ID   RLA0_TRYCR              Reviewed;         323 AA.
AC   P26796;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 2.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=60S acidic ribosomal protein P0;
OS   Trypanosoma cruzi.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=5693;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Tulahuen / MHOM/CH/00;
RX   PubMed=1377223; DOI=10.1084/jem.176.1.201;
RA   Skeiky Y.A., Benson D.R., Parsons M., Elkon K.B., Reed S.G.;
RT   "Cloning and expression of Trypanosoma cruzi ribosomal protein P0 and
RT   epitope analysis of anti-P0 autoantibodies in Chagas' disease patients.";
RL   J. Exp. Med. 176:201-211(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=RA;
RX   PubMed=1614881; DOI=10.1093/nar/20.11.2894;
RA   Schijman A.G., Levin M.J.;
RT   "Nucleotide sequence of a cDNA encoding a Trypanosoma cruzi acidic
RT   ribosomal PO protein: a novel C-terminal domain in T. cruzi ribosomal P
RT   proteins.";
RL   Nucleic Acids Res. 20:2894-2894(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 246-323.
RC   STRAIN=Tulahuen 2;
RX   PubMed=1385317; DOI=10.1016/0165-2478(92)90087-5;
RA   Schijman A.G., Levitus G., Levin M.J.;
RT   "Characterization of the C-terminal region of a Trypanosoma cruzi 38-kDa
RT   ribosomal P0 protein that does not react with lupus anti-P
RT   autoantibodies.";
RL   Immunol. Lett. 33:15-20(1992).
CC   -!- FUNCTION: Ribosomal protein P0 is the functional equivalent of E.coli
CC       protein L10.
CC   -!- SUBUNIT: P0 forms a pentameric complex by interaction with dimers of P1
CC       and P2.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
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DR   EMBL; L15558; AAA30236.1; -; mRNA.
DR   EMBL; X65066; CAA46199.1; -; mRNA.
DR   EMBL; X62144; CAA44070.1; -; mRNA.
DR   PIR; JH0752; JH0752.
DR   PIR; S22951; R5UTP0.
DR   AlphaFoldDB; P26796; -.
DR   SMR; P26796; -.
DR   VEuPathDB; TriTrypDB:BCY84_14655; -.
DR   VEuPathDB; TriTrypDB:C3747_9g366; -.
DR   VEuPathDB; TriTrypDB:C4B63_2g518; -.
DR   VEuPathDB; TriTrypDB:Tc_MARK_4185; -.
DR   VEuPathDB; TriTrypDB:TcBrA4_0058080; -.
DR   VEuPathDB; TriTrypDB:TcCL_Unassigned05752; -.
DR   VEuPathDB; TriTrypDB:TcCLB.508355.250; -.
DR   VEuPathDB; TriTrypDB:TCDM_04519; -.
DR   VEuPathDB; TriTrypDB:TcG_06175; -.
DR   VEuPathDB; TriTrypDB:TCSYLVIO_005515; -.
DR   VEuPathDB; TriTrypDB:TcYC6_0073360; -.
DR   OMA; NIGTRIN; -.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR030670; L10E_eukaryotes.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   PIRSF; PIRSF039087; L10E; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..323
FT                   /note="60S acidic ribosomal protein P0"
FT                   /id="PRO_0000154774"
FT   REGION          298..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..323
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        123..124
FT                   /note="IA -> S (in Ref. 2; CAA46199)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        170
FT                   /note="V -> A (in Ref. 2; CAA46199)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        230..232
FT                   /note="AAL -> VV (in Ref. 2; CAA46199)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        287
FT                   /note="V -> A (in Ref. 2; CAA46199)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        293
FT                   /note="A -> V (in Ref. 3; CAA44070)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        294
FT                   /note="A -> T (in Ref. 2; CAA46199)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        308
FT                   /note="P -> F (in Ref. 3; CAA44070)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   323 AA;  34958 MW;  4670BAACA7FFC675 CRC64;
     MPSVSEAKRE YEERFNGCLT KYGRVLFCLM DNVRSQQVHD VRRDLRGLGE LVMGKKTLQK
     KIVERRAEDK KASAYDKLLY NTCIEKKLLC GNTALIFTNE EIPVITAVLD KHRVQAPARV
     GAIAPCDVIV PAGNTGMEPK ATSFFQALNI ATKIAKGTVE IVSDKKVLSV GDRVDNSTAT
     LLQKLDISPF YYQVEVQSVW DRGMLFLRED LSITDDVVEK YLLEGISNVA ALSLGAGIPT
     AATLPHMIMD AFKTLLGASV ATEYEFDEFD GKNLRKAALE GNLGGGVADA AAAADTGAAA
     APAAAAEPEE EDDDDDFGMG ALF