ID   RLA0L_HUMAN             Reviewed;         317 AA.
AC   Q8NHW5;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 134.
DE   RecName: Full=60S acidic ribosomal protein P0-like;
DE   AltName: Full=Large ribosomal subunit protein uL10-like;
GN   Name=RPLP0P6;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Gorry M.C., Zhang Y., Marks J.J., Suppe B., Hart P.S., Corteli J.R.,
RA   Pallos D., Hart T.C.;
RT   "Physical/genetic map of the 2p22-2p21 region on chromosome 2.";
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Cervix carcinoma;
RA   Li W.B., Gruber C., Jessee J., Polayes D.;
RT   "Full-length cDNA libraries and normalization.";
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ribosomal protein P0 is the functional equivalent of E.coli
CC       protein L10. {ECO:0000250}.
CC   -!- SUBUNIT: P0 forms a pentameric complex by interaction with dimers of P1
CC       and P2. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AY064377; AAL62450.1; -; Genomic_DNA.
DR   EMBL; CR596098; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; CH471053; EAX00373.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8NHW5; -.
DR   SMR; Q8NHW5; -.
DR   IntAct; Q8NHW5; 10.
DR   MINT; Q8NHW5; -.
DR   iPTMnet; Q8NHW5; -.
DR   MetOSite; Q8NHW5; -.
DR   PhosphoSitePlus; Q8NHW5; -.
DR   SwissPalm; Q8NHW5; -.
DR   BioMuta; HGNC:36404; -.
DR   DMDM; 74723863; -.
DR   EPD; Q8NHW5; -.
DR   jPOST; Q8NHW5; -.
DR   MassIVE; Q8NHW5; -.
DR   MaxQB; Q8NHW5; -.
DR   PeptideAtlas; Q8NHW5; -.
DR   PRIDE; Q8NHW5; -.
DR   ProteomicsDB; 73779; -.
DR   TopDownProteomics; Q8NHW5; -.
DR   GeneCards; RPLP0P6; -.
DR   HGNC; HGNC:36404; RPLP0P6.
DR   neXtProt; NX_Q8NHW5; -.
DR   InParanoid; Q8NHW5; -.
DR   PathwayCommons; Q8NHW5; -.
DR   SignaLink; Q8NHW5; -.
DR   ChiTaRS; RPLP0P6; human.
DR   Pharos; Q8NHW5; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q8NHW5; protein.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR030670; L10E_eukaryotes.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   PIRSF; PIRSF039087; L10E; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   5: Uncertain;
KW   Isopeptide bond; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Ubl conjugation.
FT   CHAIN           1..317
FT                   /note="60S acidic ribosomal protein P0-like"
FT                   /id="PRO_0000349111"
FT   REGION          292..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..317
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         24
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:P14869"
FT   MOD_RES         59
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P05388"
FT   MOD_RES         304
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05388"
FT   MOD_RES         307
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05388"
FT   CROSSLNK        297
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO1); alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05388"
FT   CROSSLNK        297
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2); alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P05388"
SQ   SEQUENCE   317 AA;  34364 MW;  CEC317735C03FA16 CRC64;
     MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK VVVLMGKNTM
     MRKAIRGHLE NNPALEKLLP HIWGNVGFVF TKEDLTEIRD MLLANKVPAA ARAGAIAPCE
     VTVPAQNTGL GPEKTSFFQA LGITTKISRG TIEILSDVQL IKTGDKVGAS EATLLNMLNI
     SPFSFGLVIQ QVFDNGSIYN PEVLDKTEET LHSRFLEGVR NVASVCLQTG YPTVASVPHS
     IINGYKRVLA LSVETDYTFP LAENVKAFLA DPSAFVAAAP VAADTTAAPA AAAAPAKVEA
     KEESEESDED MGFGLFD