AB10G_ARATH
ID AB10G_ARATH Reviewed; 590 AA.
AC Q9MAH4;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=ABC transporter G family member 10;
DE Short=ABC transporter ABCG.10;
DE Short=AtABCG10;
DE AltName: Full=Probable white-brown complex homolog protein 10;
DE Short=AtWBC10;
GN Name=ABCG10; Synonyms=WBC10; OrderedLocusNames=At1g53270;
GN ORFNames=F12M16.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
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DR EMBL; AC008007; AAF69534.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32915.1; -; Genomic_DNA.
DR PIR; B96573; B96573.
DR RefSeq; NP_175734.1; NM_104205.2.
DR AlphaFoldDB; Q9MAH4; -.
DR SMR; Q9MAH4; -.
DR BioGRID; 26986; 28.
DR IntAct; Q9MAH4; 25.
DR STRING; 3702.AT1G53270.1; -.
DR TCDB; 3.A.1.204.42; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q9MAH4; -.
DR PRIDE; Q9MAH4; -.
DR ProteomicsDB; 245117; -.
DR EnsemblPlants; AT1G53270.1; AT1G53270.1; AT1G53270.
DR GeneID; 841761; -.
DR Gramene; AT1G53270.1; AT1G53270.1; AT1G53270.
DR KEGG; ath:AT1G53270; -.
DR Araport; AT1G53270; -.
DR TAIR; locus:2009640; AT1G53270.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_8_1; -.
DR InParanoid; Q9MAH4; -.
DR OMA; NFMLQFP; -.
DR OrthoDB; 1022017at2759; -.
DR PhylomeDB; Q9MAH4; -.
DR PRO; PR:Q9MAH4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9MAH4; baseline and differential.
DR Genevisible; Q9MAH4; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..590
FT /note="ABC transporter G family member 10"
FT /id="PRO_0000240682"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 387..407
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 491..511
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 563..583
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 19..274
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 332..543
FT /note="ABC transmembrane type-2"
FT BINDING 68..75
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 590 AA; 66204 MW; A887A4BEA34041E9 CRC64;
MELPVKAPIP GGREISYRLE TKNLSYRIGG NTPKFSNLCG LLSEKEEKVI LKDVSCDARS
AEITAIAGPS GAGKTTLLEI LAGKVSHGKV SGQVLVNGRP MDGPEYRRVS GFVPQEDALF
PFLTVQETLT YSALLRLKTK RKDAAAKVKR LIQELGLEHV ADSRIGQGSR SGISGGERRR
VSIGVELVHD PNVILIDEPT SGLDSASALQ VVTLLKDMTI KQGKTIVLTI HQPGFRILEQ
IDRIVLLSNG MVVQNGSVYS LHQKIKFSGH QIPRRVNVLE YAIDIAGSLE PIRTQSCREI
SCYGHSKTWK SCYISAGGEL HQSDSHSNSV LEEVQILGQR SCKNIFRTKQ LFTTRALQAS
IAGLILGSIY LNVGNQKKEA KVLRTGFFAF ILTFLLSSTT EGLPIFLQDR RILMRETSRR
AYRVLSYVLA DTLIFIPFLL IISMLFATPV YWLVGLRREL DGFLYFSLVI WIVLLMSNSF
VACFSALVPN FIMGTSVISG LMGSFFLFSG YFIAKDRIPV YWEFMHYLSL FKYPFECLMI
NEYRGDVFLK QQDLKESQKW SNLGIMASFI VGYRVLGFFI LWYRCYRTRS
