RL6_MYCS2
ID RL6_MYCS2 Reviewed; 179 AA.
AC A0QSG4; I7FY99;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=50S ribosomal protein L6 {ECO:0000255|HAMAP-Rule:MF_01365};
GN Name=rplF {ECO:0000255|HAMAP-Rule:MF_01365};
GN OrderedLocusNames=MSMEG_1470, MSMEI_1434;
OS Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=246196;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RA Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA Fraser C.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT mutations or sequencing errors?";
RL Genome Biol. 8:R20.1-R20.9(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 700084 / mc(2)155;
RX PubMed=18955433; DOI=10.1101/gr.081901.108;
RA Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT and a new MS-based protocol.";
RL Genome Res. 19:128-135(2009).
CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its
CC secondary structure. It is located near the subunit interface in the
CC base of the L7/L12 stalk, and near the tRNA binding site of the
CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01365}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000255|HAMAP-Rule:MF_01365}.
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DR EMBL; CP000480; ABK73224.1; -; Genomic_DNA.
DR EMBL; CP001663; AFP37907.1; -; Genomic_DNA.
DR RefSeq; WP_003892857.1; NZ_SIJM01000016.1.
DR RefSeq; YP_885852.1; NC_008596.1.
DR PDB; 5O60; EM; 3.20 A; G=1-179.
DR PDB; 5O61; EM; 3.31 A; G=1-179.
DR PDB; 5XYM; EM; 3.08 A; G=1-179.
DR PDB; 5ZEB; EM; 3.40 A; G=1-179.
DR PDB; 5ZEP; EM; 3.40 A; G=1-179.
DR PDB; 5ZET; EM; 3.20 A; G=1-179.
DR PDB; 6DZI; EM; 3.46 A; G=2-177.
DR PDB; 6DZP; EM; 3.42 A; G=1-179.
DR PDBsum; 5O60; -.
DR PDBsum; 5O61; -.
DR PDBsum; 5XYM; -.
DR PDBsum; 5ZEB; -.
DR PDBsum; 5ZEP; -.
DR PDBsum; 5ZET; -.
DR PDBsum; 6DZI; -.
DR PDBsum; 6DZP; -.
DR AlphaFoldDB; A0QSG4; -.
DR SMR; A0QSG4; -.
DR IntAct; A0QSG4; 3.
DR STRING; 246196.MSMEI_1434; -.
DR PRIDE; A0QSG4; -.
DR EnsemblBacteria; ABK73224; ABK73224; MSMEG_1470.
DR EnsemblBacteria; AFP37907; AFP37907; MSMEI_1434.
DR GeneID; 66732927; -.
DR KEGG; msg:MSMEI_1434; -.
DR KEGG; msm:MSMEG_1470; -.
DR PATRIC; fig|246196.19.peg.1455; -.
DR eggNOG; COG0097; Bacteria.
DR OMA; KPDPYKG; -.
DR OrthoDB; 1398618at2; -.
DR Proteomes; UP000000757; Chromosome.
DR Proteomes; UP000006158; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.930.12; -; 2.
DR HAMAP; MF_01365_B; Ribosomal_L6_B; 1.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR019906; Ribosomal_L6_bac-type.
DR InterPro; IPR002358; Ribosomal_L6_CS.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR PANTHER; PTHR11655:SF14; PTHR11655:SF14; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR PRINTS; PR00059; RIBOSOMALL6.
DR SUPFAM; SSF56053; SSF56053; 2.
DR TIGRFAMs; TIGR03654; L6_bact; 1.
DR PROSITE; PS00525; RIBOSOMAL_L6_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..179
FT /note="50S ribosomal protein L6"
FT /id="PRO_1000055266"
FT TURN 3..6
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 17..19
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 22..25
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 33..35
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 42..45
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 49..54
FT /evidence="ECO:0007829|PDB:5ZET"
FT HELIX 60..81
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 84..90
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 92..96
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 101..103
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 107..112
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 114..116
FT /evidence="ECO:0007829|PDB:5ZET"
FT STRAND 123..128
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 131..137
FT /evidence="ECO:0007829|PDB:5XYM"
FT HELIX 139..150
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 157..159
FT /evidence="ECO:0007829|PDB:5XYM"
FT STRAND 162..164
FT /evidence="ECO:0007829|PDB:5XYM"
SQ SEQUENCE 179 AA; 19453 MW; 1668D25BBD493EA5 CRC64;
MSRIGKQPVP VPSGVDVTIN GQNLSVKGPK GTLTLDVAEP ISVSRAEDGA IVVTRPDDER
RSRSLHGLSR TLIANLVTGV TEGYTQKMEI FGVGYRVQLK GQNLEFALGY SHPVLIEAPE
GITFAVESPT KFSVSGIDKQ KVGQISAVIR RLRRPDPYKG KGVRYEGEQI RRKVGKTGK
