RL44E_PYRHO
ID RL44E_PYRHO Reviewed; 94 AA.
AC O59603;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2001, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=50S ribosomal protein L44e {ECO:0000255|HAMAP-Rule:MF_01476};
GN Name=rpl44e {ECO:0000255|HAMAP-Rule:MF_01476}; OrderedLocusNames=PH1940;
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000255|HAMAP-Rule:MF_01476}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01476};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000255|HAMAP-Rule:MF_01476};
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01476}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL42 family.
CC {ECO:0000255|HAMAP-Rule:MF_01476}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA31067.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; BA000001; BAA31067.1; ALT_INIT; Genomic_DNA.
DR PIR; D71209; D71209.
DR RefSeq; WP_010886007.1; NC_000961.1.
DR AlphaFoldDB; O59603; -.
DR SMR; O59603; -.
DR STRING; 70601.3258384; -.
DR EnsemblBacteria; BAA31067; BAA31067; BAA31067.
DR GeneID; 1442789; -.
DR KEGG; pho:PH1940; -.
DR eggNOG; arCOG04109; Archaea.
DR OMA; CKKHTIH; -.
DR OrthoDB; 106603at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01476; Ribosomal_L44e; 1.
DR InterPro; IPR000552; Ribosomal_L44e.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR PANTHER; PTHR10369; PTHR10369; 1.
DR Pfam; PF00935; Ribosomal_L44; 1.
DR SUPFAM; SSF57829; SSF57829; 1.
DR PROSITE; PS01172; RIBOSOMAL_L44E; 1.
PE 3: Inferred from homology;
KW Metal-binding; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding; Zinc; Zinc-finger.
FT CHAIN 1..94
FT /note="50S ribosomal protein L44e"
FT /id="PRO_0000149155"
FT ZN_FING 11..74
FT /note="C4-type"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01476"
FT BINDING 11
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01476"
FT BINDING 14
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01476"
FT BINDING 71
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01476"
FT BINDING 74
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01476"
SQ SEQUENCE 94 AA; 11242 MW; 2ACCFA3778674F5B CRC64;
MKYPKQIRTY CPYCKRHTIH KVERVKRRPR SELSAGQRRF RRVLKGYGGF PRPKPEGREK
PVKKLDLRFV CTVCGRAHTR GKGFRVKRFE LVEV
