ID   RL4_LEPIN               Reviewed;         211 AA.
AC   Q9XD35;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=50S ribosomal protein L4 {ECO:0000255|HAMAP-Rule:MF_01328};
GN   Name=rplD {ECO:0000255|HAMAP-Rule:MF_01328}; OrderedLocusNames=LA_0740;
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain
OS   56601).
OC   Bacteria; Spirochaetes; Leptospirales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=189518;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Lai / Serogroup Icterohaemorrhagiae / Serovar lai;
RX   PubMed=10620683; DOI=10.1111/j.1574-6968.2000.tb08912.x;
RA   Zuerner R.L., Hartskeerl R.A., van de Kemp H., Bal A.E.;
RT   "Characterization of the Leptospira interrogans S10-spc-alpha operon.";
RL   FEMS Microbiol. Lett. 182:303-308(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=56601;
RX   PubMed=12712204; DOI=10.1038/nature01597;
RA   Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X.,
RA   Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X.,
RA   Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H., Yin H.-F., Zhang Y., Zhu G.-F.,
RA   Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y.,
RA   Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I.,
RA   Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P.;
RT   "Unique physiological and pathogenic features of Leptospira interrogans
RT   revealed by whole-genome sequencing.";
RL   Nature 422:888-893(2003).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC       initially binds near the 5'-end of the 23S rRNA. It is important during
CC       the early stages of 50S assembly. It makes multiple contacts with
CC       different domains of the 23S rRNA in the assembled 50S subunit and
CC       ribosome. {ECO:0000255|HAMAP-Rule:MF_01328}.
CC   -!- FUNCTION: Forms part of the polypeptide exit tunnel.
CC       {ECO:0000255|HAMAP-Rule:MF_01328}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_01328}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01328}.
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DR   EMBL; AF115283; AAD40584.1; -; Genomic_DNA.
DR   EMBL; AE010300; AAN47939.1; -; Genomic_DNA.
DR   RefSeq; NP_710921.1; NC_004342.2.
DR   RefSeq; WP_000647275.1; NC_004342.2.
DR   AlphaFoldDB; Q9XD35; -.
DR   SMR; Q9XD35; -.
DR   STRING; 189518.LA_0740; -.
DR   PRIDE; Q9XD35; -.
DR   EnsemblBacteria; AAN47939; AAN47939; LA_0740.
DR   GeneID; 61142746; -.
DR   KEGG; lil:LA_0740; -.
DR   PATRIC; fig|189518.3.peg.744; -.
DR   HOGENOM; CLU_041575_5_2_12; -.
DR   InParanoid; Q9XD35; -.
DR   OMA; PQVHILE; -.
DR   Proteomes; UP000001408; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1370.10; -; 1.
DR   HAMAP; MF_01328_B; Ribosomal_L4_B; 1.
DR   InterPro; IPR002136; Ribosomal_L4/L1e.
DR   InterPro; IPR023574; Ribosomal_L4_dom_sf.
DR   InterPro; IPR013005; Ribosomal_uL4/L1e.
DR   PANTHER; PTHR10746; PTHR10746; 1.
DR   Pfam; PF00573; Ribosomal_L4; 1.
DR   SUPFAM; SSF52166; SSF52166; 1.
DR   TIGRFAMs; TIGR03953; rplD_bact; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..211
FT                   /note="50S ribosomal protein L4"
FT                   /id="PRO_0000129231"
FT   REGION          46..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   211 AA;  23326 MW;  EF500C5A91E5D1C5 CRC64;
     MKAQKYSKEG KLISEIELPS ALFESKLSVA SIYEAIKAEN ANLRSGNHAT KTRSMVSGGG
     KKPWSQKGTG RARQGSTRAP HWVGGGTVHG PQKRDYSYKV SSKLKHRAVL SILGKKAQAS
     AVKVVEDLDP KEYNTKAFDS IFKNMNLKNT GVIGLLVQGE NDFLKKSVRN IPTVKYINSK
     RISCRDILYN RNLVITEAAL KEMLVQYGAQ K