RLA2_CAEEL
ID RLA2_CAEEL Reviewed; 107 AA.
AC O01504;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=60S acidic ribosomal protein P2;
GN ORFNames=C37A2.7 {ECO:0000312|WormBase:C37A2.7};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Plays an important role in the elongation step of protein
CC synthesis.
CC -!- SUBUNIT: P1 and P2 exist as dimers at the large ribosomal subunit.
CC {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC {ECO:0000305}.
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DR EMBL; FO080805; CCD66926.1; -; Genomic_DNA.
DR PIR; T30159; T30159.
DR RefSeq; NP_491944.2; NM_059543.5.
DR AlphaFoldDB; O01504; -.
DR SMR; O01504; -.
DR BioGRID; 37849; 90.
DR DIP; DIP-24496N; -.
DR IntAct; O01504; 1.
DR STRING; 6239.C37A2.7; -.
DR EPD; O01504; -.
DR PaxDb; O01504; -.
DR PeptideAtlas; O01504; -.
DR EnsemblMetazoa; C37A2.7.1; C37A2.7.1; WBGene00016493.
DR GeneID; 172401; -.
DR KEGG; cel:CELE_C37A2.7; -.
DR UCSC; M04F3.1.1; c. elegans.
DR CTD; 172401; -.
DR WormBase; C37A2.7; CE30433; WBGene00016493; -.
DR eggNOG; KOG3449; Eukaryota.
DR GeneTree; ENSGT00550000074828; -.
DR HOGENOM; CLU_114656_0_2_1; -.
DR InParanoid; O01504; -.
DR OMA; NIEDVIC; -.
DR OrthoDB; 1626327at2759; -.
DR PhylomeDB; O01504; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:O01504; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00016493; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0002182; P:cytoplasmic translational elongation; IEA:InterPro.
DR CDD; cd05833; Ribosomal_P2; 1.
DR Gene3D; 1.10.10.1410; -; 1.
DR HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR InterPro; IPR038716; P1/P2_N_sf.
DR InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR InterPro; IPR044076; Ribosomal_P2.
DR PANTHER; PTHR21141; PTHR21141; 1.
PE 3: Inferred from homology;
KW Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..107
FT /note="60S acidic ribosomal protein P2"
FT /id="PRO_0000157649"
FT REGION 63..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 107 AA; 10813 MW; 6BC6C991EADC94E5 CRC64;
MKYLGAYLLA TLGGNASPSA QDVLKVLEAG GLDCDMENAN SVVDALKGKT ISEVIAQGKV
KLSSVPSGGS APAAAAPSGG AAPKAEEKKK EEPKEESDDD MGFGLFD
