ID   RLA1_PENCR              Reviewed;         107 AA.
AC   H2E5X2;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=60S acidic ribosomal protein P1 {ECO:0000303|PubMed:23902156};
DE   AltName: Allergen=Pen cr 26.0101 {ECO:0000305};
OS   Penicillium crustosum (Blue mold fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=36656 {ECO:0000312|EMBL:AEX34122.1};
RN   [1] {ECO:0000312|EMBL:AEX34122.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC   STRAIN=DAOM 231275 {ECO:0000303|PubMed:23902156,
RC   ECO:0000312|EMBL:AEX34122.1};
RX   PubMed=23902156; DOI=10.3109/13693786.2013.813086;
RA   Sevinc M.S., Kumar V., Abebe M., Lemieux M., Vijay H.M.;
RT   "Isolation, expression and characterization of a minor allergen from
RT   Penicillium crustosum.";
RL   Med. Mycol. 52:81-89(2013).
CC   -!- FUNCTION: Plays an important role in the elongation step of protein
CC       synthesis. {ECO:0000305}.
CC   -!- SUBUNIT: P1 and P2 exist as dimers at the large ribosomal subunit.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P05318}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE in 23% of
CC       the 61 patients tested allergic to Penicillium mold.
CC       {ECO:0000269|PubMed:23902156}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000305}.
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DR   EMBL; JN791438; AEX34122.1; -; mRNA.
DR   AlphaFoldDB; H2E5X2; -.
DR   SMR; H2E5X2; -.
DR   Allergome; 10033; Pen cr 26.
DR   Allergome; 10034; Pen cr 26.0101.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0002181; P:cytoplasmic translation; ISS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
PE   1: Evidence at protein level;
KW   Allergen; Cytoplasm; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..107
FT                   /note="60S acidic ribosomal protein P1"
FT                   /id="PRO_0000447995"
FT   REGION          67..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..107
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   107 AA;  11043 MW;  96C86E3199BCF701 CRC64;
     MSTAELACSY AALILADDGI EISADKIQTL ISAANVQEVE PIWASIFARA LEGKDIKELL
     TNVGSAGPAS AAPAGAAGAA APAEEKAEEK EEEKEESDED MGFGLFD