RL3_PYRHO
ID RL3_PYRHO Reviewed; 362 AA.
AC O59418;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN Name=rpl3 {ECO:0000255|HAMAP-Rule:MF_01325}; OrderedLocusNames=PH1777;
GN ORFNames=PHLG003;
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L24e. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; BA000001; BAA30895.1; -; Genomic_DNA.
DR PIR; H71187; H71187.
DR RefSeq; WP_010885842.1; NC_000961.1.
DR AlphaFoldDB; O59418; -.
DR SMR; O59418; -.
DR STRING; 70601.3258212; -.
DR EnsemblBacteria; BAA30895; BAA30895; BAA30895.
DR GeneID; 1442624; -.
DR KEGG; pho:PH1777; -.
DR eggNOG; arCOG04070; Archaea.
DR OMA; HQRTEYN; -.
DR OrthoDB; 31722at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 4.10.960.10; -; 1.
DR HAMAP; MF_01325_A; Ribosomal_L3_A; 1.
DR InterPro; IPR045077; L3_arc_euk.
DR InterPro; IPR000597; Ribosomal_L3.
DR InterPro; IPR019928; Ribosomal_L3_arc.
DR InterPro; IPR019926; Ribosomal_L3_CS.
DR InterPro; IPR044892; Ribosomal_L3_dom_3_arc_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11363; PTHR11363; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR03626; L3_arch; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding.
FT CHAIN 1..362
FT /note="50S ribosomal protein L3"
FT /id="PRO_0000077219"
FT REGION 340..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40815 MW; DA1DDE53004323BE CRC64;
MGKIHRPRKG SLAFSPRKRA KSIVPRIRSW PKETEVRMLG FAGYKAGMTH ILMIDDEPGL
TNGKEIFMPV TIIETPPLRV FGIRAYRQGY LGLETAGEVI VPDFELDNYT PSKKGKGRKF
TFYQFLGRRI ATLPKDYTQE EFEQKLGALE DMIKEGEIVE VRALVSTQPW VIKLKKKPEV
MEYAIGGTSV EEKFNYIKEK LGKEIRVGEV LKEGELLDVI AVTKGKGTQG PVKRWGIKLR
AHKDSKGRRK VGSIGPWHPA RVMWTVPMAG QMGFHHRTEL NKRLIAIGEN GKLVIDGNEI
EITPKGGFPH YGIVRGDFMM IAGSVPGAIK RIIRVRPAIR PPKKKPPVQR PQITYVSVES
KQ
