ID   RL3_MYCLE               Reviewed;         217 AA.
AC   P30762; O32981;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 3.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN   Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=ML1863;
GN   ORFNames=MLCB2492.02;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-99.
RX   PubMed=8446028; DOI=10.1111/j.1365-2958.1993.tb01112.x;
RA   Honore N.T., Bergh S., Chanteau S., Doucet-Populaire F., Eiglmeier K.,
RA   Garnier T., Georges C., Launois P., Limpaiboon T., Newton S., Niang K.,
RA   del Portillo P., Ramesh G.R., Reddi P., Ridel P.R., Sittisombut N.,
RA   Wu-Hunter S., Cole S.T.;
RT   "Nucleotide sequence of the first cosmid from the Mycobacterium leprae
RT   genome project: structure and function of the Rif-Str regions.";
RL   Mol. Microbiol. 7:207-214(1993).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC       subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC       proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA78677.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAC30817.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; Z98756; CAB11435.1; -; Genomic_DNA.
DR   EMBL; AL583923; CAC30817.1; ALT_INIT; Genomic_DNA.
DR   EMBL; Z14314; CAA78677.1; ALT_INIT; Genomic_DNA.
DR   PIR; A87142; A87142.
DR   PIR; S31154; S31154.
DR   PIR; T45364; T45364.
DR   RefSeq; WP_041323030.1; NC_002677.1.
DR   AlphaFoldDB; P30762; -.
DR   SMR; P30762; -.
DR   STRING; 272631.ML1863; -.
DR   EnsemblBacteria; CAC30817; CAC30817; CAC30817.
DR   KEGG; mle:ML1863; -.
DR   Leproma; ML1863; -.
DR   eggNOG; COG0087; Bacteria.
DR   HOGENOM; CLU_044142_4_1_11; -.
DR   OMA; KRMAGRY; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01325_B; Ribosomal_L3_B; 1.
DR   InterPro; IPR000597; Ribosomal_L3.
DR   InterPro; IPR019927; Ribosomal_L3_bac/org-type.
DR   InterPro; IPR019926; Ribosomal_L3_CS.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   PANTHER; PTHR11229; PTHR11229; 1.
DR   Pfam; PF00297; Ribosomal_L3; 1.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   TIGRFAMs; TIGR03625; L3_bact; 1.
DR   PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..217
FT                   /note="50S ribosomal protein L3"
FT                   /id="PRO_0000077121"
FT   CONFLICT        44
FT                   /note="R -> P (in Ref. 1; CAB11435)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   217 AA;  23241 MW;  50298ADB0F884C7E CRC64;
     MARKGILGTK LGMTQVFDEN NRVVPVTVVK AGPNVVTRIR TLERDGYSAV QLAYGEISPR
     KVNKPVTGQY NSAGVNPRRY LAELRLDHPD AAAEYEVGQE LTAEIFADAT YVDVTGTSKG
     KGFSGTMKRH GFRGQGASHG AQAVHRRPGS IGGCATPARV FKGTRMAGRM GNDRVTVQNL
     LVHKVDTENG VLLIKGAVPG RTGGLVMVRS AIKRGEK