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RL4_PSEAE
ID   RL4_PSEAE               Reviewed;         200 AA.
AC   Q9HWD6;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=50S ribosomal protein L4;
GN   Name=rplD; OrderedLocusNames=PA4262;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   DOES NOT REGULATE THE E.COLI S10 OPERON.
RX   PubMed=10498727; DOI=10.1128/jb.181.19.6124-6132.1999;
RA   Allen T., Shen P., Samsel L., Liu R., Lindahl L., Zengel J.M.;
RT   "Phylogenetic analysis of L4-mediated autogenous control of the S10
RT   ribosomal protein operon.";
RL   J. Bacteriol. 181:6124-6132(1999).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC       initially binds near the 5'-end of the 23S rRNA. It is important during
CC       the early stages of 50S assembly. It makes multiple contacts with
CC       different domains of the 23S rRNA in the assembled 50S subunit and
CC       ribosome (By similarity). {ECO:0000250}.
CC   -!- FUNCTION: The P.aeruginosa S10 leader is not regulated by the E.coli L4
CC       protein. This and other data strongly suggest the S10 operon is
CC       regulated differently than in E.coli.
CC   -!- FUNCTION: Forms part of the polypeptide exit tunnel. {ECO:0000250}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG07650.1; -; Genomic_DNA.
DR   PIR; D83116; D83116.
DR   RefSeq; NP_252952.1; NC_002516.2.
DR   RefSeq; WP_003093737.1; NZ_QZGE01000028.1.
DR   AlphaFoldDB; Q9HWD6; -.
DR   SMR; Q9HWD6; -.
DR   STRING; 287.DR97_3649; -.
DR   PaxDb; Q9HWD6; -.
DR   PRIDE; Q9HWD6; -.
DR   DNASU; 881754; -.
DR   EnsemblBacteria; AAG07650; AAG07650; PA4262.
DR   GeneID; 881754; -.
DR   KEGG; pae:PA4262; -.
DR   PATRIC; fig|208964.12.peg.4463; -.
DR   PseudoCAP; PA4262; -.
DR   HOGENOM; CLU_041575_5_2_6; -.
DR   InParanoid; Q9HWD6; -.
DR   OMA; PQVHILE; -.
DR   PhylomeDB; Q9HWD6; -.
DR   BioCyc; PAER208964:G1FZ6-4335-MON; -.
DR   PRO; PR:Q9HWD6; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.1370.10; -; 1.
DR   HAMAP; MF_01328_B; Ribosomal_L4_B; 1.
DR   InterPro; IPR002136; Ribosomal_L4/L1e.
DR   InterPro; IPR023574; Ribosomal_L4_dom_sf.
DR   InterPro; IPR013005; Ribosomal_uL4/L1e.
DR   PANTHER; PTHR10746; PTHR10746; 1.
DR   Pfam; PF00573; Ribosomal_L4; 1.
DR   SUPFAM; SSF52166; SSF52166; 1.
DR   TIGRFAMs; TIGR03953; rplD_bact; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..200
FT                   /note="50S ribosomal protein L4"
FT                   /id="PRO_0000129259"
FT   REGION          38..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   200 AA;  21640 MW;  E285F29A5673D558 CRC64;
     MQLNVNGAQA IEVSERTFGG EFNETLVHQA VVAYMAGGRQ GSKAQKTRSE VSGGGKKPWR
     QKGTGRARAG TIRSPIWRGG GTTFAAKPRS HEQKLNKKMY RAALRSILAE LVRLDRLVVV
     ADFAVDAPKT KGLVAKLDTL GLKDVLIVTD GVDENLYLAA RNLAHVDVRD VQGSDPVSLI
     AYDKVLVTVS AVKKFEELLG
 
 
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