ID   RL3_MYCTU               Reviewed;         217 AA.
AC   P9WH87; L0T4G4; O06044; P60442; P95049;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN   Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=Rv0701;
GN   ORFNames=MTCY210.20;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC       subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC       proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR   EMBL; AL123456; CCP43445.1; -; Genomic_DNA.
DR   PIR; H70641; H70641.
DR   RefSeq; NP_215215.1; NC_000962.3.
DR   RefSeq; WP_003403579.1; NZ_NVQJ01000007.1.
DR   PDB; 5V7Q; EM; 3.70 A; D=1-217.
DR   PDB; 7KGB; EM; 2.70 A; D=1-217.
DR   PDB; 7MSC; EM; 2.97 A; D=1-217.
DR   PDB; 7MSH; EM; 3.23 A; D=1-217.
DR   PDB; 7MSM; EM; 2.79 A; D=1-217.
DR   PDB; 7MSZ; EM; 3.10 A; D=1-217.
DR   PDB; 7MT2; EM; 2.76 A; D=1-217.
DR   PDB; 7MT3; EM; 2.80 A; D=1-217.
DR   PDB; 7MT7; EM; 2.71 A; D=1-217.
DR   PDBsum; 5V7Q; -.
DR   PDBsum; 7KGB; -.
DR   PDBsum; 7MSC; -.
DR   PDBsum; 7MSH; -.
DR   PDBsum; 7MSM; -.
DR   PDBsum; 7MSZ; -.
DR   PDBsum; 7MT2; -.
DR   PDBsum; 7MT3; -.
DR   PDBsum; 7MT7; -.
DR   AlphaFoldDB; P9WH87; -.
DR   SMR; P9WH87; -.
DR   STRING; 83332.Rv0701; -.
DR   PaxDb; P9WH87; -.
DR   DNASU; 888343; -.
DR   GeneID; 45424666; -.
DR   GeneID; 888343; -.
DR   KEGG; mtu:Rv0701; -.
DR   TubercuList; Rv0701; -.
DR   eggNOG; COG0087; Bacteria.
DR   OMA; KRMAGRY; -.
DR   PhylomeDB; P9WH87; -.
DR   PRO; PR:P9WH87; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01325_B; Ribosomal_L3_B; 1.
DR   InterPro; IPR000597; Ribosomal_L3.
DR   InterPro; IPR019927; Ribosomal_L3_bac/org-type.
DR   InterPro; IPR019926; Ribosomal_L3_CS.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   PANTHER; PTHR11229; PTHR11229; 1.
DR   Pfam; PF00297; Ribosomal_L3; 1.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   TIGRFAMs; TIGR03625; L3_bact; 1.
DR   PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   RNA-binding; rRNA-binding.
FT   CHAIN           1..217
FT                   /note="50S ribosomal protein L3"
FT                   /id="PRO_0000077125"
SQ   SEQUENCE   217 AA;  23090 MW;  420D4FCD7530FB84 CRC64;
     MARKGILGTK LGMTQVFDES NRVVPVTVVK AGPNVVTRIR TPERDGYSAV QLAYGEISPR
     KVNKPLTGQY TAAGVNPRRY LAELRLDDSD AATEYQVGQE LTAEIFADGS YVDVTGTSKG
     KGFAGTMKRH GFRGQGASHG AQAVHRRPGS IGGCATPARV FKGTRMAGRM GNDRVTVLNL
     LVHKVDAENG VLLIKGAVPG RTGGLVMVRS AIKRGEK