ID   RL7A_METJA              Reviewed;         117 AA.
AC   P54066;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   25-MAY-2022, entry version 133.
DE   RecName: Full=50S ribosomal protein L7Ae {ECO:0000255|HAMAP-Rule:MF_00326};
DE   AltName: Full=Ribosomal protein L8e {ECO:0000255|HAMAP-Rule:MF_00326};
GN   Name=rpl7ae {ECO:0000255|HAMAP-Rule:MF_00326}; OrderedLocusNames=MJ1203;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), AND RNA-BINDING.
RX   PubMed=15130481; DOI=10.1016/j.str.2004.03.015;
RA   Hamma T., Ferre-D'Amare A.R.;
RT   "Structure of protein L7Ae bound to a K-turn derived from an archaeal box
RT   H/ACA sRNA at 1.8 A resolution.";
RL   Structure 12:893-903(2004).
RN   [3]
RP   X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).
RX   PubMed=16008351; DOI=10.1021/bi050568q;
RA   Suryadi J., Tran E.J., Maxwell E.S., Brown B.A. II;
RT   "The crystal structure of the Methanocaldococcus jannaschii multifunctional
RT   L7Ae RNA-binding protein reveals an induced-fit interaction with the box
RT   C/D RNAs.";
RL   Biochemistry 44:9657-9672(2005).
CC   -!- FUNCTION: Multifunctional RNA-binding protein that recognizes the K-
CC       turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA,
CC       box C/D and box C'/D' sRNAs.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Probably part of the RNase
CC       P complex. {ECO:0000255|HAMAP-Rule:MF_00326}.
CC   -!- INTERACTION:
CC       P54066; Q58105: MJ0694; NbExp=4; IntAct=EBI-2944269, EBI-2944259;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00326}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00326}.
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DR   EMBL; L77117; AAB99207.1; -; Genomic_DNA.
DR   RefSeq; WP_010870715.1; NC_000909.1.
DR   PDB; 1RA4; X-ray; 1.86 A; A=1-117.
DR   PDB; 1SDS; X-ray; 1.80 A; A/B/C=1-117.
DR   PDB; 1XBI; X-ray; 1.45 A; A=1-117.
DR   PDB; 3PAF; X-ray; 1.70 A; A/B=1-117.
DR   PDB; 6K0A; EM; 4.60 A; I/J=1-117.
DR   PDB; 6K0B; EM; 4.30 A; I/J=1-117.
DR   PDBsum; 1RA4; -.
DR   PDBsum; 1SDS; -.
DR   PDBsum; 1XBI; -.
DR   PDBsum; 3PAF; -.
DR   PDBsum; 6K0A; -.
DR   PDBsum; 6K0B; -.
DR   AlphaFoldDB; P54066; -.
DR   SMR; P54066; -.
DR   IntAct; P54066; 2.
DR   STRING; 243232.MJ_1203; -.
DR   MoonProt; P54066; -.
DR   EnsemblBacteria; AAB99207; AAB99207; MJ_1203.
DR   GeneID; 1452098; -.
DR   KEGG; mja:MJ_1203; -.
DR   eggNOG; arCOG01751; Archaea.
DR   HOGENOM; CLU_084513_4_0_2; -.
DR   InParanoid; P54066; -.
DR   OMA; KPFYVRF; -.
DR   OrthoDB; 114541at2157; -.
DR   PhylomeDB; P54066; -.
DR   EvolutionaryTrace; P54066; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0031428; C:box C/D RNP complex; IMP:CAFA.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0034512; F:box C/D RNA binding; IMP:CAFA.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000492; P:box C/D snoRNP assembly; IMP:CAFA.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   HAMAP; MF_00326; Ribosomal_L7Ae_Arch; 1.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR   InterPro; IPR022481; Ribosomal_L7Ae_arc.
DR   InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR   InterPro; IPR000948; Ribosomal_L7Ae_prok.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00881; L7ARS6FAMILY.
DR   PRINTS; PR00884; RIBOSOMALHS6.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   TIGRFAMs; TIGR03677; eL8_ribo; 1.
DR   PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; RNA-binding; rRNA-binding; tRNA processing.
FT   CHAIN           1..117
FT                   /note="50S ribosomal protein L7Ae"
FT                   /id="PRO_0000136793"
FT   HELIX           11..22
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   STRAND          25..30
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   HELIX           31..39
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   STRAND          44..50
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   HELIX           55..57
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   TURN            58..60
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   HELIX           61..67
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   STRAND          72..76
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   HELIX           78..84
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   STRAND          92..98
FT                   /evidence="ECO:0007829|PDB:1XBI"
FT   HELIX           102..115
FT                   /evidence="ECO:0007829|PDB:1XBI"
SQ   SEQUENCE   117 AA;  12686 MW;  7CAB706F09371BA6 CRC64;
     MAVYVKFKVP EEIQKELLDA VAKAQKIKKG ANEVTKAVER GIAKLVIIAE DVKPEEVVAH
     LPYLCEEKGI PYAYVASKQD LGKAAGLEVA ASSVAIINEG DAEELKVLIE KVNVLKQ