ID   RL7_MACFA               Reviewed;         247 AA.
AC   Q4R506;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=60S ribosomal protein L7;
GN   Name=RPL7; ORFNames=QflA-14483;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Frontal cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. Binds to G-rich structures in 28S rRNA and in
CC       mRNAs. Plays a regulatory role in the translation apparatus; inhibits
CC       cell-free translation of mRNAs. {ECO:0000250|UniProtKB:P18124}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit. Homodimer. Interacts
CC       with DHX33. {ECO:0000250|UniProtKB:P18124}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P18124}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL30 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB169738; BAE01819.1; -; mRNA.
DR   RefSeq; NP_001271527.1; NM_001284598.1.
DR   AlphaFoldDB; Q4R506; -.
DR   SMR; Q4R506; -.
DR   STRING; 9541.XP_005563591.1; -.
DR   PRIDE; Q4R506; -.
DR   GeneID; 101866393; -.
DR   CTD; 6129; -.
DR   eggNOG; KOG3184; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR   CDD; cd01657; Ribosomal_L7_archeal_euk; 1.
DR   Gene3D; 3.30.1390.20; -; 2.
DR   InterPro; IPR036919; L30_ferredoxin-like_sf.
DR   InterPro; IPR018038; Ribosomal_L30_CS.
DR   InterPro; IPR016082; Ribosomal_L30_ferredoxin-like.
DR   InterPro; IPR012988; Ribosomal_L30_N.
DR   InterPro; IPR039699; Ribosomal_L7/L30.
DR   InterPro; IPR005998; Ribosomal_L7_euk.
DR   InterPro; IPR035808; Ribosomal_L7_euk_arc.
DR   PANTHER; PTHR11524; PTHR11524; 1.
DR   Pfam; PF00327; Ribosomal_L30; 1.
DR   Pfam; PF08079; Ribosomal_L30_N; 1.
DR   SUPFAM; SSF55129; SSF55129; 1.
DR   TIGRFAMs; TIGR01310; uL30_euk; 1.
DR   PROSITE; PS00634; RIBOSOMAL_L30; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cytoplasm; Phosphoprotein; Reference proteome; Repeat;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding.
FT   CHAIN           1..247
FT                   /note="60S ribosomal protein L7"
FT                   /id="PRO_0000262919"
FT   REPEAT          7..17
FT                   /note="1"
FT   REPEAT          18..29
FT                   /note="2"
FT   REPEAT          30..41
FT                   /note="3"
FT   REPEAT          42..53
FT                   /note="4"
FT   REGION          7..53
FT                   /note="4 X 12 AA tandem repeats"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:P18124"
FT   MOD_RES         16
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P18124"
FT   MOD_RES         123
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P18124"
FT   MOD_RES         126
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P14148"
FT   MOD_RES         138
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:P18124"
SQ   SEQUENCE   247 AA;  29009 MW;  E50DF5C9852E5D0C CRC64;
     MEGAEEKKKV PAVPETLKKK RRNFAELKIK RLRKKFAQKM LRKARRKLIY EKAKHYHKEY
     RQMYRTEIRM ARMARKAGNF YVPAEPKLAF VIRIRGINGV SPKVRKVLQL LRLRQIFNGT
     FVKLNKASIN MLRIVEPYIA WGYPNLKSVN ELIYKRGYGK INKKRIALTD NALIARSLGK
     YGIICMEDLI HEICTVGKRF KEANNFLWPF KLSSPRGGMK KKTTHFVEGG DAGNREDQIN
     RLIRRMN