RL3_MYCS2
ID RL3_MYCS2 Reviewed; 217 AA.
AC A0QSD1; I7FGA9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325};
GN OrderedLocusNames=MSMEG_1436, MSMEI_1400;
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT mutations or sequencing errors?";
RL Genome Biol. 8:R20.1-R20.9(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=18955433; DOI=10.1101/gr.081901.108;
RA Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT and a new MS-based protocol.";
RL Genome Res. 19:128-135(2009).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; CP000480; ABK75373.1; -; Genomic_DNA.
DR EMBL; CP001663; AFP37873.1; -; Genomic_DNA.
DR RefSeq; WP_003892823.1; NZ_SIJM01000016.1.
DR RefSeq; YP_885819.1; NC_008596.1.
DR PDB; 5O60; EM; 3.20 A; D=1-217.
DR PDB; 5O61; EM; 3.31 A; D=1-217.
DR PDB; 5XYM; EM; 3.08 A; D=1-217.
DR PDB; 5ZEB; EM; 3.40 A; D=1-217.
DR PDB; 5ZEP; EM; 3.40 A; D=1-217.
DR PDB; 5ZET; EM; 3.20 A; D=1-217.
DR PDB; 6DZI; EM; 3.46 A; D=2-215.
DR PDB; 6DZP; EM; 3.42 A; D=1-217.
DR PDBsum; 5O60; -.
DR PDBsum; 5O61; -.
DR PDBsum; 5XYM; -.
DR PDBsum; 5ZEB; -.
DR PDBsum; 5ZEP; -.
DR PDBsum; 5ZET; -.
DR PDBsum; 6DZI; -.
DR PDBsum; 6DZP; -.
DR AlphaFoldDB; A0QSD1; -.
DR SMR; A0QSD1; -.
DR IntAct; A0QSD1; 3.
DR STRING; 246196.MSMEI_1400; -.
DR PRIDE; A0QSD1; -.
DR EnsemblBacteria; ABK75373; ABK75373; MSMEG_1436.
DR EnsemblBacteria; AFP37873; AFP37873; MSMEI_1400.
DR GeneID; 66732895; -.
DR KEGG; msg:MSMEI_1400; -.
DR KEGG; msm:MSMEG_1436; -.
DR PATRIC; fig|246196.19.peg.1422; -.
DR eggNOG; COG0087; Bacteria.
DR OMA; KRMAGRY; -.
DR OrthoDB; 1270636at2; -.
DR Proteomes; UP000000757; Chromosome.
DR Proteomes; UP000006158; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01325_B; Ribosomal_L3_B; 1.
DR InterPro; IPR000597; Ribosomal_L3.
DR InterPro; IPR019927; Ribosomal_L3_bac/org-type.
DR InterPro; IPR019926; Ribosomal_L3_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11229; PTHR11229; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR03625; L3_bact; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..217
FT /note="50S ribosomal protein L3"
FT /id="PRO_1000052088"
FT STRAND 5..17
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 23..30
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 34..40
FT /evidence="ECO:0007829|PDB:5XYM"
FT TURN 42..45
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 49..56
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 59..61
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 64..73
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 78..85
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 90..94
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 103..106
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 112..117
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 123..125
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 127..130
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 137..140
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 145..147
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 154..157
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 168..171
FT /evidence="ECO:0007829|PDB:6DZP"
FT STRAND 173..180
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 182..186
FT /evidence="ECO:0007829|PDB:5XYM"
FT TURN 187..190
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 191..196
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 205..210
FT /evidence="ECO:0007829|PDB:5XYM"
FT TURN 212..214
FT /evidence="ECO:0007829|PDB:5O60"
SQ SEQUENCE 217 AA; 22972 MW; 4FBB59BDAB7CEF24 CRC64;
MARKGILGTK LGMTQVFDEN NKVVPVTVVK AGPNVVTRIR TTERDGYSAV QLAYGEISPR
KVIKPVAGQF AAAGVNPRRH VAELRLDDEA AVAEYEVGQE LTAEIFSDGA YVDVTGTSKG
KGFAGTMKRH GFRGQGAAHG AQAVHRRPGS IGGCATPGRV FKGTRMSGRM GNDRVTTQNL
KVHKVDAENG VLLIKGAIPG RNGGLVVVRS AIKRGEK
