ID   RLA1_CAEEL              Reviewed;         111 AA.
AC   P91913; Q9GR59;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=60S acidic ribosomal protein P1;
DE   AltName: Full=Ribosomal protein large subunit P1;
GN   Name=rla-1; Synonyms=rpa-1; ORFNames=Y37E3.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Bristol N2;
RA   Blaxter M.L., Brodie J.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Plays an important role in the elongation step of protein
CC       synthesis.
CC   -!- SUBUNIT: P1 and P2 exist as dimers at the large ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U89307; AAB48625.1; -; mRNA.
DR   EMBL; FO081769; CCD73427.1; -; Genomic_DNA.
DR   RefSeq; NP_740801.1; NM_170818.4.
DR   AlphaFoldDB; P91913; -.
DR   SMR; P91913; -.
DR   BioGRID; 37253; 101.
DR   IntAct; P91913; 3.
DR   STRING; 6239.Y37E3.7.2; -.
DR   EPD; P91913; -.
DR   PaxDb; P91913; -.
DR   PeptideAtlas; P91913; -.
DR   EnsemblMetazoa; Y37E3.7.1; Y37E3.7.1; WBGene00004409.
DR   EnsemblMetazoa; Y37E3.7.2; Y37E3.7.2; WBGene00004409.
DR   UCSC; F18A1.5; c. elegans.
DR   WormBase; Y37E3.7; CE26658; WBGene00004409; rla-1.
DR   eggNOG; KOG1762; Eukaryota.
DR   GeneTree; ENSGT00940000170577; -.
DR   HOGENOM; CLU_114656_1_0_1; -.
DR   InParanoid; P91913; -.
DR   OMA; EYIYAAM; -.
DR   OrthoDB; 1633925at2759; -.
DR   PhylomeDB; P91913; -.
DR   Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P91913; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00004409; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0030295; F:protein kinase activator activity; IBA:GO_Central.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR   InterPro; IPR001859; T.cruzi_P2-like.
DR   PRINTS; PR00456; RIBOSOMALP2.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..111
FT                   /note="60S acidic ribosomal protein P1"
FT                   /id="PRO_0000157690"
FT   REGION          65..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..105
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        42
FT                   /note="Y -> N (in Ref. 1; AAB48625)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   111 AA;  11284 MW;  6DB5B65BACFCC4A6 CRC64;
     MASNQELACV YAALILQDDE VAITGEKIAT LLKAANVEFE PYWPGLFAKA LEGVDVKNLI
     TSVSSGAGSG PAPAAAAAAP AAGGAAPAAE TKKKEEPKEE SDDDMGFGLF D