RL37A_YEAST
ID RL37A_YEAST Reviewed; 88 AA.
AC P49166; D6VYI8;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 175.
DE RecName: Full=60S ribosomal protein L37-A {ECO:0000303|PubMed:9559554};
DE AltName: Full=L43;
DE AltName: Full=Large ribosomal subunit protein eL37-A {ECO:0000303|PubMed:24524803};
DE AltName: Full=YL35;
DE AltName: Full=YP55;
GN Name=RPL37A {ECO:0000303|PubMed:9559554}; Synonyms=RPL35A;
GN OrderedLocusNames=YLR185W; ORFNames=L9470.6;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169871;
RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA Zollner A., Hani J., Hoheisel J.D.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL Nature 387:87-90(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP PROTEIN SEQUENCE OF 2-88.
RA Itoh T., Higo K., Otaka E., Osawa S.;
RT "Studies on the primary structures of yeast ribosomal proteins.";
RL (In) Osawa S., Ozeki H., Uchida H., Yura T. (eds.);
RL Genetics and evolution of RNA polymerase, tRNA and ribosomes, pp.609-624,
RL University of Tokyo Press, Tokyo (1980).
RN [4]
RP NOMENCLATURE, AND SUBUNIT.
RX PubMed=9559554;
RX DOI=10.1002/(sici)1097-0061(19980330)14:5<471::aid-yea241>3.0.co;2-u;
RA Planta R.J., Mager W.H.;
RT "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.";
RL Yeast 14:471-477(1998).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [7]
RP NOMENCLATURE.
RX PubMed=24524803; DOI=10.1016/j.sbi.2014.01.002;
RA Ban N., Beckmann R., Cate J.H.D., Dinman J.D., Dragon F., Ellis S.R.,
RA Lafontaine D.L.J., Lindahl L., Liljas A., Lipton J.M., McAlear M.A.,
RA Moore P.B., Noller H.F., Ortega J., Panse V.G., Ramakrishnan V.,
RA Spahn C.M.T., Steitz T.A., Tchorzewski M., Tollervey D., Warren A.J.,
RA Williamson J.R., Wilson D., Yonath A., Yusupov M.;
RT "A new system for naming ribosomal proteins.";
RL Curr. Opin. Struct. Biol. 24:165-169(2014).
RN [8]
RP 3D-STRUCTURE MODELING OF 2-53, AND ELECTRON MICROSCOPY.
RX PubMed=11701127; DOI=10.1016/s0092-8674(01)00539-6;
RA Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G.,
RA Frank J.;
RT "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-
RT ribosome and subunit-subunit interactions.";
RL Cell 107:373-386(2001).
RN [9]
RP 3D-STRUCTURE MODELING, AND ELECTRON MICROSCOPY.
RX PubMed=14976550; DOI=10.1038/sj.emboj.7600102;
RA Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R.,
RA Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J.;
RT "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome
RT facilitate tRNA translocation.";
RL EMBO J. 23:1008-1019(2004).
RN [10]
RP X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 80S RIBOSOME.
RX PubMed=21109664; DOI=10.1126/science.1194294;
RA Ben-Shem A., Jenner L., Yusupova G., Yusupov M.;
RT "Crystal structure of the eukaryotic ribosome.";
RL Science 330:1203-1209(2010).
RN [11]
RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 80S RIBOSOME, SUBUNIT, SUBCELLULAR
RP LOCATION, AND ZINC-BINDING.
RX PubMed=22096102; DOI=10.1126/science.1212642;
RA Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G.,
RA Yusupov M.;
RT "The structure of the eukaryotic ribosome at 3.0 A resolution.";
RL Science 334:1524-1529(2011).
CC -!- FUNCTION: Component of the ribosome, a large ribonucleoprotein complex
CC responsible for the synthesis of proteins in the cell. The small
CC ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the
CC encoded message by selecting cognate aminoacyl-transfer RNA (tRNA)
CC molecules. The large subunit (LSU) contains the ribosomal catalytic
CC site termed the peptidyl transferase center (PTC), which catalyzes the
CC formation of peptide bonds, thereby polymerizing the amino acids
CC delivered by tRNAs into a polypeptide chain. The nascent polypeptides
CC leave the ribosome through a tunnel in the LSU and interact with
CC protein factors that function in enzymatic processing, targeting, and
CC the membrane insertion of nascent chains at the exit of the ribosomal
CC tunnel. {ECO:0000305|PubMed:22096102}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000269|PubMed:22096102};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000269|PubMed:22096102};
CC -!- SUBUNIT: Component of the large ribosomal subunit (LSU). Mature yeast
CC ribosomes consist of a small (40S) and a large (60S) subunit. The 40S
CC small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33
CC different proteins (encoded by 57 genes). The large 60S subunit
CC contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different
CC proteins (encoded by 81 genes) (PubMed:9559554, PubMed:22096102).
CC {ECO:0000269|PubMed:22096102, ECO:0000305|PubMed:9559554}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095,
CC ECO:0000269|PubMed:22096102}.
CC -!- MISCELLANEOUS: Present with 21800 molecules/cell in log phase SD
CC medium. {ECO:0000269|PubMed:14562106}.
CC -!- MISCELLANEOUS: There are 2 genes for eL37 in yeast. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL37 family.
CC {ECO:0000305}.
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DR EMBL; U17246; AAB67458.1; -; Genomic_DNA.
DR EMBL; BK006945; DAA09504.1; -; Genomic_DNA.
DR PIR; S51430; S51430.
DR RefSeq; NP_013286.1; NM_001182072.1.
DR PDB; 3J6X; EM; 6.10 A; 77=1-88.
DR PDB; 3J6Y; EM; 6.10 A; 77=1-88.
DR PDB; 3J77; EM; 6.20 A; 87=1-88.
DR PDB; 3J78; EM; 6.30 A; 87=1-88.
DR PDB; 3JCT; EM; 3.08 A; j=1-88.
DR PDB; 4U3M; X-ray; 3.00 A; O7/o7=2-88.
DR PDB; 4U3N; X-ray; 3.20 A; O7/o7=2-88.
DR PDB; 4U3U; X-ray; 2.90 A; O7/o7=2-88.
DR PDB; 4U4N; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 4U4O; X-ray; 3.60 A; O7/o7=2-88.
DR PDB; 4U4Q; X-ray; 3.00 A; O7/o7=2-88.
DR PDB; 4U4R; X-ray; 2.80 A; O7/o7=2-88.
DR PDB; 4U4U; X-ray; 3.00 A; O7/o7=2-88.
DR PDB; 4U4Y; X-ray; 3.20 A; O7/o7=2-88.
DR PDB; 4U4Z; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 4U50; X-ray; 3.20 A; O7/o7=2-88.
DR PDB; 4U51; X-ray; 3.20 A; O7/o7=2-88.
DR PDB; 4U52; X-ray; 3.00 A; O7/o7=2-88.
DR PDB; 4U53; X-ray; 3.30 A; O7/o7=2-88.
DR PDB; 4U55; X-ray; 3.20 A; O7/o7=2-88.
DR PDB; 4U56; X-ray; 3.45 A; O7/o7=2-88.
DR PDB; 4U6F; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 4V4B; EM; 11.70 A; BY=2-88.
DR PDB; 4V6I; EM; 8.80 A; Bl=1-88.
DR PDB; 4V7F; EM; 8.70 A; h=1-88.
DR PDB; 4V7R; X-ray; 4.00 A; Bd/Dd=1-88.
DR PDB; 4V88; X-ray; 3.00 A; Bj/Dj=1-88.
DR PDB; 4V8T; EM; 8.10 A; j=1-88.
DR PDB; 4V8Y; EM; 4.30 A; Bj=2-88.
DR PDB; 4V8Z; EM; 6.60 A; Bj=2-88.
DR PDB; 4V91; EM; 3.70 A; j=1-88.
DR PDB; 5APN; EM; 3.91 A; j=1-88.
DR PDB; 5APO; EM; 3.41 A; j=1-88.
DR PDB; 5DAT; X-ray; 3.15 A; O7/o7=2-88.
DR PDB; 5DC3; X-ray; 3.25 A; O7/o7=2-88.
DR PDB; 5DGE; X-ray; 3.45 A; O7/o7=2-88.
DR PDB; 5DGF; X-ray; 3.30 A; O7/o7=2-88.
DR PDB; 5DGV; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 5FCI; X-ray; 3.40 A; O7/o7=2-88.
DR PDB; 5FCJ; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 5FL8; EM; 9.50 A; j=1-88.
DR PDB; 5GAK; EM; 3.88 A; l=1-88.
DR PDB; 5H4P; EM; 3.07 A; j=1-88.
DR PDB; 5I4L; X-ray; 3.10 A; O7/o7=2-88.
DR PDB; 5JCS; EM; 9.50 A; j=1-88.
DR PDB; 5JUO; EM; 4.00 A; OA=1-88.
DR PDB; 5JUP; EM; 3.50 A; OA=1-88.
DR PDB; 5JUS; EM; 4.20 A; OA=1-88.
DR PDB; 5JUT; EM; 4.00 A; OA=1-88.
DR PDB; 5JUU; EM; 4.00 A; OA=1-88.
DR PDB; 5LYB; X-ray; 3.25 A; O7/o7=2-88.
DR PDB; 5M1J; EM; 3.30 A; j5=2-88.
DR PDB; 5MC6; EM; 3.80 A; AF=1-88.
DR PDB; 5MEI; X-ray; 3.50 A; AK/DL=2-88.
DR PDB; 5NDG; X-ray; 3.70 A; O7/o7=2-85.
DR PDB; 5NDV; X-ray; 3.30 A; O7/o7=2-88.
DR PDB; 5NDW; X-ray; 3.70 A; O7/o7=2-88.
DR PDB; 5OBM; X-ray; 3.40 A; O7/o7=2-88.
DR PDB; 5ON6; X-ray; 3.10 A; AK/DL=2-88.
DR PDB; 5T62; EM; 3.30 A; w=1-88.
DR PDB; 5T6R; EM; 4.50 A; w=1-88.
DR PDB; 5TBW; X-ray; 3.00 A; AK/DL=2-88.
DR PDB; 5TGA; X-ray; 3.30 A; O7/o7=2-88.
DR PDB; 5TGM; X-ray; 3.50 A; O7/o7=2-88.
DR PDB; 5Z3G; EM; 3.65 A; n=1-88.
DR PDB; 6C0F; EM; 3.70 A; j=1-88.
DR PDB; 6CB1; EM; 4.60 A; j=1-88.
DR PDB; 6ELZ; EM; 3.30 A; j=1-88.
DR PDB; 6EM1; EM; 3.60 A; j=1-88.
DR PDB; 6EM3; EM; 3.20 A; j=1-88.
DR PDB; 6EM4; EM; 4.10 A; j=1-88.
DR PDB; 6EM5; EM; 4.30 A; j=1-88.
DR PDB; 6FT6; EM; 3.90 A; j=1-88.
DR PDB; 6GQ1; EM; 4.40 A; j=2-88.
DR PDB; 6GQB; EM; 3.90 A; j=2-88.
DR PDB; 6GQV; EM; 4.00 A; j=2-88.
DR PDB; 6HD7; EM; 3.40 A; l=1-88.
DR PDB; 6HHQ; X-ray; 3.10 A; AK/DL=1-88.
DR PDB; 6I7O; EM; 5.30 A; AF/XF=2-83.
DR PDB; 6M62; EM; 3.20 A; j=1-88.
DR PDB; 6N8J; EM; 3.50 A; j=1-88.
DR PDB; 6N8K; EM; 3.60 A; j=1-88.
DR PDB; 6N8L; EM; 3.60 A; j=1-88.
DR PDB; 6N8M; EM; 3.50 A; w=1-88.
DR PDB; 6N8N; EM; 3.80 A; w=1-88.
DR PDB; 6N8O; EM; 3.50 A; w=1-88.
DR PDB; 6OIG; EM; 3.80 A; j=2-88.
DR PDB; 6Q8Y; EM; 3.10 A; AF=2-88.
DR PDB; 6QIK; EM; 3.10 A; i=1-88.
DR PDB; 6QT0; EM; 3.40 A; i=1-88.
DR PDB; 6QTZ; EM; 3.50 A; i=1-88.
DR PDB; 6R84; EM; 3.60 A; l=2-88.
DR PDB; 6R86; EM; 3.40 A; l=2-88.
DR PDB; 6R87; EM; 3.40 A; l=2-88.
DR PDB; 6RI5; EM; 3.30 A; i=1-88.
DR PDB; 6RZZ; EM; 3.20 A; i=1-88.
DR PDB; 6S05; EM; 3.90 A; i=1-88.
DR PDB; 6S47; EM; 3.28 A; Al=2-88.
DR PDB; 6SNT; EM; 2.80 A; ag=1-88.
DR PDB; 6SV4; EM; 3.30 A; AF/XF/zF=1-88.
DR PDB; 6T4Q; EM; 2.60 A; Lj=2-86.
DR PDB; 6T7I; EM; 3.20 A; Lj=1-88.
DR PDB; 6T7T; EM; 3.10 A; Lj=1-88.
DR PDB; 6T83; EM; 4.00 A; U/jb=1-88.
DR PDB; 6TB3; EM; 2.80 A; AF=2-82.
DR PDB; 6TNU; EM; 3.10 A; AF=2-82.
DR PDB; 6WOO; EM; 2.90 A; j=2-83.
DR PDB; 6XIQ; EM; 4.20 A; j=1-88.
DR PDB; 6XIR; EM; 3.20 A; j=1-88.
DR PDB; 6YLG; EM; 3.00 A; j=1-88.
DR PDB; 6YLH; EM; 3.10 A; j=1-88.
DR PDB; 6YLX; EM; 3.90 A; j=1-88.
DR PDB; 6YLY; EM; 3.80 A; j=1-88.
DR PDB; 6Z6J; EM; 3.40 A; Lj=1-88.
DR PDB; 6Z6K; EM; 3.40 A; Lj=1-88.
DR PDB; 7AZY; EM; 2.88 A; g=1-88.
DR PDB; 7B7D; EM; 3.30 A; Lf=2-82.
DR PDB; 7BT6; EM; 3.12 A; j=1-88.
DR PDB; 7BTB; EM; 3.22 A; j=1-88.
DR PDB; 7NRC; EM; 3.90 A; Ll=2-82.
DR PDB; 7NRD; EM; 4.36 A; Ll=2-82.
DR PDB; 7OF1; EM; 3.10 A; j=1-88.
DR PDB; 7OH3; EM; 3.40 A; j=1-88.
DR PDB; 7OHP; EM; 3.90 A; j=1-88.
DR PDB; 7OHQ; EM; 3.10 A; j=1-88.
DR PDB; 7OHR; EM; 4.72 A; j=1-88.
DR PDB; 7OHS; EM; 4.38 A; j=1-88.
DR PDB; 7OHU; EM; 3.70 A; j=1-88.
DR PDB; 7OHV; EM; 3.90 A; j=1-88.
DR PDB; 7OHW; EM; 3.50 A; j=1-88.
DR PDB; 7OHX; EM; 3.30 A; j=1-88.
DR PDB; 7OHY; EM; 3.90 A; j=1-88.
DR PDBsum; 3J6X; -.
DR PDBsum; 3J6Y; -.
DR PDBsum; 3J77; -.
DR PDBsum; 3J78; -.
DR PDBsum; 3JCT; -.
DR PDBsum; 4U3M; -.
DR PDBsum; 4U3N; -.
DR PDBsum; 4U3U; -.
DR PDBsum; 4U4N; -.
DR PDBsum; 4U4O; -.
DR PDBsum; 4U4Q; -.
DR PDBsum; 4U4R; -.
DR PDBsum; 4U4U; -.
DR PDBsum; 4U4Y; -.
DR PDBsum; 4U4Z; -.
DR PDBsum; 4U50; -.
DR PDBsum; 4U51; -.
DR PDBsum; 4U52; -.
DR PDBsum; 4U53; -.
DR PDBsum; 4U55; -.
DR PDBsum; 4U56; -.
DR PDBsum; 4U6F; -.
DR PDBsum; 4V4B; -.
DR PDBsum; 4V6I; -.
DR PDBsum; 4V7F; -.
DR PDBsum; 4V7R; -.
DR PDBsum; 4V88; -.
DR PDBsum; 4V8T; -.
DR PDBsum; 4V8Y; -.
DR PDBsum; 4V8Z; -.
DR PDBsum; 4V91; -.
DR PDBsum; 5APN; -.
DR PDBsum; 5APO; -.
DR PDBsum; 5DAT; -.
DR PDBsum; 5DC3; -.
DR PDBsum; 5DGE; -.
DR PDBsum; 5DGF; -.
DR PDBsum; 5DGV; -.
DR PDBsum; 5FCI; -.
DR PDBsum; 5FCJ; -.
DR PDBsum; 5FL8; -.
DR PDBsum; 5GAK; -.
DR PDBsum; 5H4P; -.
DR PDBsum; 5I4L; -.
DR PDBsum; 5JCS; -.
DR PDBsum; 5JUO; -.
DR PDBsum; 5JUP; -.
DR PDBsum; 5JUS; -.
DR PDBsum; 5JUT; -.
DR PDBsum; 5JUU; -.
DR PDBsum; 5LYB; -.
DR PDBsum; 5M1J; -.
DR PDBsum; 5MC6; -.
DR PDBsum; 5MEI; -.
DR PDBsum; 5NDG; -.
DR PDBsum; 5NDV; -.
DR PDBsum; 5NDW; -.
DR PDBsum; 5OBM; -.
DR PDBsum; 5ON6; -.
DR PDBsum; 5T62; -.
DR PDBsum; 5T6R; -.
DR PDBsum; 5TBW; -.
DR PDBsum; 5TGA; -.
DR PDBsum; 5TGM; -.
DR PDBsum; 5Z3G; -.
DR PDBsum; 6C0F; -.
DR PDBsum; 6CB1; -.
DR PDBsum; 6ELZ; -.
DR PDBsum; 6EM1; -.
DR PDBsum; 6EM3; -.
DR PDBsum; 6EM4; -.
DR PDBsum; 6EM5; -.
DR PDBsum; 6FT6; -.
DR PDBsum; 6GQ1; -.
DR PDBsum; 6GQB; -.
DR PDBsum; 6GQV; -.
DR PDBsum; 6HD7; -.
DR PDBsum; 6HHQ; -.
DR PDBsum; 6I7O; -.
DR PDBsum; 6M62; -.
DR PDBsum; 6N8J; -.
DR PDBsum; 6N8K; -.
DR PDBsum; 6N8L; -.
DR PDBsum; 6N8M; -.
DR PDBsum; 6N8N; -.
DR PDBsum; 6N8O; -.
DR PDBsum; 6OIG; -.
DR PDBsum; 6Q8Y; -.
DR PDBsum; 6QIK; -.
DR PDBsum; 6QT0; -.
DR PDBsum; 6QTZ; -.
DR PDBsum; 6R84; -.
DR PDBsum; 6R86; -.
DR PDBsum; 6R87; -.
DR PDBsum; 6RI5; -.
DR PDBsum; 6RZZ; -.
DR PDBsum; 6S05; -.
DR PDBsum; 6S47; -.
DR PDBsum; 6SNT; -.
DR PDBsum; 6SV4; -.
DR PDBsum; 6T4Q; -.
DR PDBsum; 6T7I; -.
DR PDBsum; 6T7T; -.
DR PDBsum; 6T83; -.
DR PDBsum; 6TB3; -.
DR PDBsum; 6TNU; -.
DR PDBsum; 6WOO; -.
DR PDBsum; 6XIQ; -.
DR PDBsum; 6XIR; -.
DR PDBsum; 6YLG; -.
DR PDBsum; 6YLH; -.
DR PDBsum; 6YLX; -.
DR PDBsum; 6YLY; -.
DR PDBsum; 6Z6J; -.
DR PDBsum; 6Z6K; -.
DR PDBsum; 7AZY; -.
DR PDBsum; 7B7D; -.
DR PDBsum; 7BT6; -.
DR PDBsum; 7BTB; -.
DR PDBsum; 7NRC; -.
DR PDBsum; 7NRD; -.
DR PDBsum; 7OF1; -.
DR PDBsum; 7OH3; -.
DR PDBsum; 7OHP; -.
DR PDBsum; 7OHQ; -.
DR PDBsum; 7OHR; -.
DR PDBsum; 7OHS; -.
DR PDBsum; 7OHU; -.
DR PDBsum; 7OHV; -.
DR PDBsum; 7OHW; -.
DR PDBsum; 7OHX; -.
DR PDBsum; 7OHY; -.
DR AlphaFoldDB; P49166; -.
DR SMR; P49166; -.
DR BioGRID; 31455; 254.
DR DIP; DIP-2135N; -.
DR IntAct; P49166; 5.
DR MINT; P49166; -.
DR STRING; 4932.YLR185W; -.
DR CarbonylDB; P49166; -.
DR iPTMnet; P49166; -.
DR MaxQB; P49166; -.
DR PaxDb; P49166; -.
DR PRIDE; P49166; -.
DR EnsemblFungi; YLR185W_mRNA; YLR185W; YLR185W.
DR GeneID; 850882; -.
DR KEGG; sce:YLR185W; -.
DR SGD; S000004175; RPL37A.
DR VEuPathDB; FungiDB:YLR185W; -.
DR eggNOG; KOG3475; Eukaryota.
DR GeneTree; ENSGT00940000168926; -.
DR HOGENOM; CLU_150908_2_1_1; -.
DR InParanoid; P49166; -.
DR OMA; RMAYLKH; -.
DR BioCyc; YEAST:G3O-32308-MON; -.
DR Reactome; R-SCE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-SCE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-SCE-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-SCE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-SCE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-SCE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR EvolutionaryTrace; P49166; -.
DR PRO; PR:P49166; -.
DR Proteomes; UP000002311; Chromosome XII.
DR RNAct; P49166; protein.
DR GO; GO:0005829; C:cytosol; TAS:Reactome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IDA:SGD.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IDA:SGD.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IC:SGD.
DR GO; GO:0000448; P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD.
DR GO; GO:0002181; P:cytoplasmic translation; IC:SGD.
DR Gene3D; 2.20.25.30; -; 1.
DR HAMAP; MF_00547; Ribosomal_L37e; 1.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR001569; Ribosomal_L37e.
DR InterPro; IPR018267; Ribosomal_L37e_CS.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01907; Ribosomal_L37e; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR PROSITE; PS01077; RIBOSOMAL_L37E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Direct protein sequencing; Metal-binding;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding; Zinc; Zinc-finger.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|Ref.3"
FT CHAIN 2..88
FT /note="60S ribosomal protein L37-A"
FT /id="PRO_0000139722"
FT ZN_FING 19..37
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT BINDING 19
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000269|PubMed:22096102"
FT BINDING 22
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000269|PubMed:22096102"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000269|PubMed:22096102"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000269|PubMed:22096102"
FT CONFLICT 73
FT /note="R -> RR (in Ref. 3; AA sequence)"
FT /evidence="ECO:0000305"
FT TURN 20..22
FT /evidence="ECO:0007829|PDB:6EM3"
FT TURN 29..32
FT /evidence="ECO:0007829|PDB:6EM3"
FT STRAND 33..37
FT /evidence="ECO:0007829|PDB:6EM3"
FT STRAND 41..43
FT /evidence="ECO:0007829|PDB:6EM3"
FT HELIX 51..56
FT /evidence="ECO:0007829|PDB:6EM3"
FT HELIX 67..69
FT /evidence="ECO:0007829|PDB:6EM3"
FT HELIX 70..76
FT /evidence="ECO:0007829|PDB:6EM3"
SQ SEQUENCE 88 AA; 9850 MW; 274D249361EBE5E5 CRC64;
MGKGTPSFGK RHNKSHTLCN RCGRRSFHVQ KKTCSSCGYP AAKTRSYNWG AKAKRRHTTG
TGRMRYLKHV SRRFKNGFQT GSASKASA
