RL5_PYRHO
ID RL5_PYRHO Reviewed; 188 AA.
AC O59431;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=50S ribosomal protein L5 {ECO:0000255|HAMAP-Rule:MF_01333};
GN Name=rpl5 {ECO:0000255|HAMAP-Rule:MF_01333}; OrderedLocusNames=PH1765;
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- FUNCTION: This is 1 of the proteins that binds and probably mediates
CC the attachment of the 5S RNA into the large ribosomal subunit, where it
CC forms part of the central protuberance. In the 70S ribosome it contacts
CC protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits;
CC this bridge is implicated in subunit movement. May contact the P site
CC tRNA; the 5S rRNA and some of its associated proteins might help
CC stabilize positioning of ribosome-bound tRNAs. {ECO:0000255|HAMAP-
CC Rule:MF_01333}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit; contacts the 5S rRNA and
CC probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
CC {ECO:0000255|HAMAP-Rule:MF_01333}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL5 family.
CC {ECO:0000255|HAMAP-Rule:MF_01333}.
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DR EMBL; BA000001; BAA30880.1; -; Genomic_DNA.
DR PIR; A71186; A71186.
DR RefSeq; WP_010885827.1; NC_000961.1.
DR AlphaFoldDB; O59431; -.
DR SMR; O59431; -.
DR STRING; 70601.3258197; -.
DR EnsemblBacteria; BAA30880; BAA30880; BAA30880.
DR GeneID; 1442609; -.
DR KEGG; pho:PH1765; -.
DR eggNOG; arCOG04092; Archaea.
DR OMA; ERMYAFL; -.
DR OrthoDB; 97230at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1440.10; -; 1.
DR HAMAP; MF_01333_A; Ribosomal_L5_A; 1.
DR InterPro; IPR002132; Ribosomal_L5.
DR InterPro; IPR022804; Ribosomal_L5_arc.
DR InterPro; IPR031309; Ribosomal_L5_C.
DR InterPro; IPR022803; Ribosomal_L5_dom_sf.
DR InterPro; IPR031310; Ribosomal_L5_N.
DR PANTHER; PTHR11994; PTHR11994; 1.
DR Pfam; PF00281; Ribosomal_L5; 1.
DR Pfam; PF00673; Ribosomal_L5_C; 1.
DR PIRSF; PIRSF002161; Ribosomal_L5; 1.
DR SUPFAM; SSF55282; SSF55282; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding;
KW tRNA-binding.
FT CHAIN 1..188
FT /note="50S ribosomal protein L5"
FT /id="PRO_0000125066"
SQ SEQUENCE 188 AA; 21610 MW; 56CAF0B5053AECF4 CRC64;
MPVSIPNREE ILADWEAHPM RRPRIQKVTI NIGVGESGER LTKAEIMLQR LTGQKPIRRK
AKKTNRDFGI RRGEPIAVKV TLRGPKAYEM LKRLLAAVDY KLKASSFDEH GNVCFGIEEH
INIPGVEYDP EIGIFGMDVC VTLERPGFRV ARRKRKRARI PTRHKLTKEE GMLYMMEEFG
VEIVEEEG
