RL7_SYNY3
ID RL7_SYNY3 Reviewed; 128 AA.
AC P23349;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=50S ribosomal protein L7/L12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN Name=rplL {ECO:0000255|HAMAP-Rule:MF_00368};
GN Synonyms=rpl12 {ECO:0000255|HAMAP-Rule:MF_00368};
GN OrderedLocusNames=sll1746;
OS Synechocystis sp. (strain PCC 6803 / Kazusa).
OC Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC unclassified Synechocystis.
OX NCBI_TaxID=1111708;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2119815; DOI=10.1016/0167-4781(90)90142-o;
RA Sibold C., Subramanian A.R.;
RT "Cloning and characterization of the genes for ribosomal proteins L10 and
RT L12 from Synechocystis Sp. PCC 6803: comparison of gene clustering pattern
RT and protein sequence homology between cyanobacteria and chloroplasts.";
RL Biochim. Biophys. Acta 1050:61-68(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6803 / Kazusa;
RX PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 117-128.
RX PubMed=7505271; DOI=10.1016/s0021-9258(19)74268-9;
RA Schmidt J., Bubunenko M., Subramanian A.R.;
RT "A novel operon organization involving the genes for chorismate synthase
RT (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11,
RT L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803.";
RL J. Biol. Chem. 268:27447-27457(1993).
RN [4]
RP PROTEIN SEQUENCE OF 2-8.
RX PubMed=9298645; DOI=10.1002/elps.1150180806;
RA Sazuka T., Ohara O.;
RT "Towards a proteome project of cyanobacterium Synechocystis sp. strain
RT PCC6803: linking 130 protein spots with their respective genes.";
RL Electrophoresis 18:1252-1258(1997).
CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC interact with GTP-bound translation factors. Is thus essential for
CC accurate translation. {ECO:0000255|HAMAP-Rule:MF_00368}.
CC -!- SUBUNIT: Homodimer. Part of the ribosomal stalk of the 50S ribosomal
CC subunit. Forms a multimeric L10(L12)X complex, where L10 forms an
CC elongated spine to which 2 to 4 L12 dimers bind in a sequential
CC fashion. Binds GTP-bound translation factors. {ECO:0000255|HAMAP-
CC Rule:MF_00368}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL12 family.
CC {ECO:0000255|HAMAP-Rule:MF_00368}.
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DR EMBL; X53178; CAA37318.1; -; Genomic_DNA.
DR EMBL; BA000022; BAA17416.1; -; Genomic_DNA.
DR EMBL; X67516; CAA47854.1; -; Genomic_DNA.
DR PIR; S13069; S13069.
DR AlphaFoldDB; P23349; -.
DR SMR; P23349; -.
DR IntAct; P23349; 1.
DR STRING; 1148.1652495; -.
DR PaxDb; P23349; -.
DR PRIDE; P23349; -.
DR EnsemblBacteria; BAA17416; BAA17416; BAA17416.
DR KEGG; syn:sll1746; -.
DR eggNOG; COG0222; Bacteria.
DR InParanoid; P23349; -.
DR OMA; LEDKWGV; -.
DR PhylomeDB; P23349; -.
DR Proteomes; UP000001425; Chromosome.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd00387; Ribosomal_L7_L12; 1.
DR Gene3D; 1.20.5.710; -; 1.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00368; Ribosomal_L7_L12; 1.
DR InterPro; IPR000206; Ribosomal_L7/12.
DR InterPro; IPR014719; Ribosomal_L7/12_C/ClpS-like.
DR InterPro; IPR013823; Ribosomal_L7/L12_C.
DR InterPro; IPR008932; Ribosomal_L7/L12_oligo.
DR InterPro; IPR036235; Ribosomal_L7/L12_oligo_N_sf.
DR PANTHER; PTHR45987; PTHR45987; 1.
DR Pfam; PF00542; Ribosomal_L12; 1.
DR Pfam; PF16320; Ribosomal_L12_N; 1.
DR SUPFAM; SSF48300; SSF48300; 1.
DR SUPFAM; SSF54736; SSF54736; 1.
DR TIGRFAMs; TIGR00855; L12; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:9298645"
FT CHAIN 2..128
FT /note="50S ribosomal protein L7/L12"
FT /id="PRO_0000157595"
SQ SEQUENCE 128 AA; 13259 MW; FCBF73A205A53946 CRC64;
MSAATDQILE QLKSLSLLEA SELVKQIEEA FGVSAAAPVG GMVMAAAAAA PAEAAEEKTE
FDVILEEVPA DKKIAVLKVV RTITGLGLKE AKELVESTPK AIKEATGKDD AEAIKKQIEE
AGGKAAVK
