RL5_HALMT
ID RL5_HALMT Reviewed; 172 AA.
AC P50557; I3R7P6;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2012, sequence version 2.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=50S ribosomal protein L5 {ECO:0000255|HAMAP-Rule:MF_01333};
DE AltName: Full=HmeL5;
GN Name=rpl5 {ECO:0000255|HAMAP-Rule:MF_01333}; OrderedLocusNames=HFX_2575;
OS Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC
OS 14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=523841;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4;
RX PubMed=22843593; DOI=10.1128/jb.00880-12;
RA Han J., Zhang F., Hou J., Liu X., Li M., Liu H., Cai L., Zhang B., Chen Y.,
RA Zhou J., Hu S., Xiang H.;
RT "Complete genome sequence of the metabolically versatile halophilic
RT archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-
RT hydroxyvalerate) producer.";
RL J. Bacteriol. 194:4463-4464(2012).
RN [2]
RP PROTEIN SEQUENCE OF 2-22.
RC STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4;
RX PubMed=8174557; DOI=10.1111/j.1432-1033.1994.tb18791.x;
RA McDougall J., Wittmann-Liebold B.;
RT "Comparative analysis of the protein components from 5S rRNA.protein
RT complexes of halophilic archaebacteria.";
RL Eur. J. Biochem. 221:779-785(1994).
CC -!- FUNCTION: This is 1 of the proteins that binds and probably mediates
CC the attachment of the 5S RNA into the large ribosomal subunit, where it
CC forms part of the central protuberance. In the 70S ribosome it contacts
CC protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits;
CC this bridge is implicated in subunit movement. May contact the P site
CC tRNA; the 5S rRNA and some of its associated proteins might help
CC stabilize positioning of ribosome-bound tRNAs. {ECO:0000255|HAMAP-
CC Rule:MF_01333}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit; contacts the 5S rRNA and
CC probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_01333}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL5 family.
CC {ECO:0000255|HAMAP-Rule:MF_01333}.
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DR EMBL; CP001868; AFK20256.1; -; Genomic_DNA.
DR PIR; G33084; G33084.
DR RefSeq; WP_004060022.1; NZ_CP039139.1.
DR AlphaFoldDB; P50557; -.
DR SMR; P50557; -.
DR STRING; 523841.HFX_2575; -.
DR EnsemblBacteria; AFK20256; AFK20256; HFX_2575.
DR GeneID; 40157532; -.
DR KEGG; hme:HFX_2575; -.
DR eggNOG; arCOG04092; Archaea.
DR HOGENOM; CLU_061015_3_0_2; -.
DR OMA; ERMYAFL; -.
DR OrthoDB; 97230at2157; -.
DR Proteomes; UP000006469; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1440.10; -; 1.
DR HAMAP; MF_01333_A; Ribosomal_L5_A; 1.
DR InterPro; IPR002132; Ribosomal_L5.
DR InterPro; IPR022804; Ribosomal_L5_arc.
DR InterPro; IPR031309; Ribosomal_L5_C.
DR InterPro; IPR022803; Ribosomal_L5_dom_sf.
DR InterPro; IPR031310; Ribosomal_L5_N.
DR PANTHER; PTHR11994; PTHR11994; 1.
DR Pfam; PF00281; Ribosomal_L5; 1.
DR Pfam; PF00673; Ribosomal_L5_C; 1.
DR PIRSF; PIRSF002161; Ribosomal_L5; 1.
DR SUPFAM; SSF55282; SSF55282; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; tRNA-binding.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8174557"
FT CHAIN 2..172
FT /note="50S ribosomal protein L5"
FT /id="PRO_0000125052"
SQ SEQUENCE 172 AA; 19122 MW; 1D083DDE2C35805E CRC64;
MSEAEFHEMR DPRIEKVVVH MGVGEGGREL AKSEDILEEI TGQESVRTIS GRASQDFGVR
QGEPVGAKVT LRGESAVEFL ETALPITDLS ASSFDETGNF GFGVEEHTEF PSQEYDPQIG
IYGLDVTVNI VRPGYRVKKR DKRSRQIPSS HRMTVEDAVA FIESTFDVEV EE
