RL6_PYRFU
ID RL6_PYRFU Reviewed; 184 AA.
AC Q8U015;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=50S ribosomal protein L6 {ECO:0000255|HAMAP-Rule:MF_01365};
DE AltName: Full=Large ribosomal subunit protein uL6;
GN Name=rpl6 {ECO:0000255|HAMAP-Rule:MF_01365}; OrderedLocusNames=PF1808;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
RN [2] {ECO:0007744|PDB:4V6U}
RP STRUCTURE BY ELECTRON MICROSCOPY (6.60 ANGSTROMS) IN THE 70S RIBOSOME, AND
RP SUBUNIT.
RX PubMed=23222135; DOI=10.1093/nar/gks1259;
RA Armache J.P., Anger A.M., Marquez V., Franckenberg S., Frohlich T.,
RA Villa E., Berninghausen O., Thomm M., Arnold G.J., Beckmann R.,
RA Wilson D.N.;
RT "Promiscuous behaviour of archaeal ribosomal proteins: implications for
RT eukaryotic ribosome evolution.";
RL Nucleic Acids Res. 41:1284-1293(2013).
CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its
CC secondary structure. It is located near the subunit interface in the
CC base of the L7/L12 stalk, and near the tRNA binding site of the
CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01365, ECO:0000269|PubMed:23222135}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000255|HAMAP-Rule:MF_01365}.
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DR EMBL; AE009950; AAL81932.1; -; Genomic_DNA.
DR RefSeq; WP_011012949.1; NZ_CP023154.1.
DR PDB; 4V4N; EM; 9.00 A; F=1-184.
DR PDB; 4V6U; EM; 6.60 A; BF=1-184.
DR PDBsum; 4V4N; -.
DR PDBsum; 4V6U; -.
DR AlphaFoldDB; Q8U015; -.
DR SMR; Q8U015; -.
DR STRING; 186497.PF1808; -.
DR PRIDE; Q8U015; -.
DR EnsemblBacteria; AAL81932; AAL81932; PF1808.
DR GeneID; 41713627; -.
DR KEGG; pfu:PF1808; -.
DR PATRIC; fig|186497.12.peg.1879; -.
DR eggNOG; arCOG04090; Archaea.
DR HOGENOM; CLU_065464_0_0_2; -.
DR OMA; VFQDGIY; -.
DR OrthoDB; 80629at2157; -.
DR PhylomeDB; Q8U015; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.930.12; -; 2.
DR HAMAP; MF_01365_A; Ribosomal_L6_A; 1.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR002359; Ribosomal_L6_CS2.
DR InterPro; IPR019907; Ribosomal_L6P_arc.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR SUPFAM; SSF56053; SSF56053; 2.
DR TIGRFAMs; TIGR03653; uL6_arch; 1.
DR PROSITE; PS00700; RIBOSOMAL_L6_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..184
FT /note="50S ribosomal protein L6"
FT /id="PRO_0000260996"
SQ SEQUENCE 184 AA; 20860 MW; D04668790BE75787 CRC64;
MPVDAWIREE VEIPEGVEVT VEGYKVKVKG PKGELEREFF WPGIQIFTED GNVVIYKDFP
RRKDVAIART FAAHIRNMIK GVTEGFTYKL KVVYSHFPIS VKVQGDEVII ENFLGEKAPR
KAKILPGVTV KVRGQEIIVE GIDKEAVGQT AANIEQATRI TKWDRRIFQD GIYIVEKAGK
PITF
