ID   RL6_CHILA               Reviewed;         288 AA.
AC   Q6QMZ4;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=60S ribosomal protein L6;
GN   Name=RPL6;
OS   Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha;
OC   Chinchillidae; Chinchilla.
OX   NCBI_TaxID=34839;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Middle ear mucosa;
RA   Erdos G., Hu F.Z., Donfack J., Ahmed A.I., Preston R.A., Hayes J.D.,
RA   Post J.C., Ehrlich G.D.;
RT   "Gene expression in normal chinchilla middle ear mucosa.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:Q02878}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit (By similarity). May
CC       bind IPO9 with low affinity (By similarity).
CC       {ECO:0000250|UniProtKB:P47911, ECO:0000250|UniProtKB:Q02878}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q02878}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q02878}. Rough endoplasmic reticulum
CC       {ECO:0000250|UniProtKB:Q2YGT9}. Note=Detected on cytosolic polysomes
CC       (By similarity). Detected in ribosomes that are associated with the
CC       rough endoplasmic reticulum (By similarity).
CC       {ECO:0000250|UniProtKB:Q02878, ECO:0000250|UniProtKB:Q2YGT9}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL6 family.
CC       {ECO:0000305}.
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DR   EMBL; AY533226; AAS59428.1; -; mRNA.
DR   RefSeq; NP_001269292.1; NM_001282363.1.
DR   AlphaFoldDB; Q6QMZ4; -.
DR   SMR; Q6QMZ4; -.
DR   PRIDE; Q6QMZ4; -.
DR   GeneID; 102027037; -.
DR   CTD; 6128; -.
DR   OrthoDB; 1227453at2759; -.
DR   Proteomes; UP000694398; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0042788; C:polysomal ribosome; ISS:UniProtKB.
DR   GO; GO:0005791; C:rough endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   CDD; cd13156; KOW_RPL6; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   InterPro; IPR000915; 60S_ribosomal_L6E.
DR   InterPro; IPR041997; KOW_RPL6.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR005568; Ribosomal_L6_N.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR10715; PTHR10715; 1.
DR   Pfam; PF01159; Ribosomal_L6e; 1.
DR   Pfam; PF03868; Ribosomal_L6e_N; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
DR   PROSITE; PS01170; RIBOSOMAL_L6E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Endoplasmic reticulum; Isopeptide bond; Phosphoprotein;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; Ubl conjugation.
FT   CHAIN           1..288
FT                   /note="60S ribosomal protein L6"
FT                   /id="PRO_0000171008"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         94
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P47911"
FT   MOD_RES         127
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q02878"
FT   MOD_RES         207
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P47911"
FT   CROSSLNK        5
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q02878"
SQ   SEQUENCE   288 AA;  32615 MW;  A84834B2D1D968A8 CRC64;
     MAGEKTEKPD AKEKKPEAKK AVAAGTAKKA NVKAKKSKKG QPHCSRNPVL VRGIGRYSRS
     AMYSRKALYK RKYTAAKSKV EKKKKEKVLA TVTKPVGGDK NGGTRVVKLR KMPRYYPTED
     VPRKLLSHGK KPFSQHVRKL RASITPGTVL IILTGRHRGK RVVFLKQLAS GLLLVTGPLN
     LNRVPLRRTH QKFVIATSTK IDISNVKIPK HLTDAYFKKK KLRKPRHQEG EIFDTEKERY
     QISEQRKVDQ KAVDSQILPK IKAVPQLRGY LRSVFALTNG IYPHKLVF