RL7_HELPJ
ID RL7_HELPJ Reviewed; 125 AA.
AC P56875;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368}; OrderedLocusNames=jhp_1122;
OS Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J99 / ATCC 700824;
RX PubMed=9923682; DOI=10.1038/16495;
RA Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT "Genomic sequence comparison of two unrelated isolates of the human gastric
RT pathogen Helicobacter pylori.";
RL Nature 397:176-180(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=HP921023;
RX PubMed=10456921; DOI=10.1128/iai.67.9.4713-4719.1999;
RA Hocking D., Webb E., Radcliff F., Rothel L., Taylor S., Pinczower G.,
RA Kapouleas C., Braley H., Lee A., Doidge C.;
RT "Isolation of recombinant protective Helicobacter pylori antigens.";
RL Infect. Immun. 67:4713-4719(1999).
CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC interact with GTP-bound translation factors. Is thus essential for
CC accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC Rule:MF_00368}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR EMBL; AE001439; AAD06700.1; -; Genomic_DNA.
DR EMBL; U86609; AAB47278.1; -; Genomic_DNA.
DR PIR; C71846; C71846.
DR RefSeq; WP_001018228.1; NZ_CP011330.1.
DR AlphaFoldDB; P56875; -.
DR SMR; P56875; -.
DR STRING; 85963.jhp_1122; -.
DR EnsemblBacteria; AAD06700; AAD06700; jhp_1122.
DR GeneID; 66522385; -.
DR KEGG; hpj:jhp_1122; -.
DR PATRIC; fig|85963.30.peg.1455; -.
DR eggNOG; COG0222; Bacteria.
DR OMA; LEDKWGV; -.
DR Proteomes; UP000000804; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00387; Ribosomal_L7_L12; 1.
DR Gene3D; 1.20.5.710; -; 1.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR InterPro; IPR000206; Ribosomal_L7/12.
DR InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR InterPro; IPR013823; Ribosomal_L7/L12_C.
DR InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR PANTHER; PTHR45987; PTHR45987; 1.
DR Pfam; PF00542; Ribosomal_L12; 1.
DR Pfam; PF16320; Ribosomal_L12_N; 1.
DR SUPFAM; SSF48300; SSF48300; 1.
DR SUPFAM; SSF54736; SSF54736; 1.
DR TIGRFAMs; TIGR00855; L12; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..125
FT /note="50S ribosomal protein L7/L12"
FT /id="PRO_0000157537"
SQ SEQUENCE 125 AA; 13314 MW; E2406D8909350C8B CRC64;
MAISKEEVLE YIGSLSVLEL SELVKMFEEK FGVSATPTVV AGAAVAGGAA AESEEKTEFN
VILADSGAEK IKVIKVVREI TGLGLKEAKD ATEKTPHVLK EGVNKEEAET IKKKLEEVGA
KVEVK
