RL6_STAA8
ID RL6_STAA8 Reviewed; 178 AA.
AC Q2FW21;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=50S ribosomal protein L6 {ECO:0000255|HAMAP-Rule:MF_01365};
GN Name=rplF {ECO:0000255|HAMAP-Rule:MF_01365};
GN OrderedLocusNames=SAOUHSC_02496;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its
CC secondary structure. It is located near the subunit interface in the
CC base of the L7/L12 stalk, and near the tRNA binding site of the
CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01365}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000255|HAMAP-Rule:MF_01365}.
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DR EMBL; CP000253; ABD31515.1; -; Genomic_DNA.
DR RefSeq; WP_000091975.1; NZ_LS483365.1.
DR RefSeq; YP_500964.1; NC_007795.1.
DR PDB; 4WCE; X-ray; 3.53 A; E=1-178.
DR PDB; 4WF9; X-ray; 3.43 A; E=1-178.
DR PDB; 4WFA; X-ray; 3.39 A; E=1-178.
DR PDB; 4WFB; X-ray; 3.43 A; E=1-178.
DR PDB; 5HKV; X-ray; 3.66 A; E=1-178.
DR PDB; 5HL7; X-ray; 3.55 A; E=1-178.
DR PDB; 5LI0; EM; 3.80 A; H=8-171.
DR PDB; 5ND8; EM; 3.70 A; H=1-178.
DR PDB; 5ND9; EM; 3.70 A; H=1-178.
DR PDB; 5NRG; X-ray; 3.44 A; E=1-178.
DR PDB; 5TCU; EM; 3.90 A; LL=2-175.
DR PDB; 6HMA; EM; 2.65 A; G=2-176.
DR PDB; 6WRU; EM; 3.10 A; U=1-175.
DR PDB; 6YEF; EM; 3.20 A; H=1-178.
DR PDB; 7NHL; EM; 3.10 A; K=1-178.
DR PDB; 7NHM; EM; 3.10 A; K=1-178.
DR PDBsum; 4WCE; -.
DR PDBsum; 4WF9; -.
DR PDBsum; 4WFA; -.
DR PDBsum; 4WFB; -.
DR PDBsum; 5HKV; -.
DR PDBsum; 5HL7; -.
DR PDBsum; 5LI0; -.
DR PDBsum; 5ND8; -.
DR PDBsum; 5ND9; -.
DR PDBsum; 5NRG; -.
DR PDBsum; 5TCU; -.
DR PDBsum; 6HMA; -.
DR PDBsum; 6WRU; -.
DR PDBsum; 6YEF; -.
DR PDBsum; 7NHL; -.
DR PDBsum; 7NHM; -.
DR AlphaFoldDB; Q2FW21; -.
DR SMR; Q2FW21; -.
DR IntAct; Q2FW21; 2.
DR STRING; 1280.SAXN108_2485; -.
DR EnsemblBacteria; ABD31515; ABD31515; SAOUHSC_02496.
DR GeneID; 3920873; -.
DR KEGG; sao:SAOUHSC_02496; -.
DR PATRIC; fig|93061.5.peg.2252; -.
DR eggNOG; COG0097; Bacteria.
DR HOGENOM; CLU_065464_1_2_9; -.
DR OMA; KPDPYKG; -.
DR PRO; PR:Q2FW21; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR Gene3D; 3.90.930.12; -; 2.
DR HAMAP; MF_01365_B; Ribosomal_L6_B; 1.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR019906; Ribosomal_L6_bac-type.
DR InterPro; IPR002358; Ribosomal_L6_CS.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR PANTHER; PTHR11655:SF14; PTHR11655:SF14; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR PRINTS; PR00059; RIBOSOMALL6.
DR SUPFAM; SSF56053; SSF56053; 2.
DR TIGRFAMs; TIGR03654; L6_bact; 1.
DR PROSITE; PS00525; RIBOSOMAL_L6_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..178
FT /note="50S ribosomal protein L6"
FT /id="PRO_0000265303"
FT TURN 3..5
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 14..19
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 21..28
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 33..36
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 42..48
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 50..53
FT /evidence="ECO:0007829|PDB:6HMA"
FT HELIX 59..80
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 83..91
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 95..99
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 102..111
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 113..115
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 122..136
FT /evidence="ECO:0007829|PDB:6HMA"
FT HELIX 138..149
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 156..158
FT /evidence="ECO:0007829|PDB:6HMA"
FT STRAND 161..164
FT /evidence="ECO:0007829|PDB:6HMA"
SQ SEQUENCE 178 AA; 19787 MW; 62A50C86B3689C40 CRC64;
MSRVGKKIID IPSDVTVTFD GNHVTVKGPK GELSRTLNER MTFKQEENTI EVVRPSDSKE
DRTNHGTTRA LLNNMVQGVS QGYVKVLELV GVGYRAQMQG KDLILNVGYS HPVEIKAEEN
ITFSVEKNTV VKVEGISKEQ VGALASNIRS VRPPEPYKGK GIRYQGEYVR RKEGKTGK
