RL7A_ARCFU
ID RL7A_ARCFU Reviewed; 119 AA.
AC O29494;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=50S ribosomal protein L7Ae {ECO:0000255|HAMAP-Rule:MF_00326};
DE AltName: Full=Ribosomal protein L8e {ECO:0000255|HAMAP-Rule:MF_00326};
GN Name=rpl7ae {ECO:0000255|HAMAP-Rule:MF_00326}; OrderedLocusNames=AF_0764;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
RN [2]
RP FUNCTION.
RX PubMed=12560482; DOI=10.1093/nar/gkg175;
RA Rozhdestvensky T.S., Tang T.H., Tchirkova I.V., Brosius J.,
RA Bachellerie J.-P., Huettenhofer A.;
RT "Binding of L7Ae protein to the K-turn of archaeal snoRNAs: a shared RNA
RT binding motif for C/D and H/ACA box snoRNAs in Archaea.";
RL Nucleic Acids Res. 31:869-877(2003).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS).
RX PubMed=15130473; DOI=10.1016/j.str.2004.02.033;
RA Moore T., Zhang Y., Fenley M.O., Li H.;
RT "Molecular basis of box C/D RNA-protein interactions; cocrystal structure
RT of archaeal L7Ae and a box C/D RNA.";
RL Structure 12:807-818(2004).
CC -!- FUNCTION: Multifunctional RNA-binding protein that recognizes the K-
CC turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA,
CC box C/D and box C'/D' sRNAs. {ECO:0000255|HAMAP-Rule:MF_00326,
CC ECO:0000269|PubMed:12560482}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Probably part of the RNase
CC P complex. {ECO:0000255|HAMAP-Rule:MF_00326}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00326}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000255|HAMAP-Rule:MF_00326}.
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DR EMBL; AE000782; AAB90466.1; -; Genomic_DNA.
DR PIR; D69345; D69345.
DR RefSeq; WP_010878267.1; NC_000917.1.
DR PDB; 1RLG; X-ray; 2.70 A; A/B=1-119.
DR PDB; 4BW0; X-ray; 2.33 A; B=2-119.
DR PDB; 4C4W; X-ray; 2.95 A; C/G=2-119.
DR PDB; 5FJ4; X-ray; 2.95 A; C/G=5-119.
DR PDB; 5G4U; X-ray; 2.65 A; C/D/G/H/K/L=2-119.
DR PDB; 5G4V; X-ray; 2.87 A; C/D/G/H=2-119.
DR PDB; 6HCT; X-ray; 3.09 A; C/D/G=2-117.
DR PDB; 6Q8U; X-ray; 1.99 A; C/D=2-119.
DR PDBsum; 1RLG; -.
DR PDBsum; 4BW0; -.
DR PDBsum; 4C4W; -.
DR PDBsum; 5FJ4; -.
DR PDBsum; 5G4U; -.
DR PDBsum; 5G4V; -.
DR PDBsum; 6HCT; -.
DR PDBsum; 6Q8U; -.
DR AlphaFoldDB; O29494; -.
DR SMR; O29494; -.
DR STRING; 224325.AF_0764; -.
DR EnsemblBacteria; AAB90466; AAB90466; AF_0764.
DR GeneID; 24794362; -.
DR KEGG; afu:AF_0764; -.
DR eggNOG; arCOG01751; Archaea.
DR HOGENOM; CLU_084513_4_0_2; -.
DR OMA; KPFYVRF; -.
DR OrthoDB; 114541at2157; -.
DR PhylomeDB; O29494; -.
DR EvolutionaryTrace; O29494; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:InterPro.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1330.30; -; 1.
DR HAMAP; MF_00326; Ribosomal_L7Ae_Arch; 1.
DR InterPro; IPR029064; L30e-like.
DR InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR InterPro; IPR022481; Ribosomal_L7Ae_arc.
DR InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR InterPro; IPR000948; Ribosomal_L7Ae_prok.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00884; RIBOSOMALHS6.
DR SUPFAM; SSF55315; SSF55315; 1.
DR TIGRFAMs; TIGR03677; eL8_ribo; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; rRNA-binding; tRNA processing.
FT CHAIN 1..119
FT /note="50S ribosomal protein L7Ae"
FT /id="PRO_0000136789"
FT HELIX 9..22
FT /evidence="ECO:0007829|PDB:6Q8U"
FT TURN 23..25
FT /evidence="ECO:0007829|PDB:6Q8U"
FT STRAND 26..31
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 32..40
FT /evidence="ECO:0007829|PDB:6Q8U"
FT STRAND 45..50
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 56..58
FT /evidence="ECO:0007829|PDB:6Q8U"
FT TURN 59..61
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 62..69
FT /evidence="ECO:0007829|PDB:6Q8U"
FT STRAND 73..77
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 79..85
FT /evidence="ECO:0007829|PDB:6Q8U"
FT STRAND 93..99
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 101..103
FT /evidence="ECO:0007829|PDB:6Q8U"
FT HELIX 104..117
FT /evidence="ECO:0007829|PDB:6Q8U"
SQ SEQUENCE 119 AA; 13193 MW; 9065A83C82207501 CRC64;
MYVRFEVPED MQNEALSLLE KVRESGKVKK GTNETTKAVE RGLAKLVYIA EDVDPPEIVA
HLPLLCEEKN VPYIYVKSKN DLGRAVGIEV PCASAAIINE GELRKELGSL VEKIKGLQK
