ID   RLA0_DANRE              Reviewed;         319 AA.
AC   Q9PV90;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=60S acidic ribosomal protein P0;
DE   AltName: Full=60S ribosomal protein L10E;
GN   Name=rplp0; Synonyms=arp;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10440850;
RX   DOI=10.1002/(sici)1520-6408(1999)25:2<158::aid-dvg10>3.0.co;2-6;
RA   Ju B., Xu Y., He J., Liao J., Yan T., Hew C.-L., Lam T.J., Gong Z.;
RT   "Faithful expression of green fluorescent protein (GFP) in transgenic
RT   zebrafish embryos under control of zebrafish gene promoters.";
RL   Dev. Genet. 25:158-167(1999).
CC   -!- FUNCTION: Ribosomal protein P0 is the functional equivalent of E.coli
CC       protein L10.
CC   -!- SUBUNIT: P0 forms a pentameric complex by interaction with dimers of P1
CC       and P2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P05388}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P05388}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
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DR   EMBL; AF134852; AAD54776.1; -; mRNA.
DR   AlphaFoldDB; Q9PV90; -.
DR   SMR; Q9PV90; -.
DR   STRING; 7955.ENSDARP00000067953; -.
DR   PaxDb; Q9PV90; -.
DR   ZFIN; ZDB-GENE-000629-1; rplp0.
DR   eggNOG; KOG0815; Eukaryota.
DR   InParanoid; Q9PV90; -.
DR   PhylomeDB; Q9PV90; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q9PV90; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0043009; P:chordate embryonic development; IMP:ZFIN.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR030670; L10E_eukaryotes.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   PIRSF; PIRSF039087; L10E; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..319
FT                   /note="60S acidic ribosomal protein P0"
FT                   /id="PRO_0000154763"
FT   REGION          289..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..319
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   319 AA;  34753 MW;  CE9F47819AD54ABF CRC64;
     MPREDRATWK SNYFLKIIQL LDDFPKCFIV GADNVGSKQM QTIRLSLRGK AVVLMGKNTM
     MRKAIRGHLE NNPALERLLP HIRGNVGFVF TKEDLTEVRD LLLANKVPAA ARAGAIAPCE
     VTVPAQNTGL GPEKTSFFQA LGITTKISRG TIEILSDVQL IKPGDKVGAS EATLLNMLNM
     LNISPFSYGL IIQQVYDNGS VYSPEVLDIT EDALHKRFLK GVRNIASVCL QIGYPTLASI
     PHTIINGYKR VLAVTVETDY TFPLAEKVKA YLADPTAFAV AAPVAAATEQ KSAAPAAKEE
     APKEDSEESD EDMGFGLFD