RL7_BOVIN
ID RL7_BOVIN Reviewed; 248 AA.
AC Q58DT1;
DT 02-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=60S ribosomal protein L7;
GN Name=RPL7;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. Binds to G-rich structures in 28S rRNA and in
CC mRNAs. Plays a regulatory role in the translation apparatus; inhibits
CC cell-free translation of mRNAs. {ECO:0000250|UniProtKB:P18124}.
CC -!- SUBUNIT: Component of the large ribosomal subunit. Homodimer. Interacts
CC with DHX33. {ECO:0000250|UniProtKB:P18124}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P18124}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL30 family.
CC {ECO:0000305}.
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DR EMBL; BT021516; AAX46363.1; -; mRNA.
DR RefSeq; NP_001014928.1; NM_001014928.1.
DR AlphaFoldDB; Q58DT1; -.
DR SMR; Q58DT1; -.
DR STRING; 9913.ENSBTAP00000026826; -.
DR PaxDb; Q58DT1; -.
DR PeptideAtlas; Q58DT1; -.
DR PRIDE; Q58DT1; -.
DR Ensembl; ENSBTAT00000026826; ENSBTAP00000026826; ENSBTAG00000020139.
DR GeneID; 514966; -.
DR KEGG; bta:514966; -.
DR CTD; 6129; -.
DR VEuPathDB; HostDB:ENSBTAG00000020139; -.
DR eggNOG; KOG3184; Eukaryota.
DR GeneTree; ENSGT00950000182878; -.
DR HOGENOM; CLU_055156_0_2_1; -.
DR InParanoid; Q58DT1; -.
DR OMA; TKKTNHF; -.
DR OrthoDB; 1544778at2759; -.
DR TreeFam; TF300740; -.
DR Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000020139; Expressed in adenohypophysis and 104 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR CDD; cd01657; Ribosomal_L7_archeal_euk; 1.
DR Gene3D; 3.30.1390.20; -; 2.
DR InterPro; IPR036919; L30_ferredoxin-like_sf.
DR InterPro; IPR018038; Ribosomal_L30_CS.
DR InterPro; IPR016082; Ribosomal_L30_ferredoxin-like.
DR InterPro; IPR012988; Ribosomal_L30_N.
DR InterPro; IPR039699; Ribosomal_L7/L30.
DR InterPro; IPR005998; Ribosomal_L7_euk.
DR InterPro; IPR035808; Ribosomal_L7_euk_arc.
DR PANTHER; PTHR11524; PTHR11524; 1.
DR Pfam; PF00327; Ribosomal_L30; 1.
DR Pfam; PF08079; Ribosomal_L30_N; 1.
DR SUPFAM; SSF55129; SSF55129; 1.
DR TIGRFAMs; TIGR01310; uL30_euk; 1.
DR PROSITE; PS00634; RIBOSOMAL_L30; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Cytoplasm; Phosphoprotein; Reference proteome; Repeat;
KW Ribonucleoprotein; Ribosomal protein; RNA-binding.
FT CHAIN 1..248
FT /note="60S ribosomal protein L7"
FT /id="PRO_0000104632"
FT REPEAT 7..18
FT /note="1"
FT REPEAT 19..30
FT /note="2"
FT REPEAT 31..42
FT /note="3"
FT REPEAT 43..54
FT /note="4"
FT REGION 7..54
FT /note="4 X 12 AA tandem repeats"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:P18124"
FT MOD_RES 17
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P18124"
FT MOD_RES 124
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P18124"
FT MOD_RES 127
FT /note="N6-succinyllysine"
FT /evidence="ECO:0000250|UniProtKB:P14148"
FT MOD_RES 139
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:P18124"
SQ SEQUENCE 248 AA; 29169 MW; 726EBD36287D9284 CRC64;
MEGAEEKKKK VPAVPETLKK KRKNFAELKI KRLRKKFAQK MLRKARRKLI YEKAKHYHKE
YRQMYRTEIR MARMARKAGN FYVPAEPKLA FVIRIRGING VSPKVRKVLQ LLRLRQIFNG
TFVKLNKASI NMLRIVEPYI AWGYPNLKSV NELIYKRGYG KINKKRIALT DNALIARSLG
KYGIICMEDL IHEIYTVGKR FKEANNFLWP FKLSSPRGGM KKKTTHFVEG GDAGNREDQI
NRLIRRMN
