RL6_THET2
ID RL6_THET2 Reviewed; 180 AA.
AC Q72I19;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=50S ribosomal protein L6 {ECO:0000255|HAMAP-Rule:MF_01365};
GN Name=rplF {ECO:0000255|HAMAP-Rule:MF_01365}; OrderedLocusNames=TT_C1313;
OS Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27).
OC Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=262724;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-163 / DSM 7039 / HB27;
RX PubMed=15064768; DOI=10.1038/nbt956;
RA Henne A., Brueggemann H., Raasch C., Wiezer A., Hartsch T., Liesegang H.,
RA Johann A., Lienard T., Gohl O., Martinez-Arias R., Jacobi C.,
RA Starkuviene V., Schlenczeck S., Dencker S., Huber R., Klenk H.-P.,
RA Kramer W., Merkl R., Gottschalk G., Fritz H.-J.;
RT "The genome sequence of the extreme thermophile Thermus thermophilus.";
RL Nat. Biotechnol. 22:547-553(2004).
CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its
CC secondary structure. It is located near the subunit interface in the
CC base of the L7/L12 stalk, and near the tRNA binding site of the
CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01365}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000255|HAMAP-Rule:MF_01365}.
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DR EMBL; AE017221; AAS81655.1; -; Genomic_DNA.
DR RefSeq; WP_011173704.1; NC_005835.1.
DR PDB; 4V4I; X-ray; 3.71 A; F=1-180.
DR PDB; 4V4J; X-ray; 3.83 A; F=1-180.
DR PDB; 4V63; X-ray; 3.21 A; BH/DH=1-180.
DR PDB; 4V67; X-ray; 3.00 A; BH/DH=1-180.
DR PDB; 4V7P; X-ray; 3.62 A; BG/CG=1-180.
DR PDB; 4V83; X-ray; 3.50 A; BG/DG=12-170.
DR PDB; 4V84; X-ray; 3.40 A; BG/DG=12-170.
DR PDB; 4V9J; X-ray; 3.86 A; BH/DH=12-178.
DR PDB; 4V9K; X-ray; 3.50 A; BH/DH=12-178.
DR PDB; 4V9L; X-ray; 3.50 A; BH/DH=12-178.
DR PDB; 4V9M; X-ray; 4.00 A; BH/DH=12-178.
DR PDB; 4V9N; X-ray; 3.40 A; BH/DH=12-170.
DR PDB; 4V9Q; X-ray; 3.40 A; AH/CH=12-170.
DR PDB; 4W29; X-ray; 3.80 A; BH/DH=12-178.
DR PDB; 4XEJ; X-ray; 3.80 A; AL06/BL06=12-170.
DR PDB; 5J4D; X-ray; 3.10 A; I/NB=1-180.
DR PDBsum; 4V4I; -.
DR PDBsum; 4V4J; -.
DR PDBsum; 4V63; -.
DR PDBsum; 4V67; -.
DR PDBsum; 4V7P; -.
DR PDBsum; 4V83; -.
DR PDBsum; 4V84; -.
DR PDBsum; 4V9J; -.
DR PDBsum; 4V9K; -.
DR PDBsum; 4V9L; -.
DR PDBsum; 4V9M; -.
DR PDBsum; 4V9N; -.
DR PDBsum; 4V9Q; -.
DR PDBsum; 4W29; -.
DR PDBsum; 4XEJ; -.
DR PDBsum; 5J4D; -.
DR AlphaFoldDB; Q72I19; -.
DR SMR; Q72I19; -.
DR IntAct; Q72I19; 4.
DR STRING; 262724.TT_C1313; -.
DR EnsemblBacteria; AAS81655; AAS81655; TT_C1313.
DR GeneID; 3169807; -.
DR KEGG; tth:TT_C1313; -.
DR eggNOG; COG0097; Bacteria.
DR HOGENOM; CLU_065464_1_2_0; -.
DR OMA; KPDPYKG; -.
DR OrthoDB; 1398618at2; -.
DR EvolutionaryTrace; Q72I19; -.
DR Proteomes; UP000000592; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.930.12; -; 2.
DR HAMAP; MF_01365_B; Ribosomal_L6_B; 1.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR019906; Ribosomal_L6_bac-type.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR PANTHER; PTHR11655:SF14; PTHR11655:SF14; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR PRINTS; PR00059; RIBOSOMALL6.
DR SUPFAM; SSF56053; SSF56053; 2.
DR TIGRFAMs; TIGR03654; L6_bact; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..180
FT /note="50S ribosomal protein L6"
FT /id="PRO_0000260969"
FT STRAND 16..19
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 21..23
FT /evidence="ECO:0007829|PDB:4V9L"
FT STRAND 25..27
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 32..34
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 39..41
FT /evidence="ECO:0007829|PDB:4V9K"
FT STRAND 42..44
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 47..50
FT /evidence="ECO:0007829|PDB:4V9N"
FT STRAND 51..53
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 55..57
FT /evidence="ECO:0007829|PDB:4V9Q"
FT HELIX 59..80
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 83..85
FT /evidence="ECO:0007829|PDB:4V63"
FT STRAND 88..93
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 95..99
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 102..111
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 113..115
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 121..127
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 130..136
FT /evidence="ECO:0007829|PDB:4V67"
FT HELIX 138..151
FT /evidence="ECO:0007829|PDB:4V67"
FT STRAND 156..159
FT /evidence="ECO:0007829|PDB:4V84"
FT STRAND 161..163
FT /evidence="ECO:0007829|PDB:4V67"
SQ SEQUENCE 180 AA; 19532 MW; 1913833C0C30E95D CRC64;
MSRIGRLPIP VPKGVSVEVA PGRVKVKGPK GELEVPVSPE MRVVVEEGVV RVERPSDERR
HKSLHGLTRT LIANAVKGVS EGYSKELLIK GIGYRARLVG RALELTVGFS HPVVVEPPEG
ITFEVPEPTR VRVSGIDKQK VGQVAANIRA IRKPSAYHEK GIYYAGEPVR LKPGKAGAKK
