RL7_STAA8
ID RL7_STAA8 Reviewed; 122 AA.
AC P48860; Q2G0N8;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368};
GN OrderedLocusNames=SAOUHSC_00521;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 50-122.
RX PubMed=7772603; DOI=10.1016/0167-4781(95)00054-k;
RA Aboshkiwa M.A., Rowland G., Coleman G.;
RT "Nucleotide sequence of the Staphylococcus aureus RNA polymerase rpoB gene
RT and comparison of its predicted amino acid sequence with those of other
RT bacteria.";
RL Biochim. Biophys. Acta 1262:73-78(1995).
CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC interact with GTP-bound translation factors. Is thus essential for
CC accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC Rule:MF_00368}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR EMBL; CP000253; ABD29670.1; -; Genomic_DNA.
DR EMBL; X64172; CAA45510.1; -; Genomic_DNA.
DR PIR; S59954; S59954.
DR RefSeq; WP_001273586.1; NZ_LS483365.1.
DR RefSeq; YP_499094.1; NC_007795.1.
DR AlphaFoldDB; P48860; -.
DR SMR; P48860; -.
DR STRING; 1280.SAXN108_0594; -.
DR EnsemblBacteria; ABD29670; ABD29670; SAOUHSC_00521.
DR GeneID; 3920375; -.
DR GeneID; 66838832; -.
DR KEGG; sao:SAOUHSC_00521; -.
DR PATRIC; fig|93061.5.peg.468; -.
DR eggNOG; COG0222; Bacteria.
DR HOGENOM; CLU_086499_3_2_9; -.
DR OMA; LEDKWGV; -.
DR PRO; PR:P48860; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd00387; Ribosomal_L7_L12; 1.
DR Gene3D; 1.20.5.710; -; 1.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR InterPro; IPR000206; Ribosomal_L7/12.
DR InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR InterPro; IPR013823; Ribosomal_L7/L12_C.
DR InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR PANTHER; PTHR45987; PTHR45987; 1.
DR Pfam; PF00542; Ribosomal_L12; 1.
DR Pfam; PF16320; Ribosomal_L12_N; 1.
DR SUPFAM; SSF48300; SSF48300; 1.
DR SUPFAM; SSF54736; SSF54736; 1.
DR TIGRFAMs; TIGR00855; L12; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..122
FT /note="50S ribosomal protein L7/L12"
FT /id="PRO_0000157580"
SQ SEQUENCE 122 AA; 12712 MW; F82ECF574579AF87 CRC64;
MANHEQIIEA IKEMSVLELN DLVKAIEEEF GVTAAAPVAV AGAAGGADAA AEKTEFDVEL
TSAGSSKIKV VKAVKEATGL GLKDAKELVD GAPKVIKEAL PKEEAEKLKE QLEEVGATVE
LK