RL3_ENTFA
ID RL3_ENTFA Reviewed; 209 AA.
AC Q839G4;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=EF_0206;
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583;
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; AE016830; AAO80075.1; -; Genomic_DNA.
DR RefSeq; NP_814004.1; NC_004668.1.
DR RefSeq; WP_002356199.1; NZ_KE136524.1.
DR PDB; 6WU9; EM; 2.90 A; D=2-208.
DR PDB; 7P7R; EM; 2.90 A; H=1-209.
DR PDBsum; 6WU9; -.
DR PDBsum; 7P7R; -.
DR AlphaFoldDB; Q839G4; -.
DR SMR; Q839G4; -.
DR STRING; 226185.EF_0206; -.
DR PRIDE; Q839G4; -.
DR EnsemblBacteria; AAO80075; AAO80075; EF_0206.
DR GeneID; 60892701; -.
DR KEGG; efa:EF0206; -.
DR PATRIC; fig|226185.45.peg.60; -.
DR eggNOG; COG0087; Bacteria.
DR HOGENOM; CLU_044142_4_1_9; -.
DR OMA; KRMAGRY; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01325_B; Ribosomal_L3_B; 1.
DR InterPro; IPR000597; Ribosomal_L3.
DR InterPro; IPR019927; Ribosomal_L3_bac/org-type.
DR InterPro; IPR019926; Ribosomal_L3_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11229; PTHR11229; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR03625; L3_bact; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..209
FT /note="50S ribosomal protein L3"
FT /id="PRO_0000077101"
FT REGION 118..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 4..16
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 22..29
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 33..39
FT /evidence="ECO:0007829|PDB:6WU9"
FT TURN 41..44
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 48..55
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 58..61
FT /evidence="ECO:0007829|PDB:6WU9"
FT HELIX 63..70
FT /evidence="ECO:0007829|PDB:6WU9"
FT TURN 71..73
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 77..85
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 88..90
FT /evidence="ECO:0007829|PDB:6WU9"
FT HELIX 99..101
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 104..113
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 116..120
FT /evidence="ECO:0007829|PDB:6WU9"
FT HELIX 122..126
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 162..165
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 168..180
FT /evidence="ECO:0007829|PDB:6WU9"
FT TURN 181..184
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 185..190
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 199..204
FT /evidence="ECO:0007829|PDB:6WU9"
SQ SEQUENCE 209 AA; 22717 MW; E9EB13F772D85AEB CRC64;
MTKGILGKKV GMTQIFTESG ELIPVTVVEA TPNVVLQVKT VETDGYEAIQ VGYQDKREVL
SNKPAKGHVA KANTAPKRFI KEFKNVELGE YEVGKEIKVD VFQAGDVVDV TGTTKGKGFQ
GAIKRHGQSR GPMSHGSRYH RRPGSMGPVA PNRVFKNKRL AGRMGGDRVT IQNLEVVKVD
VERNVILIKG NIPGAKKSLI TIKSAVKAK
