ID   RL7_STRPN               Reviewed;         122 AA.
AC   P0A471; P80714;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN   Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368}; OrderedLocusNames=SP_1354;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
RN   [2]
RP   PROTEIN SEQUENCE OF 2-43.
RX   PubMed=9025278; DOI=10.1099/00221287-143-1-55;
RA   Kolberg J., Hoiby E.A., Lopez R., Sletten K.;
RT   "Monoclonal antibodies against Streptococcus pneumoniae detect epitopes on
RT   eubacterial ribosomal proteins L7/L12 and on streptococcal elongation
RT   factor Ts.";
RL   Microbiology 143:55-61(1997).
CC   -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC       interact with GTP-bound translation factors. Is thus essential for
CC       accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC   -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC       subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC       elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC       fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC       Rule:MF_00368}.
CC   -!- INTERACTION:
CC       P0A471; Q37995: orf10; Xeno; NbExp=2; IntAct=EBI-11615974, EBI-3990226;
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR   EMBL; AE005672; AAK75452.1; -; Genomic_DNA.
DR   PIR; C95157; C95157.
DR   RefSeq; WP_001196960.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; P0A471; -.
DR   SMR; P0A471; -.
DR   IntAct; P0A471; 1.
DR   STRING; 170187.SP_1354; -.
DR   PRIDE; P0A471; -.
DR   EnsemblBacteria; AAK75452; AAK75452; SP_1354.
DR   GeneID; 60233379; -.
DR   GeneID; 66806471; -.
DR   KEGG; spn:SP_1354; -.
DR   eggNOG; COG0222; Bacteria.
DR   OMA; LEDKWGV; -.
DR   BioCyc; SPNE170187:G1FZB-1360-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00387; Ribosomal_L7_L12; 1.
DR   Gene3D; 1.20.5.710; -; 1.
DR   Gene3D; 3.30.1390.10; -; 1.
DR   HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR   InterPro; IPR000206; Ribosomal_L7/12.
DR   InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR   InterPro; IPR013823; Ribosomal_L7/L12_C.
DR   InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR   InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR   PANTHER; PTHR45987; PTHR45987; 1.
DR   Pfam; PF00542; Ribosomal_L12; 1.
DR   Pfam; PF16320; Ribosomal_L12_N; 1.
DR   SUPFAM; SSF48300; SSF48300; 1.
DR   SUPFAM; SSF54736; SSF54736; 1.
DR   TIGRFAMs; TIGR00855; L12; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:9025278"
FT   CHAIN           2..122
FT                   /note="50S ribosomal protein L7/L12"
FT                   /id="PRO_0000157588"
SQ   SEQUENCE   122 AA;  12442 MW;  E2AF6972B326E09D CRC64;
     MALNIENIIA EIKEASILEL NDLVKAIEEE FGVTAAAPVA VAAADAADAG AAKDSFDVEL
     TSAGDKKVGV IKVVREITGL GLKEAKELVD GAPALVKEGV ATAEAEEIKA KLEEAGASVT
     LK