RL3_STAA8
ID RL3_STAA8 Reviewed; 220 AA.
AC Q2FW06;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=50S ribosomal protein L3 {ECO:0000255|HAMAP-Rule:MF_01325};
GN Name=rplC {ECO:0000255|HAMAP-Rule:MF_01325};
GN OrderedLocusNames=SAOUHSC_02512;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S
CC subunit. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L14 and L19. {ECO:0000255|HAMAP-Rule:MF_01325}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000255|HAMAP-Rule:MF_01325}.
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DR EMBL; CP000253; ABD31530.1; -; Genomic_DNA.
DR RefSeq; WP_000160212.1; NZ_LS483365.1.
DR RefSeq; YP_500979.1; NC_007795.1.
DR PDB; 4WF9; X-ray; 3.43 A; B=1-220.
DR PDB; 4WFA; X-ray; 3.39 A; B=1-220.
DR PDB; 4WFB; X-ray; 3.43 A; B=1-220.
DR PDB; 5HKV; X-ray; 3.66 A; B=1-220.
DR PDB; 5HL7; X-ray; 3.55 A; B=1-220.
DR PDB; 5LI0; EM; 3.80 A; E=2-219.
DR PDB; 5ND8; EM; 3.70 A; E=1-220.
DR PDB; 5ND9; EM; 3.70 A; E=1-220.
DR PDB; 5NRG; X-ray; 3.44 A; B=1-220.
DR PDB; 5TCU; EM; 3.90 A; LC=2-216.
DR PDB; 6DDD; EM; 3.10 A; L=1-217.
DR PDB; 6DDG; EM; 3.10 A; L=1-217.
DR PDB; 6HMA; EM; 2.65 A; D=2-216.
DR PDB; 6SJ6; EM; 3.23 A; E=1-220.
DR PDB; 6WQN; EM; 2.90 A; L=1-217.
DR PDB; 6WQQ; EM; 3.10 A; L=1-217.
DR PDB; 6WRS; EM; 3.20 A; L=1-217.
DR PDB; 6WRU; EM; 3.10 A; L=1-217.
DR PDB; 6YEF; EM; 3.20 A; E=1-220.
DR PDB; 7NHL; EM; 3.10 A; H=1-220.
DR PDB; 7NHM; EM; 3.10 A; H=1-220.
DR PDBsum; 4WF9; -.
DR PDBsum; 4WFA; -.
DR PDBsum; 4WFB; -.
DR PDBsum; 5HKV; -.
DR PDBsum; 5HL7; -.
DR PDBsum; 5LI0; -.
DR PDBsum; 5ND8; -.
DR PDBsum; 5ND9; -.
DR PDBsum; 5NRG; -.
DR PDBsum; 5TCU; -.
DR PDBsum; 6DDD; -.
DR PDBsum; 6DDG; -.
DR PDBsum; 6HMA; -.
DR PDBsum; 6SJ6; -.
DR PDBsum; 6WQN; -.
DR PDBsum; 6WQQ; -.
DR PDBsum; 6WRS; -.
DR PDBsum; 6WRU; -.
DR PDBsum; 6YEF; -.
DR PDBsum; 7NHL; -.
DR PDBsum; 7NHM; -.
DR AlphaFoldDB; Q2FW06; -.
DR SMR; Q2FW06; -.
DR IntAct; Q2FW06; 2.
DR STRING; 1280.SAXN108_2499; -.
DR EnsemblBacteria; ABD31530; ABD31530; SAOUHSC_02512.
DR GeneID; 3920888; -.
DR GeneID; 66840462; -.
DR KEGG; sao:SAOUHSC_02512; -.
DR PATRIC; fig|93061.5.peg.2267; -.
DR eggNOG; COG0087; Bacteria.
DR HOGENOM; CLU_044142_4_1_9; -.
DR OMA; KRMAGRY; -.
DR PRO; PR:Q2FW06; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01325_B; Ribosomal_L3_B; 1.
DR InterPro; IPR000597; Ribosomal_L3.
DR InterPro; IPR019927; Ribosomal_L3_bac/org-type.
DR InterPro; IPR019926; Ribosomal_L3_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11229; PTHR11229; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; SSF50447; 1.
DR TIGRFAMs; TIGR03625; L3_bact; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..220
FT /note="50S ribosomal protein L3"
FT /id="PRO_1000052149"
FT REGION 130..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 5..16
FT /evidence="ECO:0007829|PDB:6HMA"
FT HELIX 18..20
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 22..29
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 34..39
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 41..44
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 48..52
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 57..60
FT /evidence="ECO:0007829|PDB:4WFA"
FT STRAND 65..68
FT /evidence="ECO:0007829|PDB:6HMA"
FT HELIX 71..79
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 85..87
FT /evidence="ECO:0007829|PDB:6WRU"
FT STRAND 88..91
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 96..98
FT /evidence="ECO:0007829|PDB:6WQN"
FT TURN 100..102
FT /evidence="ECO:0007829|PDB:5NRG"
FT HELIX 107..109
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 115..121
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 126..128
FT /evidence="ECO:0007829|PDB:6WQN"
FT HELIX 130..133
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 141..144
FT /evidence="ECO:0007829|PDB:6WQN"
FT STRAND 148..150
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 157..160
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 171..173
FT /evidence="ECO:0007829|PDB:6WQN"
FT STRAND 177..189
FT /evidence="ECO:0007829|PDB:6HMA"
FT TURN 190..193
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 194..199
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 205..207
FT /evidence="ECO:0007829|PDB:4WFB"
FT STRAND 209..213
FT /evidence="ECO:0007829|PDB:6HMA"
SQ SEQUENCE 220 AA; 23718 MW; 27BAE1308C8F0675 CRC64;
MTKGILGRKI GMTQVFGENG ELIPVTVVEA KENVVLQKKT VEVDGYNAIQ VGFEDKKAYK
KDAKSNKYAN KPAEGHAKKA DAAPKRFIRE FRNVDVDAYE VGQEVSVDTF VAGDVIDVTG
VSKGKGFQGA IKRHGQSRGP MSHGSHFHRA PGSVGMASDA SRVFKGQKMP GRMGGNTVTV
QNLEVVQVDT ENKVILVKGN VPGPKKGLVE IRTSIKKGNK
