RL4_THEKO
ID RL4_THEKO Reviewed; 255 AA.
AC Q5JDI0;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=50S ribosomal protein L4 {ECO:0000255|HAMAP-Rule:MF_01328};
GN Name=rpl4 {ECO:0000255|HAMAP-Rule:MF_01328}; OrderedLocusNames=TK1541;
OS Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Pyrococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon Thermococcus
RT kodakaraensis KOD1 and comparison with Pyrococcus genomes.";
RL Genome Res. 15:352-363(2005).
CC -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC initially binds near the 5'-end of the 23S rRNA. It is important during
CC the early stages of 50S assembly. It makes multiple contacts with
CC different domains of the 23S rRNA in the assembled 50S subunit and
CC ribosome. {ECO:0000255|HAMAP-Rule:MF_01328}.
CC -!- FUNCTION: Forms part of the polypeptide exit tunnel.
CC {ECO:0000255|HAMAP-Rule:MF_01328}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01328}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000255|HAMAP-Rule:MF_01328}.
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DR EMBL; AP006878; BAD85730.1; -; Genomic_DNA.
DR RefSeq; WP_011250492.1; NC_006624.1.
DR PDB; 6SKF; EM; 2.95 A; BE=1-255.
DR PDB; 6SKG; EM; 2.65 A; BE=1-255.
DR PDB; 6TH6; EM; 2.55 A; BE=1-255.
DR PDBsum; 6SKF; -.
DR PDBsum; 6SKG; -.
DR PDBsum; 6TH6; -.
DR AlphaFoldDB; Q5JDI0; -.
DR SMR; Q5JDI0; -.
DR STRING; 69014.TK1541; -.
DR EnsemblBacteria; BAD85730; BAD85730; TK1541.
DR GeneID; 3235328; -.
DR KEGG; tko:TK1541; -.
DR PATRIC; fig|69014.16.peg.1501; -.
DR eggNOG; arCOG04071; Archaea.
DR HOGENOM; CLU_026535_0_0_2; -.
DR InParanoid; Q5JDI0; -.
DR OMA; WHQKVNV; -.
DR OrthoDB; 65833at2157; -.
DR PhylomeDB; Q5JDI0; -.
DR Proteomes; UP000000536; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1370.10; -; 1.
DR HAMAP; MF_01328_A; Ribosomal_L4_A; 1.
DR InterPro; IPR002136; Ribosomal_L4/L1e.
DR InterPro; IPR013000; Ribosomal_L4/L1e_euk/arc_CS.
DR InterPro; IPR023574; Ribosomal_L4_dom_sf.
DR InterPro; IPR045240; Ribosomal_L4_euk/arch.
DR InterPro; IPR019970; Ribosomall_L4-archaea.
DR PANTHER; PTHR19431; PTHR19431; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; SSF52166; 1.
DR TIGRFAMs; TIGR03672; rpl4p_arch; 1.
DR PROSITE; PS00939; RIBOSOMAL_L1E; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..255
FT /note="50S ribosomal protein L4"
FT /id="PRO_0000129342"
SQ SEQUENCE 255 AA; 28712 MW; 693FD461AF57739A CRC64;
MKVKVFNLEG EPVEEIELPK VFSTPFRPDL IRRAVIASWT HRIQPQGRDP QAGKRRVTEN
IGKGHGMARV ERIKTSPRFA AFVPFAVGGR RTHPPKVEKI IWEDINKKER RLAIMSAIAA
TANYDLVRAR GHVVDNVVQI PLVVTDDLQK VFKTAQTREI FKKLGVWDDI ERAKKNTKIR
AGKGKMRGRR YKKAKGPLIV VAKNEGIVQG ARNHPGVDVV TVDNLGVEYL APGTHPGRLT
IWTKGAIERL REIYG
