RL3_HALSA
ID RL3_HALSA Reviewed; 335 AA.
AC Q9HPD4; Q06844;
DT 16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN Name=rpl3 {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=VNG_1689G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8241282; DOI=10.1016/0167-4781(93)90169-e;
RA Yuki Y., Kanechika R., Itoh T.;
RT "Nucleotide sequence of the genes encoding the L3, L4, and L23 equivalent
RT ribosomal proteins from the archaebacterium Halobacterium halobium.";
RL Biochim. Biophys. Acta 1216:335-338(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L24e. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; AB006961; BAA22270.1; -; Genomic_DNA.
DR EMBL; AE004437; AAG19936.1; -; Genomic_DNA.
DR PIR; D84321; D84321.
DR PIR; T43816; T43816.
DR RefSeq; WP_010903234.1; NC_002607.1.
DR AlphaFoldDB; Q9HPD4; -.
DR SMR; Q9HPD4; -.
DR STRING; 64091.VNG_1689G; -.
DR PaxDb; Q9HPD4; -.
DR EnsemblBacteria; AAG19936; AAG19936; VNG_1689G.
DR GeneID; 5953080; -.
DR GeneID; 62887086; -.
DR KEGG; hal:VNG_1689G; -.
DR PATRIC; fig|64091.14.peg.1288; -.
DR HOGENOM; CLU_033361_2_0_2; -.
DR InParanoid; Q9HPD4; -.
DR OMA; HQRTEYN; -.
DR OrthoDB; 31722at2157; -.
DR PhylomeDB; Q9HPD4; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR Gene3D; 4.10.960.10; -; 1.
DR HAMAP; MF_01325_A; Ribosomal_L3_A; 1.
DR InterPro; IPR045077; L3_arc_euk.
DR InterPro; IPR000597; Ribosomal_L3.
DR InterPro; IPR019928; Ribosomal_L3_arc.
DR InterPro; IPR019926; Ribosomal_L3_CS.
DR InterPro; IPR044892; Ribosomal_L3_dom_3_arc_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11363; PTHR11363; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR03626; L3_arch; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..335
FT /note="50S ribosomal protein L3"
FT /id="PRO_0000077208"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 41
FT /note="G -> A (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 75
FT /note="Missing (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 82..83
FT /note="Missing (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 118..122
FT /note="DEGGD -> TRRV (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 149
FT /note="T -> H (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 198
FT /note="T -> A (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 228..231
FT /note="QGWR -> HVA (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 277
FT /note="T -> S (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
FT CONFLICT 311..312
FT /note="PA -> LG (in Ref. 1; BAA22270)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 335 AA; 36569 MW; 5DAFBF1835DB8673 CRC64;
MPQPNRPRKG SMGFSPRKRA ESEVPRFNSW PADDGEVGLQ GFAGYKAGMT HVVLVDDKAN
APTEGMETTV PVTVVETPPM RAAAVRLYED TPYGKKPLTE VWADDTHESL DRTLSVPDEG
GDTDELIEAL DTEEIADIRV ITHTVPGDTA GVPKKNPDVM ETRVGGGTLA DRLEFAADLI
EDGGVHAFGD VFRAGEFTDA AGITKGKGTQ GPVKRWGVQK RKGKHARQGW RRRIGNLGPW
NPSRVRSTVP QQGQTGYHQR TELNKRLIDI NDGDEPTPDG GFPNYGEVDG PYTLVKGSVP
GPEQRLVRFR PAVRPNESPR LDPEVRYVST ASNQG
