RL6_ENTFA
ID RL6_ENTFA Reviewed; 178 AA.
AC Q839E9;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=50S ribosomal protein L6 {ECO:0000255|HAMAP-Rule:MF_01365};
GN Name=rplF {ECO:0000255|HAMAP-Rule:MF_01365}; OrderedLocusNames=EF_0221;
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583;
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its
CC secondary structure. It is located near the subunit interface in the
CC base of the L7/L12 stalk, and near the tRNA binding site of the
CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01365}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000255|HAMAP-Rule:MF_01365}.
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DR EMBL; AE016830; AAO80090.1; -; Genomic_DNA.
DR RefSeq; NP_814019.1; NC_004668.1.
DR RefSeq; WP_002379228.1; NZ_KE136524.1.
DR PDB; 6WU9; EM; 2.90 A; G=2-177.
DR PDB; 7P7Q; EM; 2.40 A; K=1-178.
DR PDB; 7P7R; EM; 2.90 A; K=1-178.
DR PDB; 7P7S; EM; 3.00 A; K=1-178.
DR PDB; 7P7T; EM; 2.90 A; K=1-178.
DR PDB; 7P7U; EM; 3.10 A; K=1-178.
DR PDBsum; 6WU9; -.
DR PDBsum; 7P7Q; -.
DR PDBsum; 7P7R; -.
DR PDBsum; 7P7S; -.
DR PDBsum; 7P7T; -.
DR PDBsum; 7P7U; -.
DR AlphaFoldDB; Q839E9; -.
DR SMR; Q839E9; -.
DR STRING; 226185.EF_0221; -.
DR EnsemblBacteria; AAO80090; AAO80090; EF_0221.
DR KEGG; efa:EF0221; -.
DR PATRIC; fig|226185.45.peg.45; -.
DR eggNOG; COG0097; Bacteria.
DR HOGENOM; CLU_065464_1_2_9; -.
DR OMA; KPDPYKG; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.930.12; -; 2.
DR HAMAP; MF_01365_B; Ribosomal_L6_B; 1.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR019906; Ribosomal_L6_bac-type.
DR InterPro; IPR002358; Ribosomal_L6_CS.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR PANTHER; PTHR11655:SF14; PTHR11655:SF14; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR PRINTS; PR00059; RIBOSOMALL6.
DR SUPFAM; SSF56053; SSF56053; 2.
DR TIGRFAMs; TIGR03654; L6_bact; 1.
DR PROSITE; PS00525; RIBOSOMAL_L6_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..178
FT /note="50S ribosomal protein L6"
FT /id="PRO_0000260865"
FT TURN 4..6
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 16..20
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 23..27
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 39..41
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 46..48
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 59..62
FT /evidence="ECO:0007829|PDB:6WU9"
FT HELIX 63..80
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 83..87
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 95..99
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 102..111
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 113..116
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 127..129
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 131..136
FT /evidence="ECO:0007829|PDB:6WU9"
FT HELIX 138..148
FT /evidence="ECO:0007829|PDB:6WU9"
FT STRAND 156..158
FT /evidence="ECO:0007829|PDB:6WU9"
SQ SEQUENCE 178 AA; 19409 MW; 3A54E8A201238C8E CRC64;
MSRIGNKVVV LPAGVEIKQD GNNITVKGPK GELTREFSSD IKMNIEGNEV TFIRPNDSKE
MKTIHGTTRA NFNNMVVGVS EGFQKALELI GVGYRAQVQG NKLTLNVGYS HPVEMTAPEG
VTFEVPANTQ VIVKGINKEV VGELAANIRG VRPPEPYKGK GIRYVGEFVR RKEGKTGK
