RL9_DROME
ID RL9_DROME Reviewed; 190 AA.
AC P50882; A4V0M0; Q4V5D8; Q9VKL6; Q9VKL7;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 2.
DT 03-AUG-2022, entry version 163.
DE RecName: Full=60S ribosomal protein L9;
GN Name=RpL9; Synonyms=M(2)32D; ORFNames=CG6141;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Canton-S; TISSUE=Embryo;
RX PubMed=8676882; DOI=10.1007/bf02172530;
RA Schmidt A., Hollmann M., Schaefer U.;
RT "A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9
RT in Drosophila melanogaster.";
RL Mol. Gen. Genet. 251:381-387(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Embryo;
RA Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Pacleb J.M.,
RA Park S., Wan K.H., Yu C., Celniker S.E.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP STRUCTURE BY ELECTRON MICROSCOPY (6.0 ANGSTROMS) OF THE 80S RIBOSOME.
RX PubMed=23636399; DOI=10.1038/nature12104;
RA Anger A.M., Armache J.P., Berninghausen O., Habeck M., Subklewe M.,
RA Wilson D.N., Beckmann R.;
RT "Structures of the human and Drosophila 80S ribosome.";
RL Nature 497:80-85(2013).
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family.
CC {ECO:0000305}.
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DR EMBL; X94613; CAA64319.1; -; Genomic_DNA.
DR EMBL; AE014134; AAF53048.2; -; Genomic_DNA.
DR EMBL; AE014134; AAF53049.1; -; Genomic_DNA.
DR EMBL; BT022718; AAY55134.1; -; mRNA.
DR PIR; JC6062; JC6062.
DR RefSeq; NP_001285826.1; NM_001298897.1.
DR RefSeq; NP_477161.1; NM_057813.4.
DR RefSeq; NP_723644.1; NM_164955.2.
DR PDB; 4V6W; EM; 6.00 A; CH=1-190.
DR PDB; 6XU6; EM; 3.50 A; CH=1-190.
DR PDB; 6XU7; EM; 4.90 A; CH=1-190.
DR PDB; 6XU8; EM; 3.00 A; CH=1-190.
DR PDBsum; 4V6W; -.
DR PDBsum; 6XU6; -.
DR PDBsum; 6XU7; -.
DR PDBsum; 6XU8; -.
DR AlphaFoldDB; P50882; -.
DR SMR; P50882; -.
DR BioGRID; 60590; 110.
DR DIP; DIP-20042N; -.
DR IntAct; P50882; 14.
DR MINT; P50882; -.
DR STRING; 7227.FBpp0079752; -.
DR PaxDb; P50882; -.
DR PRIDE; P50882; -.
DR DNASU; 34526; -.
DR EnsemblMetazoa; FBtr0080163; FBpp0079752; FBgn0015756.
DR EnsemblMetazoa; FBtr0080164; FBpp0079753; FBgn0015756.
DR EnsemblMetazoa; FBtr0340226; FBpp0309201; FBgn0015756.
DR GeneID; 34526; -.
DR KEGG; dme:Dmel_CG6141; -.
DR CTD; 6133; -.
DR FlyBase; FBgn0015756; RpL9.
DR VEuPathDB; VectorBase:FBgn0015756; -.
DR eggNOG; KOG3255; Eukaryota.
DR HOGENOM; CLU_065464_0_0_1; -.
DR InParanoid; P50882; -.
DR OMA; VFQDGIY; -.
DR OrthoDB; 1408258at2759; -.
DR PhylomeDB; P50882; -.
DR Reactome; R-DME-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-DME-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-DME-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-DME-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-DME-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-DME-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR SignaLink; P50882; -.
DR BioGRID-ORCS; 34526; 1 hit in 1 CRISPR screen.
DR ChiTaRS; RpL9; fly.
DR GenomeRNAi; 34526; -.
DR PRO; PR:P50882; -.
DR Proteomes; UP000000803; Chromosome 2L.
DR Bgee; FBgn0015756; Expressed in eye disc (Drosophila) and 23 other tissues.
DR ExpressionAtlas; P50882; baseline and differential.
DR Genevisible; P50882; DM.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0022626; C:cytosolic ribosome; IDA:FlyBase.
DR GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:FlyBase.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR Gene3D; 3.90.930.12; -; 2.
DR InterPro; IPR000702; Ribosomal_L6.
DR InterPro; IPR020040; Ribosomal_L6_a/b-dom.
DR InterPro; IPR036789; Ribosomal_L6_a/b-dom_sf.
DR InterPro; IPR002359; Ribosomal_L6_CS2.
DR PANTHER; PTHR11655; PTHR11655; 1.
DR Pfam; PF00347; Ribosomal_L6; 2.
DR PIRSF; PIRSF002162; Ribosomal_L6; 1.
DR SUPFAM; SSF56053; SSF56053; 2.
DR PROSITE; PS00700; RIBOSOMAL_L6_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..190
FT /note="60S ribosomal protein L9"
FT /id="PRO_0000131102"
FT CONFLICT 37
FT /note="S -> T (in Ref. 1; CAA64319)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 190 AA; 21392 MW; 689B2520ACDA12D3 CRC64;
MRTINSNQCV KIPKDIKASV KARVVTITGT RGTLKRSFKH LALDMYMPDK RTLKVEKWFG
TKKELAAVRT VCSHIENMIK GVTFGFQYKM RAVYAHFPIN CVTSENNTVI EIRNFLGEKY
IRRVEMAPGV TVVNSTAQKD ELIVEGNDIE SVSGSAALIQ QSTTVKNKDI RKFLDGLYVS
EKTTVVKLES
