AAU3_RHIME
ID AAU3_RHIME Reviewed; 154 AA.
AC Q9R9M8;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein aau3;
GN Name=aau3; OrderedLocusNames=R00730; ORFNames=SMc00785;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=10735852; DOI=10.1128/jb.182.8.2113-2118.2000;
RA Cai G.-Q., Driscoll B.T., Charles T.C.;
RT "Requirement for the enzymes acetoacetyl coenzyme A synthetase and poly-3-
RT hydroxybutyrate (PHB) synthase for growth of Sinorhizobium meliloti on PHB
RT cycle intermediates.";
RL J. Bacteriol. 182:2113-2118(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Required for growth utilizing PHB cycle intermediates.
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Evidence={ECO:0000250};
CC Note=Binds 1 [2Fe-2S] cluster. {ECO:0000250};
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DR EMBL; AF193764; AAF06014.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45302.1; -; Genomic_DNA.
DR RefSeq; NP_384836.1; NC_003047.1.
DR RefSeq; WP_003527122.1; NC_003047.1.
DR AlphaFoldDB; Q9R9M8; -.
DR SMR; Q9R9M8; -.
DR STRING; 266834.SMc00785; -.
DR EnsemblBacteria; CAC45302; CAC45302; SMc00785.
DR GeneID; 61602197; -.
DR KEGG; sme:SMc00785; -.
DR PATRIC; fig|266834.11.peg.2109; -.
DR eggNOG; COG1959; Bacteria.
DR HOGENOM; CLU_107144_2_1_5; -.
DR OMA; LRMLMYC; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR030489; TR_Rrf2-type_CS.
DR InterPro; IPR000944; Tscrpt_reg_Rrf2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33221; PTHR33221; 1.
DR Pfam; PF02082; Rrf2; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR TIGRFAMs; TIGR00738; rrf2_super; 1.
DR PROSITE; PS01332; HTH_RRF2_1; 1.
DR PROSITE; PS51197; HTH_RRF2_2; 1.
PE 3: Inferred from homology;
KW 2Fe-2S; DNA-binding; Iron; Iron-sulfur; Metal-binding; Reference proteome.
FT CHAIN 1..154
FT /note="Protein aau3"
FT /id="PRO_0000036203"
FT DOMAIN 2..132
FT /note="HTH rrf2-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT BINDING 91
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT BINDING 99
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT BINDING 105
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00540"
FT CONFLICT 32
FT /note="R -> G (in Ref. 1; AAF06014)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 154 AA; 17013 MW; FCF18CEE6D5FE41F CRC64;
MRLTKQTNYA VRMLMYCAAN GEKLSRIPEI ARAYGVSELF LFKILQPLTR AGLVETVRGR
NGGVRLPRPA SEITLFDVVK VTEDSFAMAE CFEAGEIDCP LVDSCGLNAA LRKALNAFFE
VLQGYTIDDL VKARPQINFL LGLEEPVRPQ TSAA
