RL37_ENCCU
ID RL37_ENCCU Reviewed; 90 AA.
AC Q8SRH5;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=60S ribosomal protein L37;
GN Name=RPL37; OrderedLocusNames=ECU07_1460;
OS Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=284813;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB-M1;
RX PubMed=11719806; DOI=10.1038/35106579;
RA Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA Vivares C.P.;
RT "Genome sequence and gene compaction of the eukaryote parasite
RT Encephalitozoon cuniculi.";
RL Nature 414:450-453(2001).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000250}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL37 family.
CC {ECO:0000305}.
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DR EMBL; AL590447; CAD25678.1; -; Genomic_DNA.
DR RefSeq; NP_586074.1; NM_001041696.1.
DR PDB; 7QEP; EM; 2.70 A; O7=1-90.
DR PDBsum; 7QEP; -.
DR AlphaFoldDB; Q8SRH5; -.
DR SMR; Q8SRH5; -.
DR STRING; 284813.Q8SRH5; -.
DR GeneID; 859504; -.
DR KEGG; ecu:ECU07_1460; -.
DR VEuPathDB; MicrosporidiaDB:ECU07_1460; -.
DR HOGENOM; CLU_150908_2_1_1; -.
DR InParanoid; Q8SRH5; -.
DR OMA; RMAYLKH; -.
DR OrthoDB; 1560654at2759; -.
DR Proteomes; UP000000819; Chromosome VII.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.20.25.30; -; 1.
DR InterPro; IPR011331; Ribosomal_L37ae/L37e.
DR InterPro; IPR001569; Ribosomal_L37e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR Pfam; PF01907; Ribosomal_L37e; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Metal-binding; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; rRNA-binding; Zinc; Zinc-finger.
FT CHAIN 1..90
FT /note="60S ribosomal protein L37"
FT /id="PRO_0000370507"
FT ZN_FING 19..37
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT REGION 21..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 19
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 22
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
SQ SEQUENCE 90 AA; 10388 MW; 40FC497C6DD35BCC CRC64;
MSKGTASFGK KNKRNTEMCR RCGRQSYHKQ KNSCSSCGYP NPKMRNPGSI KARRRRTIGT
GRMRYMKREL RAAKNGHKGD PILRTLWAKN
