AB11A_ARATH
ID AB11A_ARATH Reviewed; 953 AA.
AC Q9FKF2; F4K3L3;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=ABC transporter A family member 11;
DE Short=ABC transporter ABCA.11;
DE Short=AtABCA11;
DE AltName: Full=Putative ABC2 homolog 15;
GN Name=ABCA11; Synonyms=ATH15; OrderedLocusNames=At5g61690;
GN ORFNames=K11J9.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCA family.
CC CPR flippase (TC 3.A.1.211) subfamily. {ECO:0000305}.
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DR EMBL; AB012239; BAB09013.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70574.1; -; Genomic_DNA.
DR RefSeq; NP_001332171.1; NM_001345488.1.
DR AlphaFoldDB; Q9FKF2; -.
DR SMR; Q9FKF2; -.
DR STRING; 3702.AT5G61690.1; -.
DR PaxDb; Q9FKF2; -.
DR PRIDE; Q9FKF2; -.
DR ProteomicsDB; 244557; -.
DR EnsemblPlants; AT5G61690.2; AT5G61690.2; AT5G61690.
DR GeneID; 836291; -.
DR Gramene; AT5G61690.2; AT5G61690.2; AT5G61690.
DR KEGG; ath:AT5G61690; -.
DR Araport; AT5G61690; -.
DR eggNOG; KOG0059; Eukaryota.
DR HOGENOM; CLU_000604_19_5_1; -.
DR InParanoid; Q9FKF2; -.
DR OMA; MRSCSYS; -.
DR OrthoDB; 131191at2759; -.
DR PRO; PR:Q9FKF2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FKF2; baseline and differential.
DR Genevisible; Q9FKF2; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005319; F:lipid transporter activity; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; PTHR19229; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Membrane; Nucleotide-binding; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..953
FT /note="ABC transporter A family member 11"
FT /id="PRO_0000240333"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 277..297
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 519..764
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 565..572
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 953 AA; 104707 MW; 792A7185123083BC CRC64;
MILQEGLPLL YQQFTALFGK NLLLSWRNKR ATCLQIFSSF FFILLIFCIE EAMKASDASS
SAYKNITDPT LLVSPPILPC EDKFFVKLPC YDFVWSGNNS RRVTDIVSAI MANNPGRPIP
TNKVQSFKEP DEVDTWLLSH PLQVPGALHF VERNASVISY GVQTNSSSES KRGQTEDPTF
KFLVPLQVAA EREIARSLLG DPNFGWGLGF KEFARPAIIT ETTSALSVMG PVFFLAFSMF
GFVLQLGALV TEKELKLRQA MTMMGVYDSA YWLSWLTWEG ILTLVSSLFL VLFGMIFRFD
FFLKNSFVLV FLLFLLFQFN MIGLAFALSS IISKSSSATT VGFLVFLIGF ITQFVSATGF
PYSSSYAVSR RVMWSLFPPN TFSAGLKLLL DATSTPKSSG ISWSNRAVCE GGQATCVISI
NIIYQWLLGT FLFWFVLAIY FDNIIPNASG VRKPIFYFLA PGYWTGKGGN KVEEGSIFSC
VGSVPLVEHN TPNDKDVLEE ETEVKQQAMD GIADPNIAVQ IHGLAKTYPG TTKLGCCKCT
KTSPFHAVKG LWMNIAKDQL FCLLGPNGAG KTTTISCLTG INPVTGGDAL IYGDSIRSSV
GISNIRKMIG VCPQFDILWD ALSSEQHLHL FASIKGLPPA SIKSTAEKLL ADVKLTGAAK
VRAGSYSGGM KRRLSVAVAL IGDPKLVFLD EPTTGMDPIT RRHVWDIIQE SKKGRAIILT
THSMEEADIL SDRIGIMAKG RLRCIGTSIR LKSRFGTGFV ATVSFIENKN DNNIGVGASH
EPLKKFFKEH LKVEPTEENK AFMTFVIPHD KENLLTGFFE ELQNRESEFG ISDIQLGLAT
LEEVFLNIAR QAELESATAE GNMVTLELAS GISLEIPVGA RFVGIPDTEN AENPSGVMVE
VYWQQDGSGS MCISGHSSEM RVPQNVPVTR PPSPNALGHK SLRQGVRGIV IDL
