ID   RL4B_XENLA              Reviewed;         401 AA.
AC   P02385; Q7ZYR6;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 2.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=60S ribosomal protein L4-B;
DE   AltName: Full=L1B;
GN   Name=rpl4-b; Synonyms=rpl1b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-372.
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 6-401.
RX   PubMed=3841512; DOI=10.1002/j.1460-2075.1985.tb04107.x;
RA   Loreni F., Ruberti I., Bozzoni I., Pierandrei-Amaldi P., Amaldi F.;
RT   "Nucleotide sequence of the L1 ribosomal protein gene of Xenopus laevis:
RT   remarkable sequence homology among introns.";
RL   EMBO J. 4:3483-3488(1985).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 291-401.
RX   PubMed=7049839; DOI=10.1016/0378-1119(82)90147-0;
RA   Amaldi F., Beccari E., Bozzoni I., Luo Z.-X., Pierandrei-Amaldi P.;
RT   "Nucleotide sequences of cloned cDNA fragments specific for six Xenopus
RT   laevis ribosomal proteins.";
RL   Gene 17:311-316(1982).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P36578}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P36578}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P36578}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH41744.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR   EMBL; BC041744; AAH41744.1; ALT_SEQ; mRNA.
DR   EMBL; X05217; CAA28844.1; -; mRNA.
DR   EMBL; V01438; CAA24699.1; -; mRNA.
DR   PIR; B24579; R5XL1B.
DR   RefSeq; NP_001082721.1; NM_001089252.2.
DR   AlphaFoldDB; P02385; -.
DR   SMR; P02385; -.
DR   BioGRID; 100008; 1.
DR   DNASU; 398678; -.
DR   GeneID; 398678; -.
DR   KEGG; xla:398678; -.
DR   CTD; 398678; -.
DR   Xenbase; XB-GENE-6255762; rpl4.S.
DR   OMA; WHQKVNV; -.
DR   OrthoDB; 878848at2759; -.
DR   Proteomes; UP000186698; Chromosome 3S.
DR   Bgee; 398678; Expressed in spleen and 19 other tissues.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.40.1370.10; -; 1.
DR   InterPro; IPR025755; Ribos_L4_C_dom.
DR   InterPro; IPR002136; Ribosomal_L4/L1e.
DR   InterPro; IPR013000; Ribosomal_L4/L1e_euk/arc_CS.
DR   InterPro; IPR023574; Ribosomal_L4_dom_sf.
DR   InterPro; IPR045240; Ribosomal_L4_euk/arch.
DR   PANTHER; PTHR19431; PTHR19431; 1.
DR   Pfam; PF14374; Ribos_L4_asso_C; 1.
DR   Pfam; PF00573; Ribosomal_L4; 1.
DR   SUPFAM; SSF52166; SSF52166; 1.
DR   PROSITE; PS00939; RIBOSOMAL_L1E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..401
FT                   /note="60S ribosomal protein L4-B"
FT                   /id="PRO_0000129355"
FT   REGION          351..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        291..294
FT                   /note="TDLT -> LICA (in Ref. 2; CAA24699)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        326
FT                   /note="L -> P (in Ref. 2; CAA24699)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        342..344
FT                   /note="HAI -> MH (in Ref. 2; CAA24699)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        387
FT                   /note="R -> K (in Ref. 2; CAA24699)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   401 AA;  45426 MW;  ABD52BCB70AAA059 CRC64;
     MAVSMACARP LISVYSEKGE TSGKNVTMPA VFKAPIRPDI VNFVHTNLRK NNRQPYAVSK
     LAGHQTSAES WGTGRAVARI PRVRGGGTHR SGQGAFGNMC RGGRMFAPTK TWRRWHRRVN
     TTQKRYAVCS ALAASALPAL IMSKGHRIEE IPEVPLVVED KVESYKKTKE AVLLLKKLKA
     WNDIKKVYAS QRMRAGKGKM RNRRRIQRRG PCVIYNENNG IIKAFRNIPG ITLLNVSKLN
     LLRLAPGGHV GRFCIWTESA FRKLDDLYGT WRKSAKLKAD YNLPMHKMTN TDLTRILKSQ
     EIQRALRAPN KKVKRRELKK NPLKNLRIMM RLNPYAKTAR RHAILQQLEN IKAKEKKPDD
     GKPKAKKPLD AKTKMIKLAK AKKRQARAEA KTAEAKTAES K