ID   AAXA_CHLFF              Reviewed;         444 AA.
AC   Q255H9;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Porin AaxA;
DE   AltName: Full=Outer membrane protein AaxA;
DE   Flags: Precursor;
GN   Name=aaxA; OrderedLocusNames=CF0287;
OS   Chlamydia felis (strain Fe/C-56) (Chlamydophila felis).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=264202;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fe/C-56;
RX   PubMed=16766509; DOI=10.1093/dnares/dsi027;
RA   Azuma Y., Hirakawa H., Yamashita A., Cai Y., Rahman M.A., Suzuki H.,
RA   Mitaku S., Toh H., Goto S., Murakami T., Sugi K., Hayashi H., Fukushi H.,
RA   Hattori M., Kuhara S., Shirai M.;
RT   "Genome sequence of the cat pathogen, Chlamydophila felis.";
RL   DNA Res. 13:15-23(2006).
CC   -!- FUNCTION: Facilitates L-arginine uptake, as part of the AaxABC system.
CC       The arginine uptake by the bacterium in the macrophage may be a
CC       virulence factor against the host innate immune response (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OprB family. {ECO:0000305}.
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DR   EMBL; AP006861; BAE81059.1; -; Genomic_DNA.
DR   RefSeq; WP_011457840.1; NC_007899.1.
DR   AlphaFoldDB; Q255H9; -.
DR   STRING; 264202.89331466; -.
DR   KEGG; cfe:BAE81059.1; -.
DR   eggNOG; COG3659; Bacteria.
DR   HOGENOM; CLU_619231_0_0_0; -.
DR   OMA; SQTFPGD; -.
DR   OrthoDB; 338964at2; -.
DR   Proteomes; UP000001260; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.160.180; -; 1.
DR   InterPro; IPR007049; Carb-sel_porin_OprB.
DR   InterPro; IPR038673; OprB_sf.
DR   Pfam; PF04966; OprB; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell outer membrane; Ion transport; Membrane; Porin;
KW   Signal; Transmembrane; Transmembrane beta strand; Transport; Virulence.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..444
FT                   /note="Porin AaxA"
FT                   /id="PRO_0000363180"
FT   REGION          42..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   444 AA;  49332 MW;  B1DDD8F43FC72557 CRC64;
     MAFSRFYLLT ALYTGGILAS SAYGIPSNYP EHHHRLIERL KKNSTQDSDS SPSESSPHPR
     QEPRRHVLTP VHNVLKDRPC DEGLSISKLL HSIEKETNSQ ISVDFTILPQ WFYPKKAALA
     TVDEKQPTWQ FYISPNVSWQ LYNSPTAGVG SIDFSYTLIR YWRNSAQNAN NAAGIAGGIN
     DYSSRTNTLS QLTFSQTFPG DILTVAMGQY SLYSIDGTLY DNDQQSGFIS YALSQNASAT
     YSLGSVGAYV QFTPTPSINI QAGFQDAYNI VGTSFDVYNL TKNKYNFYGY FSWAPQCKLG
     NGQYSALIYS TRKVPQQPTQ TTGWSLNFGQ HLGEKLYVFG RWNGATGTAI NLNRSYVLGL
     ASANPINRNS QDLLGAACSI SKVNPKVVTE KRIRKYETVI ETFATIGFGP HISLTPDLQI
     YIHPALRPDK RSAKVYGVRA NFSA