RL7_DICDI
ID RL7_DICDI Reviewed; 246 AA.
AC P11874; Q551I9; Q8T2I4;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 3.
DT 25-MAY-2022, entry version 129.
DE RecName: Full=60S ribosomal protein L7;
GN Name=rpl7; ORFNames=DDB_G0276441;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=AX2;
RX PubMed=2762135; DOI=10.1093/nar/17.13.5393;
RA Szymkowski D.E., Kelly B., Deering R.A.;
RT "A Dictyostelium discoideum cDNA coding for a protein with homology to the
RT rat ribosomal protein L7.";
RL Nucleic Acids Res. 17:5393-5393(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1975664; DOI=10.1093/nar/18.16.4695;
RA Szymkowski D.E., Deering R.A.;
RT "Identification and characterization of a Dictyostelium discoideum
RT ribosomal protein gene.";
RL Nucleic Acids Res. 18:4695-4701(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [5]
RP PROTEIN SEQUENCE OF 5-20; 72-92; 112-122; 133-155; 165-175; 201-215 AND
RP 223-244, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=AX2;
RA Bienvenut W.V., Ura S., Insall R.H.;
RL Submitted (JUL-2009) to UniProtKB.
CC -!- FUNCTION: Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a
CC regulatory role in the translation apparatus; inhibits cell-free
CC translation of mRNAs (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL30 family.
CC {ECO:0000305}.
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DR EMBL; X14909; CAA33035.1; -; mRNA.
DR EMBL; AAFI02000015; EAL69174.1; -; Genomic_DNA.
DR PIR; S04849; R5DO7.
DR RefSeq; XP_643145.1; XM_638053.1.
DR AlphaFoldDB; P11874; -.
DR SMR; P11874; -.
DR STRING; 44689.DDB0185073; -.
DR PaxDb; P11874; -.
DR EnsemblProtists; EAL69174; EAL69174; DDB_G0276441.
DR GeneID; 8620552; -.
DR KEGG; ddi:DDB_G0276441; -.
DR dictyBase; DDB_G0276441; rpl7.
DR eggNOG; KOG3184; Eukaryota.
DR HOGENOM; CLU_055156_0_2_1; -.
DR InParanoid; P11874; -.
DR OMA; TKKTNHF; -.
DR PhylomeDB; P11874; -.
DR Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:P11874; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR CDD; cd01657; Ribosomal_L7_archeal_euk; 1.
DR Gene3D; 3.30.1390.20; -; 1.
DR InterPro; IPR036919; L30_ferredoxin-like_sf.
DR InterPro; IPR018038; Ribosomal_L30_CS.
DR InterPro; IPR016082; Ribosomal_L30_ferredoxin-like.
DR InterPro; IPR012988; Ribosomal_L30_N.
DR InterPro; IPR039699; Ribosomal_L7/L30.
DR InterPro; IPR005998; Ribosomal_L7_euk.
DR InterPro; IPR035808; Ribosomal_L7_euk_arc.
DR PANTHER; PTHR11524; PTHR11524; 1.
DR Pfam; PF00327; Ribosomal_L30; 1.
DR Pfam; PF08079; Ribosomal_L30_N; 1.
DR SUPFAM; SSF55129; SSF55129; 1.
DR TIGRFAMs; TIGR01310; uL30_euk; 1.
DR PROSITE; PS00634; RIBOSOMAL_L30; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding.
FT CHAIN 1..246
FT /note="60S ribosomal protein L7"
FT /id="PRO_0000104637"
SQ SEQUENCE 246 AA; 27932 MW; 39EB959191E49E02 CRC64;
MSQKVATKTA PVPESILKKR ATSQKKAVDV AKLGRAQQLR NSRLNSVYFK RAEKYVSEYH
KTEREAIRLN RIAKNSGTFY VPPAAKVAFV IRIRGINGVS PKPRKVLKLL RLLQLNNGVF
VKLNKASINM LKLVEPYVAY GFPNLKSIKE LIYKRGHLKI DGQRIPLTSN DMVEKQLGKF
GIICVEDIIH EITTCGKHFK QVNNSLWPFK LNCPRGGFNM KKTPFLQGGD AGNREHLINN
LIHRMN
