ID   RLA2_DICDI              Reviewed;         106 AA.
AC   P22683; Q54R39;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=60S acidic ribosomal protein P2;
GN   Name=rplp2; ORFNames=DDB_G0283393;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=AX3;
RX   PubMed=1840653; DOI=10.1093/nar/19.6.1341;
RA   Prieto J., Candel E., Coloma A.;
RT   "Nucleotide sequence of a cDNA encoding acidic ribosomal phosphoprotein P2
RT   in Dictyostelium discoideum.";
RL   Nucleic Acids Res. 19:1341-1341(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Plays an important role in the elongation step of protein
CC       synthesis.
CC   -!- SUBUNIT: P1 and P2 exist as dimers at the large ribosomal subunit.
CC   -!- PTM: Phosphorylated.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000305}.
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DR   EMBL; X56192; CAA39655.1; -; mRNA.
DR   EMBL; AAFI02000055; EAL65681.1; -; Genomic_DNA.
DR   PIR; S14014; R6DOP2.
DR   RefSeq; XP_639052.1; XM_633960.1.
DR   AlphaFoldDB; P22683; -.
DR   SMR; P22683; -.
DR   STRING; 44689.DDB0191484; -.
DR   PaxDb; P22683; -.
DR   EnsemblProtists; EAL65681; EAL65681; DDB_G0283393.
DR   GeneID; 8624077; -.
DR   KEGG; ddi:DDB_G0283393; -.
DR   dictyBase; DDB_G0283393; rplP2.
DR   eggNOG; KOG3449; Eukaryota.
DR   HOGENOM; CLU_114656_0_2_1; -.
DR   InParanoid; P22683; -.
DR   OMA; AYLMNVL; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:P22683; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:InterPro.
DR   GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0002182; P:cytoplasmic translational elongation; IEA:InterPro.
DR   CDD; cd05833; Ribosomal_P2; 1.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR   InterPro; IPR044076; Ribosomal_P2.
DR   PANTHER; PTHR21141; PTHR21141; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Phosphoprotein; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..106
FT                   /note="60S acidic ribosomal protein P2"
FT                   /id="PRO_0000157651"
FT   REGION          80..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        86..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  10509 MW;  B3F53E95B6994BD5 CRC64;
     MKYLAAYLLA SLSGNANAAS VTKILQSVGV EVDAARVESV CKELDGKDVQ ALIAAGKSKV
     GSVAAAAAPA AATSAAPAAA AAAPAKKVVE EKKEESDDDM GMGLFD