RefSeq; NP_001125513.1; NM_001132041.2.
DR RefSeq; XP_002819379.1; XM_002819333.3.
DR AlphaFoldDB; Q5RBF9; -.
DR SMR; Q5RBF9; -.
DR STRING; 9601.ENSPPYP00000021078; -.
DR Ensembl; ENSPPYT00000021921; ENSPPYP00000021078; ENSPPYG00000018792.
DR GeneID; 100172423; -.
DR GeneID; 100458923; -.
DR KEGG; pon:100172423; -.
DR KEGG; pon:100458923; -.
DR CTD; 6168; -.
DR eggNOG; KOG0402; Eukaryota.
DR GeneTree; ENSGT00390000016988; -.
DR HOGENOM; CLU_141199_1_0_1; -.
DR InParanoid; Q5RBF9; -.
DR OMA; ISTGIWQ; -.
DR OrthoDB; 1621758at2759; -.
DR TreeFam; TF313068; -.
DR Proteomes; UP000001595; Chromosome 8.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.20.25.30; -; 1.
DR HAMAP; MF_00327; Ribosomal_L37Ae; 1.
DR InterPro; IPR002674; Ribosomal_L37ae.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01780; Ribosomal_L37ae; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR TIGRFAMs; TIGR00280; eL43_euk_arch; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Zinc; Zinc-finger.
FT CHAIN 1..92
FT /note="60S ribosomal protein L37a"
FT /id="PRO_0000265735"
FT ZN_FING 39..60
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 42
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 57
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P49166"
SQ SEQUENCE 92 AA; 10275 MW; 7122AF87B0E24CF6 CRC64;
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC
MKTVAGGAWT YNTTSAVTVK SAIRRLKELK DQ