RLA2_DAVTA
ID RLA2_DAVTA Reviewed; 111 AA.
AC P42039; P42038;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2002, sequence version 3.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=60S acidic ribosomal protein P2;
DE AltName: Full=Allergen Cla h 3;
DE AltName: Full=Allergen Cla h 4;
DE AltName: Full=Allergen Cla h III;
DE AltName: Full=Allergen Cla h IV;
DE AltName: Full=Minor allergen Cla h 5;
DE AltName: Allergen=Cla h 5;
GN Name=CLAH5; Synonyms=CLAH3, CLAH4;
OS Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Cladosporiales; Cladosporiaceae; Cladosporium.
OX NCBI_TaxID=29918;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC STRAIN=IMI 96220;
RX PubMed=7814877;
RA Zhang L., Muradia G., Curran I.H., Rode H., Vijay H.M.;
RT "A cDNA clone coding for a novel allergen, Cla h III, of Cladosporium
RT herbarum identified as a ribosomal P2 protein.";
RL J. Immunol. 154:710-717(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC STRAIN=280202-Berlin;
RX PubMed=7898496; DOI=10.1016/0161-5890(94)00108-d;
RA Achatz G., Oberkofler H., Lechenauer E., Simon-Nobbe B., Unger A.,
RA Kandler D., Ebner C., Prillinger H., Kraft D., Breitenbach M.;
RT "Molecular cloning of major and minor allergens of Alternaria alternata and
RT Cladosporium herbarum.";
RL Mol. Immunol. 32:213-227(1995).
RN [3]
RP SEQUENCE REVISION TO 13; 38-41 AND 93.
RA Simon-Nobbe B.;
RL Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=17709917; DOI=10.1159/000107578;
RA Simon-Nobbe B., Denk U., Poell V., Rid R., Breitenbach M.;
RT "The spectrum of fungal allergy.";
RL Int. Arch. Allergy Immunol. 145:58-86(2008).
CC -!- FUNCTION: Plays an important role in the elongation step of protein
CC synthesis.
CC -!- SUBUNIT: P1 and P2 exist as dimers at the large ribosomal subunit.
CC -!- ALLERGEN: Causes an allergic reaction in human.
CC {ECO:0000269|PubMed:7814877, ECO:0000269|PubMed:7898496}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC {ECO:0000305}.
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DR EMBL; X77253; CAA54470.1; -; mRNA.
DR EMBL; X78223; CAA55067.2; -; mRNA.
DR PIR; S41866; S41866.
DR PIR; S43115; S43115.
DR AlphaFoldDB; P42039; -.
DR SMR; P42039; -.
DR Allergome; 219; Cla h 5.
DR Allergome; 3204; Cla h 5.0101.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0002182; P:cytoplasmic translational elongation; IEA:InterPro.
DR CDD; cd05833; Ribosomal_P2; 1.
DR Gene3D; 1.10.10.1410; -; 1.
DR HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR InterPro; IPR038716; P1/P2_N_sf.
DR InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR InterPro; IPR044076; Ribosomal_P2.
DR PANTHER; PTHR21141; PTHR21141; 1.
PE 1: Evidence at protein level;
KW Allergen; Phosphoprotein; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..111
FT /note="60S acidic ribosomal protein P2"
FT /id="PRO_0000157677"
FT REGION 61..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..111
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 101
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT CONFLICT 4
FT /note="L -> M (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 7
FT /note="F -> Y (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 60
FT /note="E -> Q (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 70
FT /note="A -> S (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 73
FT /note="A -> AP (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 85
FT /note="A -> T (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
FT CONFLICT 92..94
FT /note="ERA -> AK (in Ref. 1; CAA54470)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 111 AA; 11105 MW; C7B65C6AD997B76A CRC64;
MKYLAAFLLL GLAGNSSPSA EDIKTVLSSV GIDADEERLS SLLKELEGKD INELISSGSE
KLASVPSGGA GAASAGGAAA AGGAAEAAPE AERAEEEKEE SDDDMGFGLF D
