RL4_CAEEL
ID RL4_CAEEL Reviewed; 345 AA.
AC O02056;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=60S ribosomal protein L4;
GN Name=rpl-4; ORFNames=B0041.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP PROTEIN SEQUENCE OF 2-22; 29-44; 86-96; 113-119; 140-161; 173-181; 204-218;
RP 222-233; 239-291 AND 328-336, IDENTIFICATION BY MASS SPECTROMETRY, AND
RP ACETYLATION AT ALA-2.
RA Bienvenut W.V.;
RL Submitted (AUG-2005) to UniProtKB.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000305}.
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DR EMBL; FO080106; CCD61249.1; -; Genomic_DNA.
DR PIR; T34031; T34031.
DR RefSeq; NP_491416.1; NM_059015.4.
DR AlphaFoldDB; O02056; -.
DR SMR; O02056; -.
DR BioGRID; 37538; 97.
DR DIP; DIP-26846N; -.
DR IntAct; O02056; 5.
DR STRING; 6239.B0041.4; -.
DR iPTMnet; O02056; -.
DR EPD; O02056; -.
DR PaxDb; O02056; -.
DR PeptideAtlas; O02056; -.
DR EnsemblMetazoa; B0041.4.1; B0041.4.1; WBGene00004415.
DR GeneID; 172074; -.
DR KEGG; cel:CELE_B0041.4; -.
DR UCSC; B0041.4.1; c. elegans.
DR CTD; 172074; -.
DR WormBase; B0041.4; CE07669; WBGene00004415; rpl-4.
DR eggNOG; KOG1475; Eukaryota.
DR GeneTree; ENSGT00390000018145; -.
DR HOGENOM; CLU_026535_4_0_1; -.
DR InParanoid; O02056; -.
DR OMA; WHQKVNV; -.
DR OrthoDB; 878848at2759; -.
DR PhylomeDB; O02056; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:O02056; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00004415; Expressed in larva and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0008340; P:determination of adult lifespan; IMP:WormBase.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.40.1370.10; -; 1.
DR InterPro; IPR025755; Ribos_L4_C_dom.
DR InterPro; IPR002136; Ribosomal_L4/L1e.
DR InterPro; IPR013000; Ribosomal_L4/L1e_euk/arc_CS.
DR InterPro; IPR023574; Ribosomal_L4_dom_sf.
DR InterPro; IPR045240; Ribosomal_L4_euk/arch.
DR PANTHER; PTHR19431; PTHR19431; 1.
DR Pfam; PF14374; Ribos_L4_asso_C; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; SSF52166; 1.
DR PROSITE; PS00939; RIBOSOMAL_L1E; 1.
PE 1: Evidence at protein level;
KW Acetylation; Direct protein sequencing; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|Ref.2"
FT CHAIN 2..345
FT /note="60S ribosomal protein L4"
FT /id="PRO_0000129358"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000269|Ref.2"
SQ SEQUENCE 345 AA; 38659 MW; C798B9DB0CED60AD CRC64;
MAARPLVTVY DEKYEATQSQ IRLPAVFRTP IRPDLVSFIA DQVRRNRRQA HAVNTKAGKQ
HSAESWGTGR AVARIPRVRG GGTHRSGQGA FGNMCRGGHM FAPLKVFRRW HRNVNIAQKR
YAVSSAIAAS GIPALLQARG HVIDQVAEVP LVVSDKVESF RKTKEAVVFL RRSHLWADIE
KVYNSKRNRA GKGKLRNRQH KQKLGPVVIY GQDAECARAF RNIPGVDVMN VERLNLLKLA
PGGHLGRLII WTESAFKKLD TIYGTTVANS SQLKKGWSVP LPIMANSDFS RIIRSEEVVK
AIRAPKKNPV LPKVHRNPLK KRTLLYKLNP YASILRKASK ANVKK