ID   RL7_MYCLE               Reviewed;         130 AA.
AC   P30763;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 2.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN   Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368}; OrderedLocusNames=ML1895;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8446028; DOI=10.1111/j.1365-2958.1993.tb01112.x;
RA   Honore N.T., Bergh S., Chanteau S., Doucet-Populaire F., Eiglmeier K.,
RA   Garnier T., Georges C., Launois P., Limpaiboon T., Newton S., Niang K.,
RA   del Portillo P., Ramesh G.R., Reddi P., Ridel P.R., Sittisombut N.,
RA   Wu-Hunter S., Cole S.T.;
RT   "Nucleotide sequence of the first cosmid from the Mycobacterium leprae
RT   genome project: structure and function of the Rif-Str regions.";
RL   Mol. Microbiol. 7:207-214(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC       interact with GTP-bound translation factors. Is thus essential for
CC       accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC   -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC       subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC       elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC       fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC       Rule:MF_00368}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR   EMBL; Z14314; CAA78666.1; -; Genomic_DNA.
DR   EMBL; AL583923; CAC30849.1; -; Genomic_DNA.
DR   PIR; A87146; A87146.
DR   PIR; S31143; S31143.
DR   RefSeq; NP_302275.1; NC_002677.1.
DR   RefSeq; WP_010908596.1; NC_002677.1.
DR   AlphaFoldDB; P30763; -.
DR   SMR; P30763; -.
DR   STRING; 272631.ML1895; -.
DR   EnsemblBacteria; CAC30849; CAC30849; CAC30849.
DR   KEGG; mle:ML1895; -.
DR   PATRIC; fig|272631.5.peg.3592; -.
DR   Leproma; ML1895; -.
DR   eggNOG; COG0222; Bacteria.
DR   HOGENOM; CLU_086499_3_0_11; -.
DR   OMA; LEDKWGV; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00387; Ribosomal_L7_L12; 1.
DR   Gene3D; 1.20.5.710; -; 1.
DR   Gene3D; 3.30.1390.10; -; 1.
DR   HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR   InterPro; IPR000206; Ribosomal_L7/12.
DR   InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR   InterPro; IPR013823; Ribosomal_L7/L12_C.
DR   InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR   InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR   PANTHER; PTHR45987; PTHR45987; 1.
DR   Pfam; PF00542; Ribosomal_L12; 1.
DR   Pfam; PF16320; Ribosomal_L12_N; 1.
DR   SUPFAM; SSF48300; SSF48300; 1.
DR   SUPFAM; SSF54736; SSF54736; 1.
DR   TIGRFAMs; TIGR00855; L12; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..130
FT                   /note="50S ribosomal protein L7/L12"
FT                   /id="PRO_0000157549"
FT   CONFLICT        89..90
FT                   /note="GL -> AV (in Ref. 1; CAA78666)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   130 AA;  13593 MW;  8329AC5ED3FF2130 CRC64;
     MSKLSSDELL DVFKEMTLLE LSDFVKKFEE TFEVTAAAPV SVAVAGAPAA GEAGEAAEEQ
     SEFDVILESA GDKKIGVIKV VREIVSGLGL KEAKDLVDGV PKLLLEKVAK EAADDAKAKL
     EATGATVSVK