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RL7_NEIMH
ID   RL7_NEIMH               Reviewed;         123 AA.
AC   E6MUA0;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-MAR-2011, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN   Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368};
GN   OrderedLocusNames=NMBH4476_0128; ORFNames=NMH_0346;
OS   Neisseria meningitidis serogroup B / serotype 15 (strain H44/76).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=909420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H44/76;
RA   Piet J.R., Huis in 't Veld R., van Schaik B., van Kampen A., Baas F.,
RA   van de Beek D., Pannekoek Y., van der Ende A.;
RT   "Genome Sequence of Neisseria meningitidis serogroup B strain H44/76.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H44/76;
RX   PubMed=21368196; DOI=10.1073/pnas.1019751108;
RA   Budroni S., Siena E., Hotopp J.C., Seib K.L., Serruto D., Nofroni C.,
RA   Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S.V., Covacci A.,
RA   Pizza M., Rappuoli R., Moxon E.R., Tettelin H., Medini D.;
RT   "Neisseria meningitidis is structured in clades associated with restriction
RT   modification systems that modulate homologous recombination.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-21.
RC   STRAIN=H44/76;
RX   PubMed=9025278; DOI=10.1099/00221287-143-1-55;
RA   Kolberg J., Hoiby E.A., Lopez R., Sletten K.;
RT   "Monoclonal antibodies against Streptococcus pneumoniae detect epitopes on
RT   eubacterial ribosomal proteins L7/L12 and on streptococcal elongation
RT   factor Ts.";
RL   Microbiology 143:55-61(1997).
CC   -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC       interact with GTP-bound translation factors. Is thus essential for
CC       accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC   -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC       subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC       elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC       fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC       Rule:MF_00368}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR   EMBL; AEQZ01000003; EFV64912.1; -; Genomic_DNA.
DR   EMBL; CP002420; ADY94799.1; -; Genomic_DNA.
DR   RefSeq; WP_002215374.1; NZ_AEQZ01000003.1.
DR   AlphaFoldDB; E6MUA0; -.
DR   SMR; E6MUA0; -.
DR   EnsemblBacteria; EFV64912; EFV64912; NMH_0346.
DR   GeneID; 61282280; -.
DR   KEGG; nmh:NMBH4476_0128; -.
DR   PATRIC; fig|909420.3.peg.164; -.
DR   HOGENOM; CLU_086499_3_2_4; -.
DR   OMA; LEDKWGV; -.
DR   BioCyc; NMEN909420:NMBH4476_RS00755-MON; -.
DR   Proteomes; UP000032707; Unassembled WGS sequence.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00387; Ribosomal_L7_L12; 1.
DR   Gene3D; 1.20.5.710; -; 1.
DR   Gene3D; 3.30.1390.10; -; 1.
DR   HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR   InterPro; IPR000206; Ribosomal_L7/12.
DR   InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR   InterPro; IPR013823; Ribosomal_L7/L12_C.
DR   InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR   InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR   PANTHER; PTHR45987; PTHR45987; 1.
DR   Pfam; PF00542; Ribosomal_L12; 1.
DR   Pfam; PF16320; Ribosomal_L12_N; 1.
DR   SUPFAM; SSF48300; SSF48300; 1.
DR   SUPFAM; SSF54736; SSF54736; 1.
DR   TIGRFAMs; TIGR00855; L12; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:9025278"
FT   CHAIN           2..123
FT                   /note="50S ribosomal protein L7/L12"
FT                   /id="PRO_0000411120"
SQ   SEQUENCE   123 AA;  12622 MW;  5A6607CA5CB6F535 CRC64;
     MAITKEDILE AVGSLTVMEL NDLVKAFEEK FGVSAAAVAV AGPAGAGAAD AEEKTEFDVV
     LASAGDQKVG VIKVVRAITG LGLKEAKDIV DGAPKTIKEG VSKAEAEDIQ KQLEEAGAKV
     EIK
 
 
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