RL7A_CHICK
ID RL7A_CHICK Reviewed; 266 AA.
AC P32429; Q78DL4;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=60S ribosomal protein L7a;
GN Name=RPL7A; Synonyms=SURF-3;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Liver;
RX PubMed=1631131; DOI=10.1073/pnas.89.14.6358;
RA Colombo P., Yon J., Garson K., Fried M.;
RT "Conservation of the organization of five tightly clustered genes over 600
RT million years of divergent evolution.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:6358-6362(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Liver;
RX PubMed=8274530; DOI=10.1016/0300-9084(93)90128-f;
RA Maeda N., Kenmochi N., Tanaka T.;
RT "The complete nucleotide sequence of chicken ribosomal protein L7a gene and
RT the multiple factor binding sites in its 5'-flanking region.";
RL Biochimie 75:785-790(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Liver;
RA Maeda N., Toku S., Kenmochi N., Tanaka T.;
RT "The gene cluster containing ribosomal protein L7a gene of the chicken.";
RL Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P62424}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P62424}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62424}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000305}.
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DR EMBL; X62640; CAA44506.1; -; mRNA.
DR EMBL; D14522; BAA03395.1; -; Genomic_DNA.
DR EMBL; AB050009; BAC65169.1; -; Genomic_DNA.
DR PIR; A46032; S18159.
DR RefSeq; NP_001004379.1; NM_001004379.1.
DR AlphaFoldDB; P32429; -.
DR SMR; P32429; -.
DR BioGRID; 678553; 1.
DR STRING; 9031.ENSGALP00000038463; -.
DR PaxDb; P32429; -.
DR GeneID; 417158; -.
DR KEGG; gga:417158; -.
DR CTD; 6130; -.
DR VEuPathDB; HostDB:geneid_417158; -.
DR eggNOG; KOG3166; Eukaryota.
DR HOGENOM; CLU_055193_0_1_1; -.
DR InParanoid; P32429; -.
DR OrthoDB; 1200503at2759; -.
DR PhylomeDB; P32429; -.
DR PRO; PR:P32429; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR029064; L30e-like.
DR InterPro; IPR001921; Ribosomal_L7A/L8.
DR InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00882; RIBOSOMALL7A.
DR SUPFAM; SSF55315; SSF55315; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..266
FT /note="60S ribosomal protein L7a"
FT /id="PRO_0000136751"
FT REGION 104..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 266 AA; 30000 MW; 07F5FF5B399ADE65 CRC64;
MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY
IRLQRQRSIL YKRLKVPPAI NQFSQALDRQ TATQLLKLAH KYRPETKQEK KQRLLARAEQ
KAAGKGDTPT KRPPVLRAGV NTVTTLVENK KAQLVVIAHD VDPIELVVFL PALCRKMGVP
YCIIKSKARL GRLVHRKTCT CVAFTQVNPE DKGALAKLVE AVKTNYNDRY DEIRRHWGGN
VLGPKSVARI AKLEKAKAKE LATKLG